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Volumn 2, Issue 12, 2007, Pages 779-782

Fragment-based ligand discovery meets phage display

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DERIVATIVE; ADENOSINE TRIPHOSPHATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLOPEPTIDE; DASATINIB; DNA; ERLOTINIB; IMATINIB; LIGAND; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN FOS; PROTEIN KINASE; SMALL INTERFERING RNA; SORAFENIB; STAUROSPORINE; SUNITINIB;

EID: 38649107845     PISSN: 15548929     EISSN: None     Source Type: Journal    
DOI: 10.1021/cb700240b     Document Type: Article
Times cited : (8)

References (17)
  • 1
    • 33644846857 scopus 로고    scopus 로고
    • Small molecules: The missing link in the central dogma
    • Schreiber, S. L. (2005) Small molecules: the missing link in the central dogma, Nat. Chem. Biol. 1, 64-66.
    • (2005) Nat. Chem. Biol , vol.1 , pp. 64-66
    • Schreiber, S.L.1
  • 2
    • 36148932151 scopus 로고    scopus 로고
    • Tethering small molecules to a phage display library: Discovery of a selective bivalent inhibitor of protein kinase A
    • Meyer, S. C., Shomin, C. D., Gaj, T., and Ghosh, I. (2007) Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A, J. Am. Chem. Soc. 129, 13812-13813.
    • (2007) J. Am. Chem. Soc , vol.129 , pp. 13812-13813
    • Meyer, S.C.1    Shomin, C.D.2    Gaj, T.3    Ghosh, I.4
  • 3
    • 33847381100 scopus 로고    scopus 로고
    • A decade of fragment-based drug design: Strategic advances and lessons learned
    • Hajduk, P. J., and Greer, J. (2007) A decade of fragment-based drug design: strategic advances and lessons learned, Nat. Rev. Drug Discovery 6, 211-219.
    • (2007) Nat. Rev. Drug Discovery , vol.6 , pp. 211-219
    • Hajduk, P.J.1    Greer, J.2
  • 6
    • 2942560767 scopus 로고    scopus 로고
    • Phage display-derived peptides as therapeutic alternatives to antibodies
    • Ladner, R. C., Sato, A. K., Gorzelany, J., and de Souza, M. (2004) Phage display-derived peptides as therapeutic alternatives to antibodies, Drug Discovery Today 9, 525-529.
    • (2004) Drug Discovery Today , vol.9 , pp. 525-529
    • Ladner, R.C.1    Sato, A.K.2    Gorzelany, J.3    de Souza, M.4
  • 7
    • 0026063670 scopus 로고
    • Design of potent protein kinase inhibitors using the bisubstrate approach
    • Ricouart, A., Gesquiere, J. C., Tartar, A., and Sergheraert, C. (1991) Design of potent protein kinase inhibitors using the bisubstrate approach, J. Med. Chem. 34, 73-78.
    • (1991) J. Med. Chem , vol.34 , pp. 73-78
    • Ricouart, A.1    Gesquiere, J.C.2    Tartar, A.3    Sergheraert, C.4
  • 9
    • 18844441430 scopus 로고    scopus 로고
    • Increasing the kinase specificity of k252a by protein surface recognition
    • Schneider, T. L., Mathew, R. S., Rice, K. P., Tamaki, K., Wood, J. L., and Schepartz, A. (2005) Increasing the kinase specificity of k252a by protein surface recognition, Org. Lett. 7, 1695-1698.
    • (2005) Org. Lett , vol.7 , pp. 1695-1698
    • Schneider, T.L.1    Mathew, R.S.2    Rice, K.P.3    Tamaki, K.4    Wood, J.L.5    Schepartz, A.6
  • 13
    • 0031024171 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski, C. A., Lombardo, F., Dominy, B. W., and Feeney, P. J. (1997) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings, Adv. Drug Delivery Rev. 23, 3-25.
    • (1997) Adv. Drug Delivery Rev , vol.23 , pp. 3-25
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 14
    • 0000598486 scopus 로고    scopus 로고
    • Using a convenient, quantitative model for torsional entropy to establish qualitative trends for molecular processes that restrict conformational freedom
    • Mammen, M., Shakhnovich, E. I., and Whitesides, G. M. (1998) Using a convenient, quantitative model for torsional entropy to establish qualitative trends for molecular processes that restrict conformational freedom, J. Org. Chem. 63, 3168-3175.
    • (1998) J. Org. Chem , vol.63 , pp. 3168-3175
    • Mammen, M.1    Shakhnovich, E.I.2    Whitesides, G.M.3
  • 15
    • 0028894384 scopus 로고
    • Crystal structure of the heterodimeric bZIP transcription factor c-Fos- c-Jun bound to DNA
    • Glover, J. N., and Harrison, S. C., (1995) Crystal structure of the heterodimeric bZIP transcription factor c-Fos- c-Jun bound to DNA, Nature 373, 257-261.
    • (1995) Nature , vol.373 , pp. 257-261
    • Glover, J.N.1    Harrison, S.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.