Liver cirrhosis in HIV-infected patients: Prevalence, aetiology and clinical outcome

Journal of Viral Hepatitis

Volumn 15, Issue 3, 2008, Pages 165-172

  Castellares, C ^a   Barreiro, P ^a   Martin Carbonero L ^a   Labarga, P ^a   Vispo, M E ^a   Casado, R ^a   Galindo, L ^a   Garcia Gasco P ^a   Garcia Samaniego J ^a   Soriano, V ^a  

^a HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

Author keywords

Alcohol; Cirrhosis; HIV; Liver; Viral hepatitis

Indexed keywords

ADULT; ALCOHOL ABUSE; ARTICLE; ASCITES; BIOASSAY; BLEEDING; BRAIN DISEASE; CAUSAL ATTRIBUTION; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DEVICE; ESOPHAGUS VARICES; FEMALE; FOLLOW UP; HEPATITIS B; HEPATITIS C; HEPATITIS DELTA VIRUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN IMMUNODEFICIENCY VIRUS PREVALENCE; INTRAVENOUS DRUG ABUSE; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; MIXED INFECTION; OBSERVATIONAL STUDY; OUTPATIENT DEPARTMENT; PRIORITY JOURNAL; PROGNOSIS; RETROSPECTIVE STUDY; SPAIN; SPLENOMEGALY; VARICOSIS; VIREMIA; VIRUS HEPATITIS;

ADULT; ANTI-HIV AGENTS; CD4 LYMPHOCYTE COUNT; CROSS-SECTIONAL STUDIES; FEMALE; HEPACIVIRUS; HEPATITIS DELTA VIRUS; HEPATITIS, CHRONIC; HIV INFECTIONS; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; ORTHOHEPADNAVIRUS; PREVALENCE; RETROSPECTIVE STUDIES; SPAIN; VIREMIA;

EID: 38449120595     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2007.00903.x     Document Type: Article

References (45)

