Noninvasive measurement of three-dimensional morphology of adhered animal cells employing phase-shifting laser microscope

Journal of Biomedical Optics

Volumn 12, Issue 5, 2007, Pages

  Takagi, Mutsumi ^a   Kitabayashi, Takayuki ^a   Ito, Syunsuke ^a   Fujiwara, Masashi ^a   Tokuda, Akio ^b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b 1 13 4 Nakano   (Japan)

Author keywords

Laser microscope; Morphology; Noninvasive; Three dimensional

Indexed keywords

ATOMIC FORCE MICROSCOPY; BONE; LASER RADIATION; MORPHOLOGY; REFRACTIVE INDEX;

ADHERED ANIMAL CELLS; SHIFTING LASER MICROSCOPE;

ANIMAL CELL CULTURE;

ANIMALIA; CRICETULUS GRISEUS;

ANIMAL; ARTICLE; CELL ADHESION; CELL CULTURE; CELL SIZE; COMPUTER ASSISTED DIAGNOSIS; CONFOCAL MICROSCOPY; EQUIPMENT; EQUIPMENT DESIGN; HUMAN; INSTRUMENTATION; METHODOLOGY; PHASE CONTRAST MICROSCOPY; PHYSIOLOGY; REFRACTOMETRY; THREE DIMENSIONAL IMAGING;

ANIMALS; CELL ADHESION; CELL SIZE; CELLS, CULTURED; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MICROSCOPY, CONFOCAL; MICROSCOPY, PHASE-CONTRAST; REFRACTOMETRY;

EID: 38449104112     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2779350     Document Type: Article

References (7)

1. M. Takagi, H. Hayashi, and T. Yoshida, "The effect of osmolarity on metabolism and morphology in adhesion and suspension Chinese hamster ovary cells producing tissue plasminogen activator," Cytotechnology 32, 171-179 (2000). (Pubitemid 30387878)
2. J. Endo, J. Chen, D. Kobayashi, Y. Wada, and H. Fujita, "Transmission laser microscope using the phase-shifting technique and its application to measurement of optical waveguides," Appl. Opt. 41(7), 1308-1314 (2002). (Pubitemid 34636156)
3. C. Matsuda, M. Takagi, T. Hattori, S. Wakitani, and T. Yoshida, "Differentiation of human bone marrow mesenchymal stem cells to chondrocytes for construction of three-dimensional cartilage tissue," Cytotechnology 47, 11-17 (2005). (Pubitemid 41784661)
4. M. Takagi, T. Nakamura, C. Matsuda, T. Hattori, S. Wakitani, and T. Yoshida, "In vitro proliferation of human bone marrow mesenchymal stem cells employing donor serum and basic fibroblast growth factor," Cytotechnology 43(1-3), 89-96 (2003). (Pubitemid 41184369)
5. H. J. Butt, E. K. Wolff, S. A. Gould, N. B. Dixon, C. M. Peterson, and P. K. Hansma, "Imaging cells with the atomic force microscope," J. Struct. Biol. 105, 54-61 (1990).
6. J. Sonke and A. W. Edith, "The physical basis of transparency in biological tissue: Ultrastructure and minimization of light scattering," J. Theor. Biol. 199, 181-198 (1999).
7. A. M. Richard, "Light scattering from biological cells: dependence of backscatter radiation on membrane thickness and refractive index," Appl. Opt. 18(5), 585-588 (1979).