Wip1 protects hydrogen peroxide-induced colonic epithelial barrier dysfunction

Cellular and Molecular Life Sciences

Volumn 64, Issue 23, 2007, Pages 3139-3147

  Oshima, T ^a,b   Sasaki, M ^a   Kataoka, H ^a   Miwa, H ^b   Takeuchi, T ^c   Joh, T ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

^c GUNMA UNIVERSITY   (Japan)

Author keywords

Claudin 4; p38 MAP kinase; Permeability; Tight junction; Wip1

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CLAUDIN 4; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PROTEIN; REACTIVE OXYGEN METABOLITE; TRITON X 114; UNCLASSIFIED DRUG; WIP1 PROTEIN;

ARTICLE; ATTENUATION; CELL MEMBRANE PERMEABILITY; COLON MUCOSA; ENTERITIS; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; TIGHT JUNCTION; VIRUS INFECTION;

ADENOVIRIDAE;

EID: 38549181147     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-007-7268-7     Document Type: Article

References (49)

1. Jankowski, J. A., Bedford, F. K., Boulton, R. A., Cruickshank, N., Hall, C., Elder, J., Allan, R., Forbes, A., Kim, Y. S., Wright, N. A. et al. (1998) Alterations in classical cadherins associated with progression in ulcerative and Crohn's colitis. Lab. Invest. 78, 1155-1167.
2. Schmitz, H., Barmeyer, C., Fromm, M., Runkel, N., Foss, H. D., Bentzel, C. J., Riecken, E. O. and Schulzke, J. D. (1999) Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis. Gastroenterology 116, 301-309.
3. Kinugasa, T., Sakaguchi, T., Gu, X. and Reinecker, H. C. (2000) Claudins regulate the intestinal barrier in response to immune mediators. Gastroenterology 118, 1001-1011.
4. North, A. J., Bardsley, W. G., Hyam, J., Bornslaeger, E. A., Cordingley, H. C., Trinnaman, B., Hatzfeld, M., Green, K. J., Magee, A. I. and Garrod, D. R. (1999) Molecular map of the desmosomal plaque. J. Cell Sci. 112 (Pt 23), 4325-4336.
5. Farquhar, M. G. and Palade, G. E. (1963) Junctional complexes in various epithelia. J. Cell Biol. 17, 375-412.
6. Tsukita, S. and Furuse, M. (2000) Pores in the wall: claudins constitute tight junction strands containing aqueous pores. J. Cell Biol. 149, 13-16.
7. Hermiston, M. L. and Gordon, J. I. (1995) Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science 270, 1203-1207.
8. Gumbiner, B. M. (1993) Breaking through the tight junction barrier. J. Cell Biol. 123, 1631-1633.
9. Tsukita, S. , Furuse, M. and Itoh, M. (2001) Multifunctional strands in tight junctions. Nat. Rev. Mol. Cell Biol. 2, 285-293.
10. Hewitt, K. J., Agarwal, R. and Morin, P. J. (2006) The claudin gene family: expression in normal and neoplastic tissues. BMC Cancer 6, 186.
11. Morin, P. J. (2005) Claudin proteins in human cancer: promising new targets for diagnosis and therapy. Cancer Res. 65, 9603-9606.
12. Parks, D. A. (1989) Oxygen radicals: mediators of gastrointestinal pathophysiology. Gut 30, 293-298.
13. Thannickal, V. J. and Fanburg, B. L. (2000) Reactive oxygen species in cell signaling. Am. J. Physiol. Lung Cell. Mol. Physiol. 279, L1005-L1028.
14. Rao, R. K., Baker, R. D., Baker, S. S., Gupta, A. and Holycross, M. (1997) Oxidant-induced disruption of intestinal epithelial barrier function: role of protein tyrosine phosphorylation. Am. J. Physiol. 273, G812-G823.
