Novel amino linkers enabling efficient labeling and convenient purification of amino-modified oligonucleotides

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 2, 2008, Pages 941-949

  Komatsu, Yasuo ^a   Kojima, Naoshi ^a   Sugino, Maiko ^a   Mikami, Akiko ^a   Nonaka, Ken ^b   Fujinawa, Yumi ^b   Sugimoto, Takashi ^b   Sato, Kousuke ^a   Matsubara, Kenichi ^b   Ohtsuka, Eiko ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b DNA CHIP RESEARCH INC   (Japan)

Author keywords

Amino linker; Labeling; Microarray; Nucleic acids; Oligonucleotides

Indexed keywords

AMINE; AMINO ACID; CARBAMIC ACID DERIVATIVE; HYDROGEN; METHYL GROUP; OLIGONUCLEOTIDE; REAGENT;

ACIDITY; AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; PHYSICAL CHEMISTRY; STEREOCHEMISTRY; SUPRAMOLECULAR CHEMISTRY;

AMINES; CELL LINE, TUMOR; HUMANS; MOLECULAR STRUCTURE; OLIGONUCLEOTIDE PROBES; OLIGONUCLEOTIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 38549173036     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.10.011     Document Type: Article

References (23)

1. Maskos U., and Southern E.M. Nucleic Acids Res. 20 (1992) 1675
2. Southern E.M., Case-Green S.C., Elder J.K., Johnson M., Mir K.U., Wang L., and Williams J.C. Nucleic Acids Res. 22 (1994) 1368
3. Fodor S.P., Read J.L., Pirrung M.C., Stryer L., Lu A.T., and Solas D. Science 251 (1991) 767
4. Jacobs J.W., and Fodor S.P. Trends Biotechnol. 12 (1994) 19
5. Egeland R.D., Marken F., and Southern E.M. Anal. Chem. 74 (2002) 1590
6. Okamoto T., Suzuki T., and Yamamoto N. Nat. Biotechnol. 18 (2000) 438
7. Beier M., and Hoheisel J.D. Nucleic Acids Res. 27 (1999) 1970
8. Ramakrishnan R., Dorris D., Lublinsky A., Nguyen A., Domanus M., Prokhorova A., Gieser L., Touma E., Lockner R., Tata M., Zhu X., Patterson M., Shippy R., Sendera T.J., and Mazumder A. Nucleic Acids Res. 30 (2002) e30
9. Taton T.A., Mirkin C.A., and Letsinger R.L. Science 289 (2000) 1757
10. Elghanian R., Storhoff J.J., Mucic R.C., Letsinger R.L., and Mirkin C.A. Science 277 (1997) 1078
11. Pathak S., Choi S.K., Arnheim N., and Thompson M.E. J. Am. Chem. Soc. 123 (2001) 4103
12. Raddatz S., Mueller-Ibeler J., Kluge J., Wass L., Burdinski G., Havens J.R., Onofrey T.J., Wang D., and Schweitzer M. Nucleic Acids Res. 30 (2002) 4793
13. Koch T., Jacobsen N., Fensholdt J., Boas U., Fenger M., and Jakobsen M.H. Bioconjug. Chem. 11 (2000) 474
14. Rehman F.N., Audeh M., Abrams E.S., Hammond P.W., Kenney M., and Boles T.C. Nucleic Acids Res. 27 (1999) 649
15. Epstein J.R., Lee M., and Walt D.R. Anal. Chem. 74 (2002) 1836
16. Epstein J.R., Ferguson J.A., Lee K.H., and Walt D.R. J. Am. Chem. Soc. 125 (2003) 13753
17. Agrawal S., Christodoulou C., and Gait M.J. Nucleic Acids Res. 14 (1986) 6227
18. Emson P.C., Arai H., Agrawal S., Christodoulou C., and Gait M.J. Methods Enzymol. 168 (1989) 753
19. Komatsu Y., Kojima N., Nonaka K., Fujinawa Y., Sugino M., Mikami A., Hashida J., Ohtsuka E., and Matsubara K. Nucleic Acids Symp. Ser. (2004) 21
20. Kojima N., Sugino M., Mikami A., Nonaka K., Fujinawa Y., Muto I., Matsubara K., Ohtsuka E., and Komatsu Y. Bioorg Med. Chem. Lett. 16 (2006) 5118
21. Aurup H., Tuschl T., Benseler F., Ludwig J., and Eckstein F. Nucleic Acids Res. 22 (1994) 20
22. Ogawa A., Tanaka M., Sasaki T., and Matsuda A. J. Med. Chem. 41 (1998) 5094
23. Sato K., Seio K., and Sekine M. J. Am. Chem. Soc. 124 (2002) 12715