메뉴 건너뛰기




Volumn 24, Issue 1, 2008, Pages 61-67

Molecular markers in transitional cell carcinoma of the bladder: New insights into mechanisms and prognosis

Author keywords

Angiogenesis; Biomarkers; Bladder cancer; Carcinogenesis; Cell cycle regulators; Loss of heterozygosity; Molecular markers; Prognosis; Urothelial carcinoma

Indexed keywords


EID: 38549090082     PISSN: 09701591     EISSN: None     Source Type: Journal    
DOI: 10.4103/0970-1591.38606     Document Type: Article
Times cited : (5)

References (85)
  • 3
    • 0026636646 scopus 로고
    • Naturalhistory of superficial bladder cancer: Prognosticfeatures and long-term disease course
    • Heney NM. Naturalhistory of superficial bladder cancer: Prognosticfeatures and long-term disease course. Urol Clin North Am 1992;19:429-33.
    • (1992) Urol Clin North Am , vol.19 , pp. 429-433
    • Heney, N.M.1
  • 4
    • 0029042453 scopus 로고
    • The relationship among multiple recurrences, progression and prognosis of patients with stages ta and T1 transitional cell cancer of the bladder followed for at least 20 years
    • Holmang S, Hedelin H, Anderstrom C, Johansson SL The relationship among multiple recurrences, progression and prognosis of patients with stages ta and T1 transitional cell cancer of the bladder followed for at least 20 years. JUrol 1995;153:1823-7.
    • (1995) JUrol , vol.153 , pp. 1823-1827
    • Holmang, S.1    Hedelin, H.2    Anderstrom, C.3    Johansson, S.L.4
  • 5
    • 1242306596 scopus 로고    scopus 로고
    • Survival rates after radical cystectomy according to tumor stage of bladder carcinoma at first presentation
    • May M, Helke C, Nitzke T, Vogler H, Hoschke B. Survival rates after radical cystectomy according to tumor stage of bladder carcinoma at first presentation. Urol Int 2004;72:103-11.
    • (2004) Urol Int , vol.72 , pp. 103-111
    • May, M.1    Helke, C.2    Nitzke, T.3    Vogler, H.4    Hoschke, B.5
  • 6
    • 0028036255 scopus 로고    scopus 로고
    • rd, Ohneseit PR Gonzalez-Zulueta M, Esrig D, Miyao N, Tsai YC, et al. Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res 1994;54:784-8.
    • rd, Ohneseit PR Gonzalez-Zulueta M, Esrig D, Miyao N, Tsai YC, et al. Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res 1994;54:784-8.
  • 7
    • 25444467767 scopus 로고    scopus 로고
    • Urothelial tumorigenesis: Atale of divergent pathways
    • Wu XR. Urothelial tumorigenesis: Atale of divergent pathways. Nat Rev Cancer 2005;5:713-25.
    • (2005) Nat Rev Cancer , vol.5 , pp. 713-725
    • Wu, X.R.1
  • 8
    • 33644868287 scopus 로고    scopus 로고
    • Knowles MA Molecular subtypes of bladder cancer: Jekyll and hyde or chalk and cheese? Carcinogenesis 2006;27:361-73.
    • Knowles MA Molecular subtypes of bladder cancer: Jekyll and hyde or chalk and cheese? Carcinogenesis 2006;27:361-73.
  • 9
    • 33644841931 scopus 로고    scopus 로고
    • Genetic alterations in urothelial bladder carcinoma: An updated review
    • Mhawech-Fauceglia P, Cheney BT, Schwaller J. Genetic alterations in urothelial bladder carcinoma: An updated review. Cancer 2006;106:1205-16.
    • (2006) Cancer , vol.106 , pp. 1205-1216
    • Mhawech-Fauceglia, P.1    Cheney, B.T.2    Schwaller, J.3
  • 10
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 11
    • 0032828684 scopus 로고    scopus 로고
    • Bladder cancer clinical guidelines panel summary report on the management of nonmuscle invasive bladder cancer (stages ta, T1 and TIS)
    • Smith JA Jr, Labasky SF, Cockett AT, Fracchia JA, Montie JE, Rowland RG. Bladder cancer clinical guidelines panel summary report on the management of nonmuscle invasive bladder cancer (stages ta, T1 and TIS). J Urol 1999;162:1697-701.
    • (1999) J Urol , vol.162 , pp. 1697-1701
    • Smith Jr, J.A.1    Labasky, S.F.2    Cockett, A.T.3    Fracchia, J.A.4    Montie, J.E.5    Rowland, R.G.6
  • 12
    • 33846581566 scopus 로고    scopus 로고
    • Chemotherapy for bladder cancer: Treatment guidelines for neoadjuvant chemotherapy, bladder preservation, adjuvant chemotherapy and metastatic cancer
    • Sternberg CN, Donat SM, Bellmunt J, Millikan RE, Stadler W, De Mulder P. et al. Chemotherapy for bladder cancer: Treatment guidelines for neoadjuvant chemotherapy, bladder preservation, adjuvant chemotherapy and metastatic cancer. Urology 2007;69:62-79.
