Exposure of preimplantation embryos to insulin alters expression of imprinted genes

Comparative Medicine

Volumn 57, Issue 5, 2007, Pages 482-486

  Shao, Wei Juan ^a,b   Tao, Ling Yun ^c   Xie, Jian Yun ^b   Gao, Cheng ^b,c   Hu, Jian Hua ^b   Zhao, Ru Qian ^a  

^a NANJING AGRICULTURAL UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF PLANNED PARENTHOOD RESEARCH   (China)

^c YANGZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; INSULIN; RNA H19; SOMATOMEDIN B; ANTIDIABETIC AGENT; IGF2 PROTEIN, MOUSE; MESSENGER RNA; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLASTOCYST; BODY WEIGHT; CONTROLLED STUDY; CPG ISLAND; EMBRYO DEVELOPMENT; FEMALE; FETUS; FETUS DEVELOPMENT; GENE EXPRESSION; GENE SEQUENCE; GENOME IMPRINTING; METHYLATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PREIMPLANTATION EMBRYO; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; CHEMISTRY; DNA METHYLATION; DNA SEQUENCE; DRUG EFFECT; EMBRYO TRANSFER; GENE EXPRESSION REGULATION; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; MALE; METABOLISM; MOLECULAR GENETICS; NIDATION;

ANIMALS; BASE SEQUENCE; BLASTOCYST; CPG ISLANDS; DNA METHYLATION; EMBRYO IMPLANTATION; EMBRYO TRANSFER; EMBRYONIC DEVELOPMENT; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOMIC IMPRINTING; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-LIKE GROWTH FACTOR II; MALE; MICE; MICE, INBRED ICR; MOLECULAR SEQUENCE DATA; RNA, MESSENGER; RNA, UNTRANSLATED; SEQUENCE ANALYSIS, DNA;

