Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems

Planta Medica

Volumn 66, Issue 4, 2000, Pages 324-328

  Benito, Paulina Bermejo ^a   Lanza, Ana María Díaz ^b   Sen, Ana Maria Silván ^a   De Santos Galindez, Javier ^b   Matellano, Lidia Fernandez ^b   Gómez, Aurora Sanz ^a   Martínez, María José Abad ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

Anti inflammatory activity; Iridoids; LTC4; PGE2; Scrophularia scorodonia; Scrophulariaceae; TXB2

Indexed keywords

8 ACETYLHARPAGIDE; ARACHIDONIC ACID; AUCUBIN; CALCIUM IONOPHORE; HARPAGIDE; HARPAGOSIDE; IBUPROFEN; IRIDOID; LEUKOTRIENE C4; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; STRUCTURE ACTIVITY RELATION; THROMBOCYTE;

ANIMALS; ARACHIDONIC ACID; CARBOHYDRATE SEQUENCE; FEMALE; GLYCOSIDES; HUMANS; MALE; MICE; MOLECULAR SEQUENCE DATA; PLANTS;

ANIMALIA; SCROPHULARIA; SCROPHULARIA SCORODONIA; SCROPHULARIACEAE;

EID: 0034039525     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-8549     Document Type: Article

References (20)

1. 1 Kajimoto T, Hidaka M, Shoyama K, Hohara T. Iridoids from Scrophularia ningpoensis. Phytochemistry 1989; 28: 2701-4
2. 2 Giner RM, Sanz MJ, Ferrandiz ML, Recio MC, Terencio MC, Rios JL. Topical anti-inflammatory activity of some iridoids and phenylpropanoids. Planta Med. 1991; 57: A53
3. 3 Boros CA, Stermitz FR. Iridoids. An updated review. J. Nat. Prod. 1990; 53: 1055-147
4. 4 Miyagoshi M, Amagaya S, Ogihara Y. Choleretic actions of iridoids compounds. J. PharmacobioDyn. 1988; 11: 186-90
5. 5 Breschi MC, Martinotti E, Catalano S, Falmini G, Morelli I, Pagni AM. Vasoconstrictor activity of 8-0-acetylharpagide from Ajuga reptans. J. Nat. Prod. 1992; 55: 1145-8
6. 6 Chang IM, Ryu JC, Park IC, Yun HS, Yang KH. Protective activities of aucubin against carbon tetrachloride-induced liver damage in mice. Drug Chem. Toxicol. 1983; 6: 443-53
7. 7 Tan GT, Miller JF, Kinghorn AD, Hughes SH, Pezzuto JM. HIV-1 and HIV-2 reverse transcriptases; a comparative study of sensitivity to inhibition by selected natural products. Biochem. Biophys. Res. Commun. 1992; 185: 370-8
8. 8 Jewers K, Coppen JJW, Manchanda AH, Paisley HM, Castillo A. Some biologically active lactones of Allamanda cathartica. Pahlavi Medical J. 1975; 6: 52-62
9. 9 Lanhers MC, Fleurentin J, Mortier F, Vinche A, Younos C. Anti-inflammatory and analgesic effects of an aqueous extract of Harpagophytum procumbens. Planta Med. 1992; 58: 117-23
10. 10 Recio MC, Giner RM, Mañez S, Rios JL. Structural considerations on the iridoids as anti-inflammatory agents. Planta Med. 1994; 60: 232-4
11. 11 Fernandez L, Diaz AM, Ollivier E, Faure R, Balansard G. An iridoid diglycoside isolated from Scrophularia scorodonia. Phytochemistry 1995; 40: 1569-71
12. 12 Fernandez-Matellano L, Ollivier E, Diaz-Lanza AM, Faure R, Balansard G. Iridoids from Scrophularia scorodonia. Planta Med. 1995; 61: 63
13. 13 De Santos J, Fernandez L, Diaz AM, Rubio B, Ollivier E, Faure R, Balansard G. Catalpol glycosides from Scrophularia scorodonia. Pharmazie 1998; 53: 4
14. 14 Bickel D, Röder T, Bestmann MJ, Brune K. Identification and characterization of inhibitors of peptidoleukotriene-synthesis from Petasites hybridus. Planta Med. 1994; 60: 318-22
15. 1-histamine receptor antagonist dilthiaden inhibits stimulated platelet aggregation, malondialdehyde formation and thromboxane production in vitro. Inflamm. Res. 1995; 44: S14-5
16. 4 and the COLO 320 cell lines. Planta Med. 1994; 60: 434-7
17. 4 using acetylcholinesterase. Methods Enzymol. 1990; 187: 82-9
18. 2 release and enhanced cell proliferation induced by the phorbol ester TPA in a murine epidermal cell line. Cancer Lett. 1981; 11: 191-8
19. 19 Williams JD, Czop JK, Austen KF. Release of leukotriene by human monocytes on stimulation of their phagocytic receptor for particulate activators. J. Immunol. 1984; 132: 3034-40
20. 20 Funk CD, Kennedy ME, Pong AS, Fitzgerald GA. Human platelet-erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression and gene chromosomal assignement. FASEB J. 1991; 5: 2304-12