메뉴 건너뛰기




Volumn 47, Issue 5, 2008, Pages 898-901

Probing inducible nitric oxide synthase with a pterin-ruthenium(II) sensitizer wire

Author keywords

Electron transfer; Metalloenzymes; Nitric oxide synthase; Ruthenium; Sensitizers

Indexed keywords

CHEMICAL BONDS; ELECTRON TRANSPORT PROPERTIES; MOLECULAR DYNAMICS; RUTHENIUM COMPOUNDS;

EID: 38549093580     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200703743     Document Type: Article
Times cited : (11)

References (26)
  • 15
    • 0242407670 scopus 로고    scopus 로고
    • see Supporting Information for full reference
    • a) P. Kotsonis et al., J. Biol. Chem. 2001, 276, 49133-49141 (see Supporting Information for full reference);
    • (2001) J. Biol. Chem , vol.276 , pp. 49133-49141
    • Kotsonis, P.1
  • 19
    • 85178368190 scopus 로고    scopus 로고
    • Q. Yao, W. Pfleiderer, Helv. Chim. Acta 2003, 86, 1-12. Pterins are notoriously insoluble; we have found that the DMF dimethyl acetal protecting group is far superior to many others in that it allows further chemistry to be carried out, but is still sufficiently labile, in contrast to amide and thiol protecting groups.
    • Q. Yao, W. Pfleiderer, Helv. Chim. Acta 2003, 86, 1-12. Pterins are notoriously insoluble; we have found that the DMF dimethyl acetal protecting group is far superior to many others in that it allows further chemistry to be carried out, but is still sufficiently labile, in contrast to amide and thiol protecting groups.
  • 20
    • 85178329118 scopus 로고    scopus 로고
    • A more direct approach to the 4-O species was attempted using Mitsunobu chemistry (see ref. [11]); however, it was found that this route also led to a combination of O- and N-alkylated species, but with an overall lower yield.
    • A more direct approach to the 4-O species was attempted using Mitsunobu chemistry (see ref. [11]); however, it was found that this route also led to a combination of O- and N-alkylated species, but with an overall lower yield.
  • 21
    • 85178367647 scopus 로고    scopus 로고
    • The amide was used instead of the carboxylic acid to prevent any undesired reactions with the protein
    • The amide was used instead of the carboxylic acid to prevent any undesired reactions with the protein.
  • 25
    • 85178362417 scopus 로고    scopus 로고
    • Förster energy transfer calculations were performed as described in ref. [3d]. See Supporting Information for further details.
    • Förster energy transfer calculations were performed as described in ref. [3d]. See Supporting Information for further details.
  • 26
    • 85178322081 scopus 로고    scopus 로고
    • 4B or synthetic pterin analogues. See refs [7b, 15], and J. Wang, D. J. Stuehr, D. L. Rousseau, Biochemistry 1995, 34, 7080-7087.
    • 4B or synthetic pterin analogues. See refs [7b, 15], and J. Wang, D. J. Stuehr, D. L. Rousseau, Biochemistry 1995, 34, 7080-7087.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.