EID: 38449113151     PISSN: 15320820     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Arney KL. 2003. H19 and Igf2 - enhancing the confusion? Trends Genet 19:17-23.
2. Barnes D, Sato G. 1980. Methods for growth of cultured cells in serum-free medium. Anal Biochem 102:255-270.
3. Bartolomei MS, Zemel S, Tilghman SM. 1991. Parental imprinting of the mouse H19 gene. Nature 351:153-155.
4. Brandeis M, Kafri T, Ariel M, Chaillet JR, McCarrey J, Razin A, Cedar H. 1993. The ontogeny of allele-specific methylation associated with imprinted genes in the mouse. EMBO J 12:3669-3677.
5. DeChiara TM, Efstratiadis A, Robertson EJ. 1990. A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 345:78-80.
6. DeChiara TM, Robertson EJ, Efstratiadis A. 1991. Parental imprinting of the mouse insulin-like growth factor II gene. Cell 64:849-859.
7. Doherty AS, Mann MR, Tremblay KD, Bartolomei MS, Schultz RM. 2000. Differential effects of culture on imprinted H19 expression in the preimplantation mouse embryo. Biol Reprod 62:1526-1535.
8. Dunglison GF, Jane SD, McCaul TF, Chad JE, Fleming TP, Kaye PL. 1995. Stimulation of endocytosis in mouse blastocysts by insulin: a quantitative morphological analysis. J Reprod And Fertil 105:115-123.
9. Dunglison GF, Kaye PL. 1993. Insulin regulates protein metabolism in mouse blastocysts. Mol Reprod Dev 36:42-48.
10. Feil R. 2006. Environmental and nutritional effects on the epigenetic regulation of genes. Mutat Res 600:46-57.
11. Feil R, Walter J, Allen ND. 1994. Developmental control of allelic methylation in the imprinted mouse Igf1 and H19 genes. Development 120:2933-2943.
12. Gardner HG, Kaye PL. 1991. Insulin increases cell numbers and morphological development in mouse preimplantation embryos in vitro. Reprod Fertil Dev 3:79-91.
13. Gebert C, Wrenzycki C, Herrmann D, Groger D, Reinhardt R, Hajkova P, Lucas-Hahn A, Carnwath J, Lehrach H, Niemann H. 2006. The bovine IGF2 gene is differentially methylated in oocyte and sperm DNA. Genomics 88:222-229.
14. Harvey MB, Kaye PL. 1988. Insulin stimulates protein synthesis in compacted mouse embryos. Endocrinology 122:1182-1184.
15. Harvey MB, Kaye PL. 1990. Insulin increases the cell number of the inner cell mass and stimulates morphological development of mouse blastocysts in vitro. Develop 110:963-967.
16. Hsieh CL. 2000. Dynamics of DNA methylation pattern. Curr Opin Genet Dev 10:224-228.
17. Kaye PL, Pemble LB, Hobbs JG. 1986. Protein metabolism in preimplantation mouse embryos. Prog Clin Biol Res 217B:103-106.
18. Khosla S, Dean W, Brown D, Reik W, Feil R. 2001.Culture of preimplantation mouse embryos affects fetal development and the expression of imprinted genes. Biol Reprod 64:918-926.
19. Leighton PA, Saam JR, Ingram RS, Stewart CL, Tilghman SM. 1995. An enhancer deletion affects both H19 and Igf2 expression. Genes Dev 9:2079-2089.
20. Livak KJ, Schmittgen TD. 2001.Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 25: 402-408.
21. Mattson BA, Rosenblum IY, Smith RM, Heyner S. 1988. Autoradiographic evidence for insulin and insulin-like growth factor binding to early mouse embryo. Diabetes 37:585-589.
22. Nagy A, Gertsenstein M, Vintersten K, Behringer R. 2002. Manipulating the mouse embryo: a laboratory manual, 3rd ed. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press.
23. Rappolee DA,Wang A, Mark D, Werb Z. 1989. Novel method for studying mRNA phenotypes in single or small numbers of cells. J Cell Biochem 39:1-11.
24. Reik W, Murrell A. 2000. Genomic imprinting. Silence across the border. Nature 405:408-409.
25. Rosenblum IY, Mattson BA, Heyner S. 1986. Stage-specific insulin binding in mouse preimplantation embryos. Dev Biol 116:261-263.
26. Sasaki H, Ferguson-Smith AC, Shum AS, Barton SC, Surani MA. 1995. Temporal and spatial regulation of H19 imprinting in normal and uniparental mouse embryos. Develop 121:4195-4202.
27. Serman A, Vlahovic M, Serman L, Bulic-Jakus F. 2006. DNA methylation as a regulatory mechanism for gene expression in mammals. Coll Antropol 30:665-671.
28. Smith FM, Garfield AS, Ward A. 2006. Regulation of growth and metabolism by imprinted genes. Cytogenet Genome Res 113:279-291.
29. Sun FL, Dean W, Kelsey G, Allen ND, Reik W. 1997. Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome. Nature 389:809-815.
30. Thorvaldsen JL, Duran KL, Bartolomei MS. 1998. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev 12:3693-3702.
31. Tremblay KD, Duran KL, Bartolomei MS. 1997. A 5′ 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development. Mol Cell Biol 17:4322-4329.
32. Ungaro P, Casola S, Vernucci M, Pedone PV, Bruni CB, Riccio A. 1997. Relaxation of insulin-like growth factor 2 imprinting in rat cultured cells. Mol Cell Endocrinol 135:153-163.
33. Waterland RA, Dolinoy DC, Lin JR, Smith CA, Shi X, Tahiliani K. 2006. Maternal methyl supplements increase offspring DNA methylation at axin fused[J]. Genesis 44:401-406.
34. Waterland RA, Jirtle RL. 2003. Transposable elements; targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol 23:5293-5300.
35. Waterland RA, Lin JR, Smith CA, Jirtle RL. 2006. Postweaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus. Hum Mol Genet 15:705-716.
36. Weber M, Milligan L, Delalbre A, Antoine E, Brunel C, Cathala G, Forne T. 2001. Extensive tissue-specific variation of allelic methylation in the Igf2 gene during mouse fetal development: relation to expression and imprinting. Mech Dev 101:133-141.
37. Wu Q, Ohsako S, Ishimura R, Suzuki JS, Tohyama C. 2004. Exposure of mouse preimplantation embryos to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters the methylation status of imprinted genes H19 and Igf2. Biol Reprod 70:1790-1797.
38. Zhu B, Huang XH, Chen JD, Lu YC, Chen Y, Zhao JY. 2006. Methylation changes of H19 gene in sperms of X-irradiated mouse and maintenance in offspring. Biochem Biophys Res Commun 340:83-89.