    • (2007) Urology , vol.69 , pp. 62-79
    • Sternberg, C.N.1    Donat, S.M.2    Bellmunt, J.3    Millikan, R.E.4    Stadler, W.5    De Mulder, P.6
  • 13
    • 30044432091 scopus 로고    scopus 로고
    • Management of stage T1 tumors of the bladder: International consensus panel
    • Nieder AM, Brausi M, Lamm D, O'Donnell M, Tomita K, Woo H. et al. Management of stage T1 tumors of the bladder: International consensus panel. Urology 2005;66:108-25.
    • (2005) Urology , vol.66 , pp. 108-125
    • Nieder, A.M.1    Brausi, M.2    Lamm, D.3    O'Donnell, M.4    Tomita, K.5    Woo, H.6
  • 14
    • 8344280644 scopus 로고    scopus 로고
    • Evaluation of ZD1839 for advanced transitional cell carcinoma (TCC) of the urothelium: A Southwest Oncology Group trial
    • Petrylak D, Faulkner JR, Van Veldhuizen PJ. Evaluation of ZD1839 for advanced transitional cell carcinoma (TCC) of the urothelium: A Southwest Oncology Group trial. Proc Am Soc Clin Oncol 2003;22:403.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 403
    • Petrylak, D.1    Faulkner, J.R.2    Van Veldhuizen, P.J.3
  • 15
    • 0024399684 scopus 로고    scopus 로고
    • Weinberg RA Oncogenes, antioncogenes and the molecular bases of multistep carcinogenesis. Cancer Res 1989;49:3713-21.
    • Weinberg RA Oncogenes, antioncogenes and the molecular bases of multistep carcinogenesis. Cancer Res 1989;49:3713-21.
  • 17
    • 20844450906 scopus 로고    scopus 로고
    • Deletions of chromosomes 9 and 8p in histologically normal urothelium of patients with bladder cancer
    • Stoehr R, Zietz S, Burger M, Filbeck T, Denzinger S, Obermann EC, et al. Deletions of chromosomes 9 and 8p in histologically normal urothelium of patients with bladder cancer. Eur Urol 2005;47:58-63.
    • (2005) Eur Urol , vol.47 , pp. 58-63
    • Stoehr, R.1    Zietz, S.2    Burger, M.3    Filbeck, T.4    Denzinger, S.5    Obermann, E.C.6
  • 18
    • 0037222796 scopus 로고    scopus 로고
    • Frequent genetic alterations in flat urothelial hyperplasias and concomitant papillary bladder cancer as detected by CGH, LOH and FISH analyses
    • Obermann EQ Junker K, Stoehr R, Dietmaier W, Zaak D, Schubert J, et al. Frequent genetic alterations in flat urothelial hyperplasias and concomitant papillary bladder cancer as detected by CGH, LOH and FISH analyses. J Pathol 2003;199:50-7.
    • (2003) J Pathol , vol.199 , pp. 50-57
    • Obermann, E.Q.1    Junker, K.2    Stoehr, R.3    Dietmaier, W.4    Zaak, D.5    Schubert, J.6
  • 19
  • 20
    • 0033030354 scopus 로고    scopus 로고
    • Frequent genetic alterations in simple urothelial hyperplasias of the bladder in patients with papillary urothelial carcinoma
    • Hartmann A, Moser K, Kriegmair M, Hofstetter A, Hofstaedter F, Knuechel R. Frequent genetic alterations in simple urothelial hyperplasias of the bladder in patients with papillary urothelial carcinoma. Am J Pathol 1999;154:721-7.
    • (1999) Am J Pathol , vol.154 , pp. 721-727
    • Hartmann, A.1    Moser, K.2    Kriegmair, M.3    Hofstetter, A.4    Hofstaedter, F.5    Knuechel, R.6
  • 21
    • 0036468296 scopus 로고    scopus 로고
    • Occurrence of chromosome 9 and p53 alterations in multifocal dysplasia and carcinoma in situ of human urinary bladder
    • Hartmann A, Schlake G, Zaak D, Hungerhuber E, Hofstetter A, Hofstaedter F, et al. Occurrence of chromosome 9 and p53 alterations in multifocal dysplasia and carcinoma in situ of human urinary bladder. Cancer Res 2002;62:809-18.
