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Volumn 32, Issue 24, 2007, Pages 2585-2587

Research advances in pharmacology of aucubin and aucubigenin

Author keywords

Aucubin; Mechanism of activity; Pharmacological activity

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIOXIDANT; AUCUBIGENIN; AUCUBIN; GLUCOSIDE; IRIDOID; PYRAN DERIVATIVE;

EID: 38549142634     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (28)
  • 1
    • 0000038594 scopus 로고
    • Structure of ucommiol, a new cyclopentenoid-tetraol from Eucommia ulmoides [J]
    • Bianco A, Lavarone C, Tragolo C. Structure of ucommiol, a new cyclopentenoid-tetraol from Eucommia ulmoides [J]. Tetrahedron, 1974, 30:4117.
    • (1974) Tetrahedron , vol.30 , pp. 4117
    • Bianco, A.1    Lavarone, C.2    Tragolo, C.3
  • 2
    • 0011816096 scopus 로고
    • 1-O-b-D-Glucopyranosy-leucommiol, an iridoid glucoside from Aucuba japonica[J]
    • Bemini R, Iavarone C, tragolo C. 1-O-b-D-Glucopyranosy-leucommiol, an iridoid glucoside from Aucuba japonica[J]. Phytochemistry, 1984,23:1431.
    • (1984) Phytochemistry , vol.23 , pp. 1431
    • Bemini, R.1    Iavarone, C.2    tragolo, C.3
  • 3
    • 0032465984 scopus 로고    scopus 로고
    • Liver-protective activities of aucubin derived from traditional oriental medicine[J]
    • Chang I M. Liver-protective activities of aucubin derived from traditional oriental medicine[J]. Res Commun Mol Pathol Pharmacol, 1998, 102(2) :189.
    • (1998) Res Commun Mol Pathol Pharmacol , vol.102 , Issue.2 , pp. 189
    • Chang, I.M.1
  • 4
    • 0021715796 scopus 로고
    • Aucubin; potential antidote for alpha-amanitin poisoning [J]
    • Chang L M, Yun H S, Kim Y S, et al. Aucubin; potential antidote for alpha-amanitin poisoning [J]. J Toxicol Clin Toxicol, 1984, 22(1):77.
    • (1984) J Toxicol Clin Toxicol , vol.22 , Issue.1 , pp. 77
    • Chang, L.M.1    Yun, H.S.2    Kim, Y.S.3
  • 5
    • 0020554321 scopus 로고
    • Protective activities of aucubin against carbon tetrachloride-induced liver damage in mice[J]
    • Chang L M, Ryu J C, Park Y C, et al. Protective activities of aucubin against carbon tetrachloride-induced liver damage in mice[J]. Drug Chem Toxicol, 1983, 6(5):443.
    • (1983) Drug Chem Toxicol , vol.6 , Issue.5 , pp. 443
    • Chang, L.M.1    Ryu, J.C.2    Park, Y.C.3
  • 6
    • 0035261448 scopus 로고    scopus 로고
    • Studies on the possible mechanisms of protective activity against alpha-amanitin poisoning by aucubin[J]
    • Lee D H, Chi I C, Park M S, et al. Studies on the possible mechanisms of protective activity against alpha-amanitin poisoning by aucubin[J]. Arch Pharm Res, 2001,24(1):55.
    • (2001) Arch Pharm Res , vol.24 , Issue.1 , pp. 55
    • Lee, D.H.1    Chi, I.C.2    Park, M.S.3
  • 7
    • 0028889828 scopus 로고
    • Inhibition of P-450 by aucubin; is the biological activity of aucubin due to its glutaraldehyde-like aglycone[J]
    • Bartholomeus A, Ahokas J. Inhibition of P-450 by aucubin; is the biological activity of aucubin due to its glutaraldehyde-like aglycone[J]. Toxicol Lett, 1995,80(1-3):75.
    • (1995) Toxicol Lett , vol.80 , Issue.1-3 , pp. 75
    • Bartholomeus, A.1    Ahokas, J.2
  • 8
    • 0034599389 scopus 로고    scopus 로고
    • Mechanism of covalent adduct formation of aucubin to proteins[J]
    • Kim D H, Kim B R, Kim J Y, et al. Mechanism of covalent adduct formation of aucubin to proteins[J]. Toxicol Lett, 2000, 114(1-3):181.
    • (2000) Toxicol Lett , vol.114 , Issue.1-3 , pp. 181
    • Kim, D.H.1    Kim, B.R.2    Kim, J.Y.3
  • 9
    • 0028201005 scopus 로고
    • Structural considerations on the iridoids as anti-inflammatory agents [J]
    • Recio M C, Giner R M, Manez S, et al. Structural considerations on the iridoids as anti-inflammatory agents [J]. Planta Med, 1994, 60(3):232.