15. Grisham, M. B., Gaginella, T. S., von Ritter, C., Tamai, H., Be, R. M. and Granger, D. N. (1990) Effects of neutrophil-derived oxidants on intestinal permeability, electrolyte transport, and epithelial cell viability. Inflammation 14, 531-542.
16. Meyer, T. N., Schwesinger, C., Ye, J., Denker, B. M. and Nigam, S. K. (2001) Reassembly of the tight junction after oxidative stress depends on tyrosine kinase activity. J. Biol. Chem. 276, 22048-22055.
17. Hommes, D., van den Blink, B., Plasse, T., Bartelsman, J., Xu, C., Macpherson, B., Tytgat, G., Peppelenbosch, M. and Van Deventer, S. (2002) Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease. Gastroenterology 122, 7-14.
18. Travis, S., Yap, L. M., Hawkey, C., Warren, B., Lazarov, M., Fong, T. and Tesi, R. J. (2005) RDP58 is a novel and potentially effective oral therapy for ulcerative colitis. Inflamm. Bowel Dis. 11, 713-719.
19. Hagemann, C. and Blank, J. L. (2001) The ups and downs of MEK kinase interactions. Cell Signal. 13, 863-875.
20. Bogoyevitch, M. A. and Court, N. W. (2004) Counting on mitogen-activated protein kinases - ERKs 3, 4, 5, 6, 7 and 8. Cell. Signal. 16, 1345-1354.
21. Schneeberger, E. E. and Lynch, R. D. (2004) The tight junction: a multifunctional complex. Am. J. Physiol Cell Physiol 286, C1213-C1228.
22. Matter, K. and Balda, M. S. (2003) Signalling to and from tight junctions. Nat. Rev. Mol .Cell Biol. 4, 225-236.
23. Chen, Y., Lu, Q., Schneeberger, E. E. and Goodenough, D. A. (2000) Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells. Mol. Biol. Cell 11, 849-862.
24. Kevil, C. G., Oshima, T. and Alexander, J. S. (2001) The role of p38 MAP kinase in hydrogen peroxide mediated endothelial solute permeability. Endothelium 8, 107-116.
25. Takekawa, M., Adachi, M., Nakahata, A., Nakayama, I., Itoh, F., Tsukuda, H., Taya, Y. and Imai, K. (2000) p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation. EMBO J. 19, 6517-6526.
26. Fiscella, M., Zhang, H., Fan, S., Sakaguchi, K., Shen, S., Mercer, W. E., Vande Woude, G. F., O'Connor, P. M. and Appella, E. (1997) Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner. Proc. Natl. Acad. Sci. USA 94, 6048-6053.
27. Oshima, T., Laroux, F. S., Coe, L. L., Morise, Z., Kawachi, S., Bauer, P., Grisham, M. B., Specian, R. D., Carter, P., Jennings, S. et al. (2001) Interferon-gamma and interleukin-10 reciprocally regulate endothelial junction integrity and barrier function. Microvasc. Res. 61, 130-143.
28. Oshima, T., Pavlick, K. P., Laroux, F. S., Verma, S. K., Jordan, P., Grisham, M. B., Williams, L. and Alexander, J. S. (2001) Regulation and distribution of MAdCAM-1 in endothelial cells in vitro. Am. J. Physiol. Cell Physiol. 281, C1096-1105.
29. Heid, C. A., Stevens, J., Livak, K. J. and Williams, P. M. (1996) Real time quantitative PCR. Genome Res. 6, 986-994.
30. Gibson, U. E., Heid, C. A. and Williams, P. M. (1996) A novel method for real time quantitative RT-PCR. Genome Res. 6, 995-1001.
31. Nishimura, M., Imai, T., Morioka, Y., Kuribayashi, S., Kamataki, T. and Naito, S. (2004) Effects of NO-1886 (Ibrolipim), a lipoprotein lipase-promoting agent, on gene induction of cytochrome P450 s, carboxylesterases, and sulfotransferases in primary cultures of human hepatocytes. Drug Metab. Pharmacokinet. 19, 422-429.
32. Nishimura, M., Naito, S. and Yokoi, T. (2004) Tissue-specific mRNA expression profiles of human nuclear receptor subfamilies. Drug Metab. Pharmacokinet. 19, 135-149.
