Assessment of the genotoxicity of the rat carcinogen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in rat liver epithelial cells in vitro

Toxicology in Vitro

Volumn 22, Issue 2, 2008, Pages 535-540

  Maki Paakkanen J ^a   Hakulinen, P ^a  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

DNA damage; Drinking water; Gene mutation; Hprt locus; MX; Single cell gel Comet assay; WB F344 cells

Indexed keywords

3 CHLORO 4 (DICHLOROMETHYL) 5 HYDROXY 2(5H)FURANONE; CARCINOGEN; DNA; FURANONE DERIVATIVE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; PHOSPHATE BUFFERED SALINE; TIOGUANINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARCINOGENICITY; CELL COMMUNICATION; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; EPITHELIUM CELL; GAP JUNCTION; GENE LOCUS; GENE MUTATION; GENOTOXICITY; IN VITRO STUDY; LIVER; LIVER CARCINOGENESIS; LIVER TOXICITY; MUTANT; NONHUMAN; RAT; TUMOR PROMOTION;

ANIMALS; CARCINOGENS; CELL LINE; CELL SURVIVAL; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; FURANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LIVER; MUTAGENS; MUTATION; RATS; RATS, INBRED F344;

RATTUS;

EID: 38549102661     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.10.001     Document Type: Article

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