    • (2002) Cancer Res , vol.62 , pp. 809-818
    • Hartmann, A.1    Schlake, G.2    Zaak, D.3    Hungerhuber, E.4    Hofstetter, A.5    Hofstaedter, F.6
  • 22
    • 1542540900 scopus 로고    scopus 로고
    • Numerical aberrations of chromosome 17 and the 9p21 locus are independent predictors of tumor recurrence in non-invasive transitional cell carcinoma of the urinary bladder
    • Kruger S, Mess F, Bohle A, Feller AC. Numerical aberrations of chromosome 17 and the 9p21 locus are independent predictors of tumor recurrence in non-invasive transitional cell carcinoma of the urinary bladder. Int J Oncol 2003;23:41-8.
    • (2003) Int J Oncol , vol.23 , pp. 41-48
    • Kruger, S.1    Mess, F.2    Bohle, A.3    Feller, A.C.4
  • 23
    • 2342591455 scopus 로고    scopus 로고
    • The discovery of receptor tyrosine kinases: Targets for cancer therapy
    • Gschwind A, Fischer OM, Ullrich A The discovery of receptor tyrosine kinases: Targets for cancer therapy. Nat Rev Cancer 2004;4:361-70.
    • (2004) Nat Rev Cancer , vol.4 , pp. 361-370
    • Gschwind, A.1    Fischer, O.M.2    Ullrich, A.3
  • 24
    • 10744222289 scopus 로고    scopus 로고
    • FGFS3 and TP53 gene mutations define two distinct pathways in urothelial cell carcinoma of the bladder
    • Bakkar AA, Wallerand H, Radvanyi F, Lahaye JB, Pissard S, Lecerf L, et al. FGFS3 and TP53 gene mutations define two distinct pathways in urothelial cell carcinoma of the bladder. Cancer Res 2003;63:8108-12.
    • (2003) Cancer Res , vol.63 , pp. 8108-8112
    • Bakkar, A.A.1    Wallerand, H.2    Radvanyi, F.3    Lahaye, J.B.4    Pissard, S.5    Lecerf, L.6
  • 26
    • 0034969685 scopus 로고    scopus 로고
    • Billerey C, Chopin D, Aubriot-Lorton MH, Ricol D, Gil Diez de Medina S, Van Rhijn B, et al. Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors. An J Pathol 2001;158:1955-9.
    • Billerey C, Chopin D, Aubriot-Lorton MH, Ricol D, Gil Diez de Medina S, Van Rhijn B, et al. Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors. An J Pathol 2001;158:1955-9.
  • 27
    • 23444440484 scopus 로고    scopus 로고
    • Jebar AH, Hurst CD, Tomlinson DC, Johnston C, Taylor CF, Knowles MA FGFR3 and ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma. Oncogene 2005;24:5218-25.
    • Jebar AH, Hurst CD, Tomlinson DC, Johnston C, Taylor CF, Knowles MA FGFR3 and ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma. Oncogene 2005;24:5218-25.
  • 28
    • 0141954162 scopus 로고    scopus 로고
    • The role of ras superfamily proteins in bladder cancer progression
    • Oxford G, Thcodorescu D. The role of ras superfamily proteins in bladder cancer progression. J Urol 2003;170:1987-93.
    • (2003) J Urol , vol.170 , pp. 1987-1993
    • Oxford, G.1    Thcodorescu, D.2
  • 29
    • 0035866380 scopus 로고    scopus 로고
    • The fibroblast growth factor receptor 3 (FGFR mutation is a strong indicator of superficial bladder cancer with low recurrence rate
    • van Rhijn BW, Lurkin I, Radvanyi F, Kirkels WJ, van der Kwast TH, Zwarthoff EC. The fibroblast growth factor receptor 3 (FGFR mutation is a strong indicator of superficial bladder cancer with low recurrence rate. Cancer Res 2001;61:1265-8.
    • (2001) Cancer Res , vol.61 , pp. 1265-1268
    • van Rhijn, B.W.1    Lurkin, I.2    Radvanyi, F.3    Kirkels, W.J.4    van der Kwast, T.H.5    Zwarthoff, E.C.6
  • 30
    • 1542405934 scopus 로고    scopus 로고
    • FGFR3 and P53 characterize alternative genetic pathways in the pathogenesis of urothelial cell carcinoma
    • van Rhijn BW, van der Kwast TH, Vis AN, Kirkels WJ, Boevé ER Jöbsis AC, et al. FGFR3 and P53 characterize alternative genetic pathways in the pathogenesis of urothelial cell carcinoma. Cancer Res 2004;64:1911-4.
    • (2004) Cancer Res , vol.64 , pp. 1911-1914
    • van Rhijn, B.W.1    van der Kwast, T.H.2    Vis, A.N.3    Kirkels, W.J.4    Boevé, E.R.5    Jöbsis, A.C.6
  • 31
    • 0038011950 scopus 로고    scopus 로고
    • Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MB-1 is superior to pathologic grade for the prediction of clinical outcome
    • van Rhijn BW Vis AN, van der Kwast TH, Kirkels WJ, Radvanyi F, Ooms EC, et al. Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MB-1 is superior to pathologic grade for the prediction of clinical outcome. J Clin Oncol 2003;21:1912-21.