33. Maruo, N., Morita, I., Shirao, M. and Murota, S. (1992) IL-6 increases endothelial permeability in vitro. Endocrinology 131, 710-714.
34. Oshima, T., Flores, S. C., Vaitaitis, G., Coe, L. L., Joh, T., Park, J. H., Zhu, Y., Alexander, B. and Alexander, J. S. (2000) HIV-1 Tat increases endothelial solute permeability through tyrosine kinase and mitogen-activated protein kinase-dependent pathways. AIDS 14, 475-482.
35. Oshima, T., Blaschuk, O., Gour, B., Symonds, M., Elrod, J. W., Sasaki, M., Jackson, T. H. and Alexander, J. S. (2003) Tight junction peptide antagonists enhance neutrophil trans-endothelial chemotaxis. Life Sci. 73, 1729-1740.
36. Farhadi, A., Banan, A., Fields, J. and Keshavarzian, A. (2003) Intestinal barrier: an interface between health and disease. J. Gastroenterol. Hepatol. 18, 479-497.
37. Wijeratne, S. S., Cuppett, S. L. and Schlegel, V. (2005) Hydrogen peroxide induced oxidative stress damage and antioxidant enzyme response in Caco-2 human colon cells. J. Agric. Food Chem. 53, 8768-8774.
38. Jepson, M. A. (2003) Disruption of epithelial barrier function by H2O2: distinct responses of Caco-2 and Madin-Darby canine kidney (MDCK) strains. Cell. Mol. Biol. (Noisy-legrand) 49, 101-112.
39. Kevil, C. G., Oshima, T., Alexander, B., Coe, L. L. and Alexander, J. S. (2000) H(2)O(2)-mediated permeability: role of MAPK and occludin. Am. J. Physiol. Cell. Physiol. 279, C21-C30.
40. Macek, R., Swisshelm, K. and Kubbies, M. (2003) Expression and function of tight junction associated molecules in human breast tumor cells is not affected by the Ras-MEK1 pathway. Cell. Mol. Bio.l (Noisy-le-grand) 49, 1-11.
41. Savkovic, S. D., Ramaswamy, A., Koutsouris, A. and Hecht, G. (2001) EPEC-activated ERK1/2 participate in inflammatory response but not tight junction barrier disruption. Am. J. Physiol. Gastrointest. Liver Physiol. 281, G890-G898.
42. Lui, W. Y., Lee, W. M. and Cheng, C. Y. (2003) TGF-betas: their role in testicular function and Sertoli cell tight junction dynamics. Int. J. Androl. 26, 147-160.
43. Yamamoto, T., Kojima, T., Murata, M., Takano, K., Go, M., Hatakeyama, N., Chiba, H. and Sawada, N. (2005) p38 MAP-kinase regulates function of gap and tight junctions during regeneration of rat hepatocytes. J. Hepatol. 42, 707-718.
44. Lee, J. C., Kassis, S., Kumar, S., Badger, A. and Adams, J. L. (1999) p38 mitogen-activated protein kinase inhibitors - mechanisms and therapeutic potentials. Pharmacol. Ther. 82, 389-397.
45. Kumar, S., Boehm, J. and Lee, J. C. (2003) p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases. Nat. Rev. Drug Discov. 2, 717-726.
46. Furuse, M., Fujita, K., Hiiragi, T., Fujimoto, K. and Tsukita, S. (1998) Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J. Cell Biol. 141, 1539-1550.
47. Sonoda, N., Furuse, M., Sasaki, H., Yonemura, S., Katahira, J., Horiguchi, Y. and Tsukita, S. (1999) Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier. J. Cell Biol. 147, 195-204.
48. Van Itallie, C., Rahner, C. and Anderson, J. M. (2001) Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability. J. Clin. Invest. 107, 1319-1327.
49. Hou, J., Gomes, A. S., Paul, D. L. and Goodenough, D. A. (2006) Study of claudin function by RNA interference. J. Biol. Chem. 281, 36117-36123.