Enhanced reactivity of amino-modified oligonucleotides by insertion of aromatic residue

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 19, 2006, Pages 5118-5121

  Kojima, Naoshi ^a   Sugino, Maiko ^a   Mikami, Akiko ^a   Nonaka, Ken ^b   Fujinawa, Yumi ^b   Muto, Isamu ^c   Matsubara, Kenichi ^b   Ohtsuka, Eiko ^a   Komatsu, Yasuo ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b DNA CHIP RESEARCH INC   (Japan)

^c HITACHI LTD   (Japan)

Author keywords

Amino modified oligonucleotide; Aromatic group; Hydrophobic interaction

Indexed keywords

ALIPHATIC COMPOUND; AROMATIC AMINE; OLIGONUCLEOTIDE; REAGENT;

AMINO ACID SYNTHESIS; ARTICLE; DNA MICROARRAY; HYDROPHOBICITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PROTEIN MODIFICATION; PROTEIN STRUCTURE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRUCTURE ANALYSIS;

AMINES; COMBINATORIAL CHEMISTRY TECHNIQUES; CROSS-LINKING REAGENTS; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDES; POLYCYCLIC HYDROCARBONS, AROMATIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33747362103     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.07.027     Document Type: Article

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