    • (2003) J Clin Oncol , vol.21 , pp. 1912-1921
    • van Rhijn, B.W.1    Vis, A.N.2    van der Kwast, T.H.3    Kirkels, W.J.4    Radvanyi, F.5    Ooms, E.C.6
  • 32
    • 0035081241 scopus 로고    scopus 로고
    • Ornitz DM, Itoh N. Fibroblast growth factors. Genome Biol 2001;2:BEVIEWS3005.
    • Ornitz DM, Itoh N. Fibroblast growth factors. Genome Biol 2001;2:BEVIEWS3005.
  • 33
    • 0038011950 scopus 로고    scopus 로고
    • Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MB-1 is superior to pathologic grade for the prediction of clinical outcome
    • van Rhijn BW Vis AN, van der Kwast TH, Kirkels WJ, Radvanyi F, Ooms EC, et al. Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MB-1 is superior to pathologic grade for the prediction of clinical outcome. J Clin Oncol 2003;21:1912-21.
    • (2003) J Clin Oncol , vol.21 , pp. 1912-1921
    • van Rhijn, B.W.1    Vis, A.N.2    van der Kwast, T.H.3    Kirkels, W.J.4    Radvanyi, F.5    Ooms, E.C.6
  • 34
    • 27744515561 scopus 로고    scopus 로고
    • Role of activating fibroblast growth, factor receptor 3 mutations in the development of bladder tumors
    • Zieger K, Dyrskjot L, Wiuf C, Jensen JL, Andersen CL, Jensen KM, et al. Role of activating fibroblast growth, factor receptor 3 mutations in the development of bladder tumors. Clin Cancer Res 2005;11:7709-19.
    • (2005) Clin Cancer Res , vol.11 , pp. 7709-7719
    • Zieger, K.1    Dyrskjot, L.2    Wiuf, C.3    Jensen, J.L.4    Andersen, C.L.5    Jensen, K.M.6
  • 35
    • 23044479419 scopus 로고    scopus 로고
    • FGFR3 and Tp53 mutations in T1G3transitional bladder carcinomas: Independent distribution and lack of association with prognosis
    • Hernandez S, Lopez-Knowles E, ∐oreta J, Kogevinas M, Jarainillo R, Auorós A, et al. FGFR3 and Tp53 mutations in T1G3transitional bladder carcinomas: Independent distribution and lack of association with prognosis. Clin Cancer Res 2005;11:5444-50.
    • (2005) Clin Cancer Res , vol.11 , pp. 5444-5450
    • Hernandez, S.1    Lopez-Knowles, E.2    ∐oreta, J.3    Kogevinas, M.4    Jarainillo, R.5    Auorós, A.6
  • 36
    • 32944481619 scopus 로고    scopus 로고
    • Mhawech-Fauceglia P, Cheney RT, Fischer G, Beck A, Herrmann FR FGFR3 and p53 protein expressions in patients with pTa and pT1 urothelial bladder cancer. Eur J Surg Oncol 2006;32:231-7.
    • Mhawech-Fauceglia P, Cheney RT, Fischer G, Beck A, Herrmann FR FGFR3 and p53 protein expressions in patients with pTa and pT1 urothelial bladder cancer. Eur J Surg Oncol 2006;32:231-7.
  • 38
    • 0035848685 scopus 로고    scopus 로고
    • Role of ha-ras activation in superficial papillary pathway of urothelial tumor formation
    • Zhang ZT, Pak J, Huang HY, Shapiro E, Sun TT, Pellicer A, et al. Role of ha-ras activation in superficial papillary pathway of urothelial tumor formation. Oncogene 2001;20:1973-80.
    • (2001) Oncogene , vol.20 , pp. 1973-1980
    • Zhang, Z.T.1    Pak, J.2    Huang, H.Y.3    Shapiro, E.4    Sun, T.T.5    Pellicer, A.6
  • 39
    • 0028802758 scopus 로고
    • Comparison of bladder cancer outcome in men undergoing hematuria home screening versus those with standard clinical presentations
    • Messing EM, Young TB, Hunt VB, Gilchrist KW, Newton MA, Brain LL, et al. Comparison of bladder cancer outcome in men undergoing hematuria home screening versus those with standard clinical presentations. Urology 1995;45:387-97.
    • (1995) Urology , vol.45 , pp. 387-397
    • Messing, E.M.1    Young, T.B.2    Hunt, V.B.3    Gilchrist, K.W.4    Newton, M.A.5    Brain, L.L.6
  • 40
    • 11244344381 scopus 로고    scopus 로고
    • Sengupta S, Harris CC. p53: Traffic cop at the crossroads of DNArepair and recombination. Nat Rev Mol Cell Biol 2005;6:44-55.
