Sphingosine-1-phosphate and endothelin-1 induce the expression of rgs16 protein in cardiac myocytes by transcriptional activation of the rgs16 gene

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 376, Issue 5, 2008, Pages 363-373

  Stuebe, Sabine ^a   Wieland, Thomas ^b   Kraemer, Elisabeth ^a   Stritzky, Alexandra V ^a   Schroeder, Diana ^a   Seekamp, Sünje ^a   Vogt, Andreas ^b   Chen, Ching Kang ^c   Patten, Monica ^a  

^a UNIVERSITY HEART CENTER HAMBURG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Gene expression; RGS proteins; Transcriptional regulation; YY1

Indexed keywords

5 (4 PHENYL 5 TRIFLUOROMETHYL 2 THIENYL) 3 (3 TRIFLUOROMETHYLPHENYL) 1,2,4 OXADIAZOLE; CLOSTRIDIUM DIFFICILE TOXIN B; ENDOTHELIN 1; LUCIFERASE; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PERTUSSIS TOXIN; PROTEIN; RAC1 PROTEIN; RGS16 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SPHINGOSINE 1 PHOSPHATE; TRANSCRIPTION FACTOR YY1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SYNTHESIS; FETAL CALF SERUM; GENE; GENE ACTIVATION; GENE IDENTIFICATION; GENE SEQUENCE; GENE VECTOR; HEART MUSCLE CELL; MOLECULAR CLONING; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN EXPRESSION; RAT; RGS16 GENE; TRANSCRIPTION INITIATION;

ANIMALS; ANIMALS, NEWBORN; BACTERIAL PROTEINS; BACTERIAL TOXINS; CATTLE; CELLS, CULTURED; ENDOTHELIN-1; FETAL BLOOD; GENE EXPRESSION REGULATION; LUCIFERASES; LYSOPHOSPHOLIPIDS; MICE; MYOCYTES, CARDIAC; PERTUSSIS TOXIN; PROMOTER REGIONS (GENETICS); RAC1 GTP-BINDING PROTEIN; RATS; RGS PROTEINS; RHOA GTP-BINDING PROTEIN; SPHINGOSINE; TRANSCRIPTION, GENETIC; YY1 TRANSCRIPTION FACTOR;

EID: 38549109742     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-007-0214-2     Document Type: Article

References (41)