    • (1994) Planta Med , vol.60 , Issue.3 , pp. 232
    • Recio, M.C.1    Giner, R.M.2    Manez, S.3
  • 10
    • 0034039525 scopus 로고    scopus 로고
    • Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems[J]
    • Bermejo Benito P, Diaz Lanza A M, Silvan Sen A M, et al. Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems[J]. Planta Med, 2000,66(4):324.
    • (2000) Planta Med , vol.66 , Issue.4 , pp. 324
    • Bermejo Benito, P.1    Diaz Lanza, A.M.2    Silvan Sen, A.M.3
  • 11
    • 0036037498 scopus 로고    scopus 로고
    • Inhibition of TNF-alpha and IL-6 production by Aucubin through blockade of NF-kappa B activation RBL-2H3 mast cells[J]
    • Jeong H J, Koo H N, Na H J, et al. Inhibition of TNF-alpha and IL-6 production by Aucubin through blockade of NF-kappa B activation RBL-2H3 mast cells[J]. Cytokine, 2002,18(5):252.
    • (2002) Cytokine , vol.18 , Issue.5 , pp. 252
    • Jeong, H.J.1    Koo, H.N.2    Na, H.J.3
  • 12
    • 23844485308 scopus 로고    scopus 로고
    • The NF-kappaB signaling pathway in human genetic diseases[J]
    • Coutois G. The NF-kappaB signaling pathway in human genetic diseases[J]. Cell Mol Life Sci, 2005,62 (15): 1682.
    • (2005) Cell Mol Life Sci , vol.62 , Issue.15 , pp. 1682
    • Coutois, G.1
  • 13
    • 33744945025 scopus 로고    scopus 로고
    • Exploring the positive and negative consequences of NF-kappaB inhibition for the treatment of human disease [J]
    • Fraser C C. Exploring the positive and negative consequences of NF-kappaB inhibition for the treatment of human disease [J]. Cell Cycle, 2006, 5 (11): 1160.
    • (2006) Cell Cycle , vol.5 , Issue.11 , pp. 1160
    • Fraser, C.C.1
  • 14
    • 33749036594 scopus 로고    scopus 로고
    • NF-kappa B signaling; pros and cons of altering NF-kappaB as a therapeutic approach [J]
    • Egan L J, Toruner. NF-kappa B signaling; pros and cons of altering NF-kappaB as a therapeutic approach [J]. Ann N Y Acad Sci, 2006,1072:114.
    • (2006) Ann N Y Acad Sci , vol.1072 , pp. 114
    • Egan, L.J.1    Toruner2
  • 15
    • 4444384632 scopus 로고    scopus 로고
    • Anti-inflammatory activity of aucubin by inhibition of tumor necrosis factor-alpha production in RAW 264. 7 cells[J]
    • Park K S, Chang I M. Anti-inflammatory activity of aucubin by inhibition of tumor necrosis factor-alpha production in RAW 264. 7 cells[J]. Planta Med, 2004, 70(8) :778.
    • (2004) Planta Med , vol.70 , Issue.8 , pp. 778
    • Park, K.S.1    Chang, I.M.2
  • 16
    • 24944483720 scopus 로고    scopus 로고
    • Protective effects of aucubin isolated from Eucommia ulmoides against UVB-induced oxidative stress in human skin fibroblasts[J]
    • Ho J N, Lee Y H, Park J S, et al. Protective effects of aucubin isolated from Eucommia ulmoides against UVB-induced oxidative stress in human skin fibroblasts[J]. Biol Pharm Bul, 2005, 28 (7):1244.
    • (2005) Biol Pharm Bul , vol.28 , Issue.7 , pp. 1244
    • Ho, J.N.1    Lee, Y.H.2    Park, J.S.3
  • 17
    • 0033956766 scopus 로고    scopus 로고
    • The promoting effect of eucommiol from Eucommiae cortex on collagen synthesis [J]
    • Li Y, Kamo S, Metori K, et al. The promoting effect of eucommiol from Eucommiae cortex on collagen synthesis [J]. Biol Pharm Bull, 2000, 23(1):54.
    • (2000) Biol Pharm Bull , vol.23 , Issue.1 , pp. 54
    • Li, Y.1    Kamo, S.2    Metori, K.3
  • 18
    • 0032434309 scopus 로고    scopus 로고
    • The promoting effects of genipoaidic acid and aucubin in Eucommia ulmoides oliver leaves on collagen synthesis[J]
    • Li Y, Sato T, Metork K, et al. The promoting effects of genipoaidic acid and aucubin in Eucommia ulmoides oliver leaves on collagen synthesis[J]. Biol Pharm Bull, 1998, 21 ( 12):1306.
    • (1998) Biol Pharm Bull , vol.21 , Issue.12 , pp. 1306
    • Li, Y.1    Sato, T.2    Metork, K.3
  • 19