    • Sengupta S, Harris CC. p53: Traffic cop at the crossroads of DNArepair and recombination. Nat Rev Mol Cell Biol 2005;6:44-55.
  • 41
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone LR White A, Sprouse J, Livanos E. Jacks T, Tlsty TD. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 1992;70:923-35.
    • (1992) Cell , vol.70 , pp. 923-935
    • Livingstone, L.R.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tlsty, T.D.6
  • 42
    • 0031693740 scopus 로고    scopus 로고
    • Molecular alterations in bladder cancer
    • Cordon-Cardo C. Molecular alterations in bladder cancer. Cancer Surv 1998;32:115-31.
    • (1998) Cancer Surv , vol.32 , pp. 115-131
    • Cordon-Cardo, C.1
  • 43
    • 0031717333 scopus 로고    scopus 로고
    • Molecular alterations in bladder cancer
    • Ortoft TF, Wolf H. Molecular alterations in bladder cancer. Urol Res 1998;26:223-33.
    • (1998) Urol Res , vol.26 , pp. 223-233
    • Ortoft, T.F.1    Wolf, H.2
  • 45
    • 0030885701 scopus 로고    scopus 로고
    • p53 expression compared with, other prognostic factors in OMS grade-I stage-ta transitional cell carcinoma of the bladder
    • Casetta G, Gontero P, Russo R, Pacchioni D, Tizzani A. p53 expression compared with, other prognostic factors in OMS grade-I stage-ta transitional cell carcinoma of the bladder. Eur Urol 1997;32:229-36.
    • (1997) Eur Urol , vol.32 , pp. 229-236
    • Casetta, G.1    Gontero, P.2    Russo, R.3    Pacchioni, D.4    Tizzani, A.5
  • 47
    • 0033839271 scopus 로고    scopus 로고
    • Evaluation of P53 protein overexpression, Ki67 proliferative activity and mitotic index as markers of tumour recurrence in superficial transitional cell carcinoma of the bladder
    • Gontero P, Casetta G, Zitella A, Ballario R, Pacchioni D, Magnani C, et al. Evaluation of P53 protein overexpression, Ki67 proliferative activity and mitotic index as markers of tumour recurrence in superficial transitional cell carcinoma of the bladder. Eur Urol. 2000;38:287-96.
    • (2000) Eur Urol , vol.38 , pp. 287-296
    • Gontero, P.1    Casetta, G.2    Zitella, A.3    Ballario, R.4    Pacchioni, D.5    Magnani, C.6
  • 48
    • 23044479419 scopus 로고    scopus 로고
    • FGFR3 and Tp53 mutations in T1G3 transitional bladder carcinomas: Independent distribution and lack of association with prognosis
    • Hernandez S, Lopez-Knowles E, ∐oreta J, Kogevinas M, Jarainillo R, Amorós A, et al. FGFR3 and Tp53 mutations in T1G3 transitional bladder carcinomas: Independent distribution and lack of association with prognosis, Clin Cancer Res 2005;11:5444-50.
    • (2005) Clin Cancer Res , vol.11 , pp. 5444-5450
    • Hernandez, S.1    Lopez-Knowles, E.2    ∐oreta, J.3    Kogevinas, M.4    Jarainillo, R.5    Amorós, A.6
  • 49
    • 0029768723 scopus 로고    scopus 로고
    • Overexpression of p53 protein in a high-risk population of patients with, superficial bladder cancer before and after bacillus calmette-guerin therapy: Correlation to clinical outcome
    • Lacombe L, Dalbagni G, Zhang ZF, Cordon-Cardo C, Fair WR, Herr HW, et al. Overexpression of p53 protein in a high-risk population of patients with, superficial bladder cancer before and after bacillus calmette-guerin therapy: Correlation to clinical outcome. J Clin Oncol 1996;14:2646-52.
    • (1996) J Clin Oncol , vol.14 , pp. 2646-2652
    • Lacombe, L.1    Dalbagni, G.2    Zhang, Z.F.3    Cordon-Cardo, C.4    Fair, W.R.5    Herr, H.W.6
  • 50
    • 15644377551 scopus 로고    scopus 로고
    • Biomarker study of primary nonmetastatic versus metastatic invasive bladder cancer: National cancer institute bladder tumor marker network
    • lianes P, Charytonowicz E, Cordon-Cardo C, Fradet Y, Grossman HB, Hemstreet GP, et al. Biomarker study of primary nonmetastatic versus metastatic invasive bladder cancer: National cancer institute bladder tumor marker network. Clin Cancer Res 1998;4:1267-71.
