Flurazepam inhibits the P-glycoprotein transport function: An insight to revert multidrug-resistance phenotype

European Journal of Pharmacology

Volumn 581, Issue 1-2, 2008, Pages 30-36

  Lima, Sofia A C ^a   Tavares, Joana ^b   Gameiro, Paula ^a   de Castro, Baltazar ^a   Cordeiro da Silva, Anabela ^b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

ATPase activity; Benzodiazepines; Daunorubicin accumulation; Daunorubicin efflux; KB V1 cell; P glycoprotein inhibitor

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BENZODIAZEPINE DERIVATIVE; BROMAZEPAM; CHLORDIAZEPOXIDE; DAUNORUBICIN; DIAZEPAM; FLURAZEPAM; GLYCOPROTEIN P; VANADIC ACID;

ARTICLE; CELL LEVEL; COLORIMETRY; CONTROLLED STUDY; DRUG BINDING; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; GEOMETRY; HUMAN; HUMAN CELL; HYDROLYSIS; MULTIDRUG RESISTANCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TRANSPORT; PROTEOLIPOSOME;

BENZODIAZEPINES; CELL LINE, TUMOR; CELL SURVIVAL; DAUNORUBICIN; DRUG RESISTANCE, MULTIPLE; FLURAZEPAM; HUMANS; P-GLYCOPROTEIN; PHENOTYPE;

EID: 38549114108     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.11.045     Document Type: Article

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