    • 3042601244 scopus 로고    scopus 로고
    • Effects of Eucommiae cortex on osteoblaat-like cell proliferation and osteoclast inhibition [J]
    • Ha H, Ho J, Shin S, et al. Effects of Eucommiae cortex on osteoblaat-like cell proliferation and osteoclast inhibition [J]. Arch Pharm Res, 2003, 26(11):929.
    • (2003) Arch Pharm Res , vol.26 , Issue.11 , pp. 929
    • Ha, H.1    Ho, J.2    Shin, S.3
  • 20
    • 0030014491 scopus 로고    scopus 로고
    • Neuritogenic effect of natural iridoid compounds on PC12h cells and its possible relation to signaling protein[J]
    • Yamazaki M, Chiba K, Mohri T, et al. Neuritogenic effect of natural iridoid compounds on PC12h cells and its possible relation to signaling protein[J]. Biol Pharm Bull, 1996,19(6):791.
    • (1996) Biol Pharm Bull , vol.19 , Issue.6 , pp. 791
    • Yamazaki, M.1    Chiba, K.2    Mohri, T.3
  • 21
    • 0028558824 scopus 로고
    • Promotion of neuronal differentiation of PC12h cells by natural lignans and iridoids[J]
    • Yamazaki M, Hirota K, Chiba K, et al. Promotion of neuronal differentiation of PC12h cells by natural lignans and iridoids[J]. Biol Pharm Bull, 1994, 17(12):1604.
    • (1994) Biol Pharm Bull , vol.17 , Issue.12 , pp. 1604
    • Yamazaki, M.1    Hirota, K.2    Chiba, K.3
  • 22
    • 0028051407 scopus 로고    scopus 로고
    • Ortiz D E, Urbina A V, Martin M L, et al. In vitro antispasmodic activity of peracetylated penstemonoeide, aucubin and catalpol [J]. Planta Med, 1994,60(6)-512.
    • Ortiz D E, Urbina A V, Martin M L, et al. In vitro antispasmodic activity of peracetylated penstemonoeide, aucubin and catalpol [J]. Planta Med, 1994,60(6)-512.
  • 23
    • 0041381134 scopus 로고    scopus 로고
    • Antileukemic activity of selected natural products in Taiwan [J]
    • Chiang LC, Chiang W, Chang M Y, et al. Antileukemic activity of selected natural products in Taiwan [J]. Am J Chin Med, 2003,31(1):37.
    • (2003) Am J Chin Med , vol.31 , Issue.1 , pp. 37
    • Chiang, L.C.1    Chiang, W.2    Chang, M.Y.3
  • 24
    • 12844282019 scopus 로고    scopus 로고
    • Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of Scrophuiaria Upidota roots[J]
    • Tasdemir D, Guner N D, Perozzo R, et al. Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of Scrophuiaria Upidota roots[J]. Phytochemistry, 2005, 66(3):355.
    • (2005) Phytochemistry , vol.66 , Issue.3 , pp. 355
    • Tasdemir, D.1    Guner, N.D.2    Perozzo, R.3
  • 25
    • 0041379649 scopus 로고    scopus 로고
    • Immunomodulatory activities of flavonoids, monoterpenoids, triterpenoids, iridoid glycosides and phenolic compounds of Plantago species [J]
    • Chiang L C, Ng L T, Chiang W, et al. Immunomodulatory activities of flavonoids, monoterpenoids, triterpenoids, iridoid glycosides and phenolic compounds of Plantago species [J]. Planta Med, 2003, 69(7):600.
    • (2003) Planta Med , vol.69 , Issue.7 , pp. 600
    • Chiang, L.C.1    Ng, L.T.2    Chiang, W.3
  • 26
    • 0035206872 scopus 로고    scopus 로고
    • Constituents and pharmacological effects of Eucommia and Suenan ginseng[ J]
    • Deyama T, Nishibe S, Nakazawa Y. Constituents and pharmacological effects of Eucommia and Suenan ginseng[ J]. Acta Pharmacol Sin, 2001, 22(12):1057.
    • (2001) Acta Pharmacol Sin , vol.22 , Issue.12 , pp. 1057
    • Deyama, T.1    Nishibe, S.2    Nakazawa, Y.3
  • 28
    • 20344370463 scopus 로고    scopus 로고
    • Synthesis and cytotoxicity of a novel iridoid glucoside derived from aucubin[J]
    • Mouries C, Rakotondramasy V C, Libot F, et al. Synthesis and cytotoxicity of a novel iridoid glucoside derived from aucubin[J]. Chem Biodivers, 2005,2(5):695.
    • (2005) Chem Biodivers , vol.2 , Issue.5 , pp. 695
    • Mouries, C.1    Rakotondramasy, V.C.2    Libot, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.