    • (1998) Clin Cancer Res , vol.4 , pp. 1267-1271
    • lianes, P.1    Charytonowicz, E.2    Cordon-Cardo, C.3    Fradet, Y.4    Grossman, H.B.5    Hemstreet, G.P.6
  • 51
    • 1842737599 scopus 로고    scopus 로고
    • Prognostic factors in stage T1 grade 3 bladder cancer survival: The role of G1-S modulators (p53, p21 Waf1, p27kip1, cyclin D1 and cyclin D and proliferation index ki67-MIB)
    • Lopez-Beltran A, Luque RJ, Alvarez-Kindelan J, Quintero A, Merlo F, Carrasco JC, et al. Prognostic factors in stage T1 grade 3 bladder cancer survival: The role of G1-S modulators (p53, p21 Waf1, p27kip1, cyclin D1 and cyclin D and proliferation index ki67-MIB). Eur Urol 2004;45:606-12.
    • (2004) Eur Urol , vol.45 , pp. 606-612
    • Lopez-Beltran, A.1    Luque, R.J.2    Alvarez-Kindelan, J.3    Quintero, A.4    Merlo, F.5    Carrasco, J.C.6
  • 52
    • 4344628144 scopus 로고    scopus 로고
    • Prognostic factors in survival of patients with stage ta and T1 bladder urothelial tumors: The role of Gl-S modulators (p53, p21Waf1, p27Kp1, cyclin D1 and cyclin D, proliferation index and clinicopathologic parameters
    • Lopez-Beltran A, Luque BJ, Alvarez-Kindelan J, Quintero A, Merlo F, Requena MJ, et al. Prognostic factors in survival of patients with stage ta and T1 bladder urothelial tumors: The role of Gl-S modulators (p53, p21Waf1, p27Kp1, cyclin D1 and cyclin D, proliferation index and clinicopathologic parameters. Am J Clin Pathol 2004;122:444-52.
    • (2004) Am J Clin Pathol , vol.122 , pp. 444-452
    • Lopez-Beltran, A.1    Luque, B.J.2    Alvarez-Kindelan, J.3    Quintero, A.4    Merlo, F.5    Requena, M.J.6
  • 54
    • 0342484451 scopus 로고    scopus 로고
    • p53 immunohistochemistry in bladder cancer, combined analysis: A way to go?
    • Schmitz-Drager BJ, Goebell PJ, Heydthausen M. p53 immunohistochemistry in bladder cancer, combined analysis: A way to go? Urol Oncol 2000;5:204-10.
    • (2000) Urol Oncol , vol.5 , pp. 204-210
    • Schmitz-Drager, B.J.1    Goebell, P.J.2    Heydthausen, M.3
  • 56
    • 1842457693 scopus 로고    scopus 로고
    • p53, p21, pRB and p.16 expression predict clinical outcome in cystectomy with bladder cancer
    • Shariat SF, Tokunaga H, Zhou J, Kim J, Ayala GE Benedict WF, et al. p53, p21, pRB and p.16 expression predict clinical outcome in cystectomy with bladder cancer. J Clin Oncol 2004;22:1014-24.
    • (2004) J Clin Oncol , vol.22 , pp. 1014-1024
    • Shariat, S.F.1    Tokunaga, H.2    Zhou, J.3    Kim, J.4    Ayala, G.E.5    Benedict, W.F.6
  • 57
    • 33846003867 scopus 로고    scopus 로고
    • Predictive value of cell cycle biomarkers in nonmuscle invasive bladder transitional cell carcinoma
    • Shariat SF, Ashfaq R, Sagalowsky AL Lotan Y. Predictive value of cell cycle biomarkers in nonmuscle invasive bladder transitional cell carcinoma. J Urol. 2007;177:481-7.
    • (2007) J Urol , vol.177 , pp. 481-487
    • Shariat, S.F.1    Ashfaq, R.2    Sagalowsky AL Lotan, Y.3
  • 58
    • 33748028804 scopus 로고    scopus 로고
    • Cell cycle control and beyond: Emerging roles for the retinoblastoma gene family
    • Genovese C, Trani D, Caputi M, Claudio PP. Cell cycle control and beyond: Emerging roles for the retinoblastoma gene family. Oncogene 2006;25:5201-9.
    • (2006) Oncogene , vol.25 , pp. 5201-5209
    • Genovese, C.1    Trani, D.2    Caputi, M.3    Claudio, P.P.4
  • 59
  • 60
    • 33749053635 scopus 로고    scopus 로고
    • Molecular biology of bladder cancer: Prognostic and clinical implications
    • Mtra AP, Lin H, Datar RH, Cote RJ. Molecular biology of bladder cancer: Prognostic and clinical implications. Clin Genitourin Cancer 2006;5:67-77.