1. Martín-Carbonero L, Soriano V, Valencia E, Garcia-Samaniego J, Lopez M, Gonzalez-Lahoz J. Increasing impact of chronic viral hepatitis on hospital admissions and mortality among HIV-infected patients. AIDS Res Hum Retroviruses 2001 17 : 1467 1471.
2. Mocroft A, Soriano V, Rockstroh J et al. Is there evidence for an increase in the death rate from liver-related disease in patients with HIV? AIDS 2005 19 : 2117 2125.
3. Benhamou Y, Bochet M, Di Martino V et al. Liver fibrosis progression in HIV and hepatitis C virus coinfected patients. The Multivirc Group. Hepatology 1999 30 : 1054 1058.
4. Poynard T, Mathurin P, Lai C et al. A comparison of fibrosis progression in chronic liver diseases. J Hepatol 2003 38 : 257 265.
5. Puoti M, Bonacini M, Spinetti A et al. Liver fibrosis progression is related to CD4 cell depletion in patients coinfected with hepatitis C virus and HIV. J Infect Dis 2001 183 : 134 137.
6. Pineda J, Romero-Gómez M, Díaz-García F et al. HIV coinfection shortens the survival of patients with hepatitis C virus-related decompensated cirrhosis. Hepatology 2005 41 : 779 789.
7. Barreiro P, Martin-Carbonero L, Nuñez M et al. Predictors of liver fibrosis in HIV-infected patients with chronic hepatitis C virus infection: assessment using transient elastometry and the role of HCV genotype 3. Clin Infect Dis 2006 42 : 1032 1039.
8. Aranzabal L, Casado J, Moya J et al. Influence of liver fibrosis on highly active antiretroviral therapy-associated hepatotoxicity in patients with HIV and hepatitis C virus coinfection. Clin Infect Dis 2005 40 : 588 593.
9. Barreiro P, Rodríguez-Novoa S, Labarga P et al. Influence of liver fibrosis stage on plasma levels of antiretroviral drugs in HIV-infected patients with chronic hepatitis C. J Infect Dis 2007 195 : 973 979.
10. Soriano V, Barreiro P, Nuñez M. Management of chronic hepatitis B and C in HIV-coinfected patients. J Antimicrob Chemother 2006 57 : 815 818.
11. Afdhal N. Diagnosing fibrosis in hepatitis C: is the pendulum swinging from biopsy to blood tests? Hepatology 2003 37 : 972 974.
12. Castera L, Vergniol J, Foucher J et al. Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. Gastroenterology 2005 128 : 343 350.
13. Sterling R, Lissen E, Clumeck N et al. Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection. Hepatology 2006 43 : 1318 1325.
14. Ziol M, Handra-Luca A, Kettaneh A et al. Non-invasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C. Hepatology 2005 41 : 48 54.
15. De Ledinghen V, Douvin C, Kettaneh A et al. Diagnosis of hepatic fibrosis and cirrhosis by transient elastography in HIV/hepatitis C virus-coinfected patients. J Acquir Immune Defic Syndr 2006 41 : 175 179.
16. Reuben A. Alcohol and the liver. Curr Opin Gastroenterol 2006 22 : 263 271.
17. Sulkowski M, Mehta S, Montes de Oca R, Thomas D, Moore R. Estimated prevalence of significant liver disease among 4,052 HIV-infected adults with and without chronic hepatitis B and C [abstract 842]. XII Conference on Retroviruses and Opportunistic Infections. Denver, CO, USA. February 5-8, 2006. Alexandria, VA, USA Foundation for Retrovirology and Human Health.
18. Rockstroh J, Mocroft A, Soriano V et al. Influence of hepatitis C virus infection on HIV-1 disease progression and response to highly active antiretroviral therapy. J Infect Dis 2005 192 : 992 1002.
19. Kellerman S, Hanson D, McNaghten A, Fleming P. Prevalence of chronic hepatitis B and incidence of acute hepatitis B infection in HIV-infected subjects. J Infect Dis 2003 188 : 571 577.
20. Konopnicki D, Mocroft A, De Wit S et al. Hepatitis B and HIV: prevalence, AIDS progression, response to highly active antiretroviral therapy and increased mortality in the EuroSIDA cohort. AIDS 2005 19 : 593 601.
21. Nuñez M, Ramos B, Díaz-Pollán B et al. Virological outcome of chronic hepatitis B virus infection in HIV-coinfected patients receiving anti-HBV active antiretroviral therapy. AIDS Res Hum Retroviruses 2006 22 : 842 848.
22. Iloeje U, Yang H, Su J et al. Predicting cirrhosis risk based on the level of circulating hepatitis B viral load. Gastroenterology 2006 130 : 678 686.
23. Chen C, Yang H, Su J et al. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 2006 295 : 65 73.
24. Di Martino V, Rufat P, Boyer N et al. The influence of HIV coinfection on chronic hepatitis C in injection drug users: a long term retrospective cohort study. Hepatology 2001 34 : 1193 1199.
25. Delarocque-Astagneau E, Roudot-Thoraval F, Campese C, Desenclos J, The Hepatitis C Surveillance System Steering Committee. Past excessive alcohol consumption: a major determinant of severe liver disease among newly referred hepatitis C virus infected patients in hepatology reference centers, France 2001. Ann Epidemiol 2005 15 : 551 557.
26. Nuñez M, Soriano V. Hepatotoxicity of antiretrovirals: incidence, mechanisms and management. Drug Saf 2005 28 : 53 66.
27. Maida I, Nuñez M, Ríos M et al. Severe liver disease of unknown origin in HIV-infected patients. J Acquir Immune Defic Syndr 2006 42 : 177 182.
28. Mallet V, Blanchard P, Verkarre V et al. Nodular regenerative hyperplasia is a new cause of chronic liver disease in HIV-infected patients. AIDS 2007 21 : 187 192.
29. Foucher J, Chanteloup E, Vergniol J et al. Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study. Gut 2006 55 : 403 408.
30. Merchante N, Girón-González J, González-Serrano M et al. Survival and prognostic factors of HIV-infected patients with HCV-related end-stage liver disease. AIDS 2006 20 : 49 57.
31. Miro J, Laguno M, Moreno A, Rimola A. Management of end stage liver disease: what is the current role of orthotopic liver transplantation? J Hepatol 2006 44 : 140 145.
32. Bonacini M, Louie S, Bzowej N, Rock A. Survival of patients with HIV infection and viral hepatitis B or C. AIDS 2004 10 : 2039 2045.
33. Kramer J, Giordanbo T, Souchek J, Richardson P, Hwang L, El-Serag H. The effect of HIV coinfection on the risk of cirrhosis and hepatocellular carcinoma in US veterans with hepatitis C. Am J Gastroenterol 2005 100 : 56 63.
34. Qurishi N, Kreuzberg C, Luchters G et al. Effect of antiretroviral therapy on liver-related mortality in patients with HIV and hepatitis C virus coinfection. Lancet 2003 362 : 1708 1713.
35. Greub G, Ledergerber B, Battegay M et al. Clinical progression, survival, and immune recovery during antiretroviral therapy in patients with HIV-1 and hepatitis C virus coinfection: the Swiss HIV Cohort Study. Lancet 2000 356 : 1800 1805.
36. Mohsen A, Easterbrook P, Taylor C et al. Impact of HIV infection on the progression of liver fibrosis in hepatitis C virus infected patients. Gut 2003 52 : 1035 1040.
37. Martin-Carbonero L, Benhamou Y, Puoti M et al. Incidence and predictors of severe liver fibrosis in HIV-infected patients with chronic hepatitis C: a European collaborative study. Clin Infect Dis 2004 38 : 128 133.
38. Barreiro P, Labarga P, Martín-Carbonero L et al. Sustained virological response following HCV therapy is associated with non-progression of liver fibrosis in HCV/HIV-coinfected patients. Antiviral Ther 2006 11 : 869 877.
39. Lissen E, Clumeck N, Sola R et al. Histological response to pegIFNalpha-2a (40KD) plus ribavirin in HIV-hepatitis C virus co-infection. AIDS 2006 20 : 2175 2181.
40. Soriano V, Labarga P, Ruiz-Sancho A, Garcia-Samaniego J, Barreiro P. Regression of liver fibrosis in hepatitis C virus/HIV-co-infected patients after treatment with pegylated interferon plus ribavirin. AIDS 2006 20 : 2225 2227.
41. Thio C, Seaberg E, Skolasky R et al. HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS). Lancet 2002 360 : 1921 1926.
42. Tseng P, Lu S, Tung H, Wang J, Changchien C, Lee C. Determinants of early mortality and benefits of lamivudine therapy in patients with hepatitis B virus-related decompensated liver cirrhosis. J Viral Hepat 2005 12 : 386 392.
43. Zarski J, Bohn B, Bastie A et al. Characteristics of patients with dual infection by hepatitis B and C viruses. J Hepatol 1998 28 : 27 33.
44. Weltman M, Brotodihardjo A, Crewe E et al. Coinfection with hepatitis B and C, or B, C and delta viruses results in severe chronic liver disease and responds poorly to interferon-alpha treatment. J Viral Hepat 1995 2 : 39 45.
45. Chuang W, Dai C, Chang W et al. Viral interaction and response in chronic hepatitis B and C coinfected patient with interferon-alpha plus ribavirin combination therapy. Antiviral Ther 2005 10 : 125 133.