1. Appert-Collin A, Cotecchia S, Nenniger-Tosato M, Pedrazzini T, Diviani D (2007) The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy. Proc Natl Acad Sci USA 104:10140-10145
2. Arai K, Maruyama Y, Nishida M, Tanabe S, Takagahara S, Kozasa T, Mori Y, Nagao T, Kurose H (2003) Differential requirement of G alpha12, G alpha13, G alphaq, and G beta gamma for endothelin-1-induced c-Jun NH2-terminal kinase and extracellular signal-regulated kinase activation. Mol Pharmacol 63:478-488
3. Barth H, Hofmann F, Olenik C, Just I, Aktories K (1998) The N-terminal part of the enzyme component (C2I) of the binary clostridium botulinum C2 toxin interacts with the binding component C2II and functions as a carrier system for a Rho ADP-ribosylating C3-like fusion toxin. Infect Immun 66:1364-1369
4. Booden M, Siderovski D, Der C (2002) Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA. Mol Cell Biol 22:4053-4061
5. Clerk A, Pahm FH, Fuller SJ, Sahai E, Aktories K, Marais R, Marshall C, Sugden PH (2001) Regulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1. Mol Cell Biol 21:1173-1184
6. Dohlman H, Thorner J (1997) RGS proteins and signaling by heterotrimeric G proteins. J Biol Chem 272:3871-3874
7. 3H]- dihydrosphingosine-1-phosphate. Br J Pharmacol 142:851-860
8. Fu Y, Huang X, Zhong H, Mortensen RM, D'Alecy LG, Neubig RR (2006) Endogenous RGS proteins and Gα subtypes differentially control muscarinic and adenosine-mediated chronotropic effects. Circ Res 98:659-666
9. Fukushima N, Ishii I, Contros JJA, Weiner JA, Chun J (2001) Lysophospholipid receptors. Ann Rev Pharmacol Toxicol 41:507-534
10. Gualberto A, lePage D, Pons G, Mader S, Park K, Atchison M, Walsh K (1992) Functional antagonism between YY1 and the serum response factor. Mol Cell Biol 12:4209-4214
11. Hao J, Michalek C, Zhang W, Zhu M, Xu X, Mende U (2006) Regulation of cardiomyocyte signaling by RGS proteins: differential selectivity towards G proteins and susceptibility to regulation. J Mol Cell Cardiol 41:51-61
12. Hill C, Wynne J, Treisman R (1995) The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell 81:1159-1170
13. Jo E, Sanna MG, Gonzalez-Cabrera PJ, Thangada S, Tigyi G, Osborne DA, Hla T, Parrill AL, Rosen H (2005) S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate. Chem Biol 12:703-715
14. Just I, Selzer J, Wilm M, von Eichel-Streiber C, Mann M, Aktories K (1995) Glucosylation of Rho proteins by Clostridium difficile toxin B. Nature 375:500-503
15. Kardestuncer T, Wu H, Lim AL, Neer EJ (1998) Cardiac myocytes express mRNA for ten RGS proteins: changes in RGS mRNA expression in ventricular myocytes and cultured atria. FEBS Lett 438:285-288
16. Lee TC, Shi Y, Schwartz RJ (1992) Displacement of BrdUrd-induced YY1 by serum response factor activates skeletal α-actin transcription in embryonic myoblasts. Proc Natl Acad Sci USA 89:9814-9818
17. Lutz S, Freichel-Blomquist A, Rumenapp U, Schmidt M, Jakobs KH, Wieland T (2004) p63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same gene. Naunyn Schmiedeberg's Arch Pharmacol 369:540-546
18. Lutz S, Freichel-Blomquist A, Yang Y, Rumenapp U, Jakobs KH, Schmidt M, Wieland T (2005) The guanine nucleotide exchange factor p63RhoGEF-a specific link between Gq/11-coupled receptor signaling and RhoA. J Biol Chem 280:11134-11139
19. Mittmann C, Chung C-H, Höppner G, Michalek C, Nose M, Schüler C, Schuh A, Eschenhagen T, Weil J, Pieske B, Hirt S, Wieland T (2002) Expression of ten RGS proteins in human myocardium: functional characterization of an upregulation of RGS4 in heart failure. Cardiovasc Res 55:778-786
20. Oral H, Dorn GW, Mann DL (1997) Sphingosine mediates the immediate negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian cardiac myocyte. J Biol Chem 272:4836-4842
21. Panetta R, Guo Y, Magder S, Greenwood MT (1999) Regulators of G-protein signaling (RGS) 1 and 16 are induced in response to bacterial lipopolysaccharide and stimulate c-fos promoter expression. Biochem Biophys Res Com 259:550-556
22. Patten M, Hartogensis WE, Long CS (1996) Interleukin-1β is a negative transcriptional regulator of α1-adrenergic induced gene expression in cultured cardiac myocytes. J Biol Chem 271:21134-21141
23. Patten M, WeiZhong W, Aminololama-Shakeri S, Burson M, Long CS (2000) IL-1β increases abundance and activity of the negative transcriptional regulator Yin Yang-1 (YY1) in neonatal rat cardiac myocytes. J Mol Cell Cardiol 32:1341-1352
24. Patten M, Bünemann J, Thoma B, Krämer E, Thoenes M, Mittmann C, Wieland T (2002) Endotoxin induces desensitization of cardiac endothelin-1 receptor signaling by increased expression of RGS4 and RGS16. Cardiovasc Res 53:159-164
25. Patten M, Stübe S, Thoma B, Wieland T (2003) Interleukin-1β mediates endotoxin- and tumor necrosis α-induced RGS16 protein expression in cultured cardiac myocytes. Naunyn-Schmiedeberg's Arch Pharmacol 368:360-365
26. Ren X, Schwartz MA (2000) Determination of GTP loading on Rho. Methods Enzymol 325:264-272
27. Resch ZT, Oxvig C, Bale LK, Conover CA (2006) Stress-activated signaling pathways mediate the stimulation of pregnancy-associated plasma protein-A expression in cultured human fibroblasts. Endocrinology 147:885-890
28. Riddle E, Schwartzman R, Bond M, Insel P (2005) Multi-tasking RGS proteins in the heart: the next therapeutic target? Circ Res 96:401-411
29. Rogers JH, Tamirisa P, Kovacs A, Weinheimer C, Courtois M, Blumer KJ, Kelly DP, Muslin AJ (1999) RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload. J Clin Invest 104:567-576
30. Rubanyi GM, Polokoff MA (1994) Endothelins: molecular biology, biochemistry, pharmacology, physiology and pathophysiology. Pharmacol Rev 46:325-415
31. Shrivastava A, Calame K (1994) An analysis of genes regulated by the multifunctional transcriptional regulator Yin Yang-1. Nucleic Acids Res 22:5151-5155
32. Takigawa M, Sakurai T, Kasuya Y, Abe A, Masaki T, Goto K (1995) Molecular identification of guanine-nucleotide-binding regulatory proteins which couple to endothelin receptors. Eur J Biochem 228:102-108
33. Thirunavukkarasu K, Halladay DL, Miles RR, Geringer CD, Onyia JE (2002) Analysis of regulator of G-protein signaling-2 (RGS2) expression and function in osteoblastic cells. J Cell Biochem 85:837-850
34. Ueda H, Morishita R, Yamauchi J, Itoh H, Kato K, Asano T (2001) Regulation of Rac and Cdc42 pathways by G(i) during lysophosphatidic acid-induced cell spreading. J Biol Chem 276:6846-6852
35. Wieland T, Chen CK (1999) Regulators of G-protein signalling: a novel protein family involved in timely deactivation and desensitization of signalling via heterotrimeric G proteins. Naunyn-Schmiedeberg's Arch Pharmacol 360:14-26
36. Wieland T, Mittmann C (2003) Regulators of G-protein signalling: multifunctional proteins with impact on signalling in the cardiovascular system. Pharmacol Ther 97:95-115
37. Wieland T, Lutz S, Chidiac P (2007) Regulators of G protein signalling: a spotlight on emerging functions in the cardiovascular system. Curr Opin Pharmacol 7:201-207
38. q/11 signaling by RGS2 protein exacerbates cardiomyocyte hypertrophy. J Biol Chem 281:5811-5820
39. Zimmermann WH, Fink C, Kralisch D, Remmers U, Weil J, Eschenhagen T (2000) Three-dimensional engineered heart tissue from neonatal rat cardiac myocytes. Biotechnol Bioeng 68:106-114
40. Zondag GC, Postma FR, Etten IV, Verlaan I, Moolenaar WH (1998) Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1. Biochem J 330:605-609
41. 1-adrenergic activation in cultured ventricular myocytes. Cell Signal 18:1655-1663