    • (2006) Clin Genitourin Cancer , vol.5 , pp. 67-77
    • Mtra, A.P.1    Lin, H.2    Datar, R.H.3    Cote, R.J.4
  • 61
    • 1842509884 scopus 로고    scopus 로고
    • Combined effects of p53, p21 and pRb expression in the progression of bladder transitional cell carcinoma
    • Chatterjee SJ, Datar R, Youssefzadeh D, George B, Goebell PJ, Stein JP, et al. Combined effects of p53, p21 and pRb expression in the progression of bladder transitional cell carcinoma. J Clin Oncol 2004;22:1007-13.
    • (2004) J Clin Oncol , vol.22 , pp. 1007-1013
    • Chatterjee, S.J.1    Datar, R.2    Youssefzadeh, D.3    George, B.4    Goebell, P.J.5    Stein, J.P.6
  • 62
    • 0032521376 scopus 로고    scopus 로고
    • Elevated and absent pRb expression is associated with bladder cancer progression and has cooperative effects with p53
    • Cote RI, Dunn MD, Chatterjee SJ, Stein JP, Shi SR Tran QC, et al. Elevated and absent pRb expression is associated with bladder cancer progression and has cooperative effects with p53. Cancer Res 1998;58:1090-4.
    • (1998) Cancer Res , vol.58 , pp. 1090-1094
    • Cote, R.I.1    Dunn, M.D.2    Chatterjee, S.J.3    Stein, J.P.4    Shi, S.R.5    Tran, Q.C.6
  • 63
    • 0033565558 scopus 로고    scopus 로고
    • Urothelium-specific expression of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma
    • Zhang ZT, Pak J, Shapiro E, Sun TT, Wu XR. Urothelium-specific expression of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma. Cancer Res 1999;59:3512-7.
    • (1999) Cancer Res , vol.59 , pp. 3512-3517
    • Zhang, Z.T.1    Pak, J.2    Shapiro, E.3    Sun, T.T.4    Wu, X.R.5
  • 65
    • 0242440246 scopus 로고    scopus 로고
    • Preoperative plasma soluble E-cadherin predicts metastases to lymph nodes and prognosis in patients undergoing radical cystectomy
    • Matsumoto K, Shariat SF, Casella R, Wheeler TM, Slawin KM, Lerner SP. Preoperative plasma soluble E-cadherin predicts metastases to lymph nodes and prognosis in patients undergoing radical cystectomy. J Urol 2003;170:2248-52.
    • (2003) J Urol , vol.170 , pp. 2248-2252
    • Matsumoto, K.1    Shariat, S.F.2    Casella, R.3    Wheeler, T.M.4    Slawin, K.M.5    Lerner, S.P.6
  • 66
    • 0034089127 scopus 로고    scopus 로고
    • Low E-cadherin expression in bladder cancer at the transcriptional and protein level provides prognostic information
    • Popov Z, Gil-Diez de Medina S, Lefrere-Belda MA Hoznek A, Bastuji-Garin S, Abbou CC, et al. Low E-cadherin expression in bladder cancer at the transcriptional and protein level provides prognostic information. Br J Cancer 2000;83:209-14.
    • (2000) Br J Cancer , vol.83 , pp. 209-214
    • Popov, Z.1    Gil-Diez de Medina, S.2    Lefrere-Belda, M.A.3    Hoznek, A.4    Bastuji-Garin, S.5    Abbou, C.C.6
  • 67
    • 0035151885 scopus 로고    scopus 로고
    • E-cadherin expression predicts clinical outcome in carcinoma in situ of the urinary bladder
    • Shariat SF, Pahlavan S, Baseman AG, Brown SM Green AE, Wheeler TM, et al. E-cadherin expression predicts clinical outcome in carcinoma in situ of the urinary bladder. Urology 2001;57:60-5.
    • (2001) Urology , vol.57 , pp. 60-65
    • Shariat, S.F.1    Pahlavan, S.2    Baseman, A.G.3    Brown, S.M.4    Green, A.E.5    Wheeler, T.M.6
  • 68
    • 0026083903 scopus 로고
    • Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma
    • Weidner N, Semple JR Welch WR, Folkman J. Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 1991;324:1-8.
    • (1991) N Engl J Med , vol.324 , pp. 1-8
    • Weidner, N.1    Semple, J.R.2    Welch, W.R.3    Folkman, J.4
  • 69
  • 70
    • 0034827699 scopus 로고    scopus 로고
    • Serum levels of vascular endothelial growth tactor as a prognostic factor in bladder cancer
    • Bernardim S, Fauconnet S, Chabannes E, Henry PC, Adessi G, Bittard H. Serum levels of vascular endothelial growth tactor as a prognostic factor in bladder cancer. J Urol 2001;166:1275-9.
    • (2001) J Urol , vol.166 , pp. 1275-1279
    • Bernardim, S.1    Fauconnet, S.2    Chabannes, E.3    Henry, P.C.4    Adessi, G.5    Bittard, H.6
  • 72
    • 0037817325 scopus 로고    scopus 로고
    • Significant association of Rho/ROCKpathway with invasion and metastasis of bladder cancer
    • Kamai T, Tsujii T, Arai K, Takagi K, Asami H, Ito Y, et al. Significant association of Rho/ROCKpathway with invasion and metastasis of bladder cancer. Clin Cancer Res 2003;9:2632-41.
