Mitochondrial toxicity and antioxidant activity of a prenylated flavonoid isolated from Dalea elegans

Chemico-Biological Interactions

Volumn 171, Issue 3, 2008, Pages 294-305

  Elingold, Igal ^a   Isollabella, M Paula ^b   Casanova, Marta B ^a   Celentano, Ana M ^b   Pérez, Cristina ^b   Cabrera, José Luis ^c   Diez, Roberto A ^b   Dubin, Marta ^a  

^a Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

Antioxidant; Flavonoids; Liver; Mitochondria; Toxicity

Indexed keywords

2' 4' DIHIDROCY 5' (1''' DIMETHYLALLYL) 6 PRENYLPINOCEMBRIN; DALEA ELEGANS EXTRACT; FLAVONOID; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG INHIBITION; DRUG STRUCTURE; LIPID PEROXIDATION; LIVER MITOCHONDRION; MICROSOME; MITOCHONDRIAL TOXICITY; NONHUMAN; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME ACTIVATION; ENZYME INHIBITORS; FABACEAE; FLAVANONES; FLAVONOIDS; HUMANS; LIPID PEROXIDATION; MALE; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANES; MOLECULAR STRUCTURE; MULTIENZYME COMPLEXES; NADH, NADPH OXIDOREDUCTASES; OXYGEN; PLANT EXTRACTS; PLANT ROOTS; PRENYLATION; PROTON-TRANSLOCATING ATPASES; RATS; RATS, WISTAR; SUCCINATE DEHYDROGENASE; TUMOR CELLS, CULTURED;

DALEA; RATTUS;

EID: 38549152876     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2007.10.005     Document Type: Article

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