    • (2003) Clin Cancer Res , vol.9 , pp. 2632-2641
    • Kamai, T.1    Tsujii, T.2    Arai, K.3    Takagi, K.4    Asami, H.5    Ito, Y.6
  • 74
    • 2542606977 scopus 로고    scopus 로고
    • Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer
    • Theodorescu D, Sapinoso LM, Conaway MR, Oxford G, Hampton GM, Frierson HF Jr. Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer. Clin Cancer Res 2004;10:3800-6.
    • (2004) Clin Cancer Res , vol.10 , pp. 3800-3806
    • Theodorescu, D.1    Sapinoso, L.M.2    Conaway, M.R.3    Oxford, G.4    Hampton, G.M.5    Frierson Jr, H.F.6
  • 75
    • 33748470523 scopus 로고    scopus 로고
    • Postoperative nomogram predicting risk of recurrence after radical cystectomy for bladder cancer
    • International Bladder Cancer Nomogram Consortium
    • International Bladder Cancer Nomogram Consortium, Bochner BH, Kattan MW, Vora KC. Postoperative nomogram predicting risk of recurrence after radical cystectomy for bladder cancer. J Clin Oncol 2006;24:3967-72.
    • (2006) J Clin Oncol , vol.24 , pp. 3967-3972
    • Bochner, B.H.1    Kattan, M.W.2    Vora, K.C.3
  • 77
    • 0037435030 scopus 로고    scopus 로고
    • Mass spectrometry-based proteoinics
    • Aebersold R, Mann M. Mass spectrometry-based proteoinics. Nature 2003;422:198-207.
    • (2003) Nature , vol.422 , pp. 198-207
    • Aebersold, R.1    Mann, M.2
  • 78
    • 17444438042 scopus 로고    scopus 로고
    • Applications of array technology: Identification of molecular targets in bladder cancer
    • Sanchez-Carbayo M, Cordon-Cardo C. Applications of array technology: Identification of molecular targets in bladder cancer. Br J Cancer 2003;89:2172-7.
    • (2003) Br J Cancer , vol.89 , pp. 2172-2177
    • Sanchez-Carbayo, M.1    Cordon-Cardo, C.2
  • 80
    • 2942648713 scopus 로고    scopus 로고
    • The p53 pathway: Targets for the development of novel cancer therapeutics
    • Wang S, El-Deiry WS. The p53 pathway: Targets for the development of novel cancer therapeutics. Cancer Treat Res 2004;119:175-87.
    • (2004) Cancer Treat Res , vol.119 , pp. 175-187
    • Wang, S.1    El-Deiry, W.S.2
  • 81
    • 1842529509 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Cancer gene therapy using tumour suppressor genes
    • McNeish IA, Bell SJ, Lemoine NR Gene therapy progress and prospects: Cancer gene therapy using tumour suppressor genes. Gene Ther 2004;11:497-503.
    • (2004) Gene Ther , vol.11 , pp. 497-503
    • McNeish, I.A.1    Bell, S.J.2    Lemoine, N.R.3
  • 82
    • 33751232026 scopus 로고    scopus 로고
    • Molecular markers of prognosis and novel therapeutic strategies for urothelial cell carcinomas
    • Thomas CY, Theodorescu D. Molecular markers of prognosis and novel therapeutic strategies for urothelial cell carcinomas. World J Urol 2006;24:565-78.
    • (2006) World J Urol , vol.24 , pp. 565-578
    • Thomas, C.Y.1    Theodorescu, D.2
  • 83
    • 34247337239 scopus 로고    scopus 로고
    • Molecular pathways in invasive bladder cancer: New insights into mechanisms, progression and target identification
    • Mitra AR Datar BH, Cote SJ. Molecular pathways in invasive bladder cancer: New insights into mechanisms, progression and target identification. J Clin Oncol 2006;24:5552-64.
    • (2006) J Clin Oncol , vol.24 , pp. 5552-5564
    • Mitra, A.R.1    Datar, B.H.2    Cote, S.J.3
  • 85
    • 0037377269 scopus 로고    scopus 로고
    • The p53 tumor suppressor gene and nuclear protein: Basic science review and relevance in the management of bladder cancer
    • Smith ND, Rubenstein JN, Eggener SE, Kozloswki JM. The p53 tumor suppressor gene and nuclear protein: Basic science review and relevance in the management of bladder cancer. J Urol 2003;169:1219-28.
    • (2003) J Urol , vol.169 , pp. 1219-1228
    • Smith, N.D.1    Rubenstein, J.N.2    Eggener, S.E.3    Kozloswki, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.