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Volumn , Issue 72, 2007, Pages 159-163

CYP 2E1 mutant mice are resistant to DDC-induced enhancement of MPTP toxicity

Author keywords

CYP 2E1; DDC; MPTP; neurodegeneration; neurotoxicity; Parkinson's disease

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CYTOCHROME P450 2E1; DIETHYLDITHIOCARBAMIC ACID; DOPAMINE; NEUROTOXIN; TYROSINE 3 MONOOXYGENASE;

EID: 38449083742     PISSN: 03036995     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-211-73574-9_20     Document Type: Article
Times cited : (4)

References (24)
  • 1
    • 0001496694 scopus 로고
    • A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine
    • Burns RS, Chiueh CC, Markey SP, Ebert MH, Jacobowitz DM, Kopin IJ (1983) A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine. Proc Natl Acad Sci USA 80(14):45464550
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , Issue.14 , pp. 45464550
    • Burns, R.S.1    Chiueh, C.C.2    Markey, S.P.3    Ebert, M.H.4    Jacobowitz, D.M.5    Kopin, I.J.6
  • 2
    • 0021276089 scopus 로고
    • Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase
    • Chiba K, Trevor A, Castagnoli NJ (1984) Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase. Biochem Biophys Res Commun 120(2):574578
    • (1984) Biochem. Biophys. Res. Commun. , vol.120 , Issue.2 , pp. 574578
    • Chiba, K.1    Trevor, A.2    Castagnoli, N.J.3
  • 3
    • 0038650243 scopus 로고    scopus 로고
    • Molecular and cellular events regulating dopamine neuron survival
    • Chiara GD ed, Dopamine in the CNS II, Springer, Berlin Heidelberg New York Tokyo
    • Corsini GU, Maggio R, Vaglini F (2002) Molecular and cellular events regulating dopamine neuron survival. In: Chiara GD (ed) Handbook of experimental pharmacology. Dopamine in the CNS II, vol 154. Springer, Berlin Heidelberg New York Tokyo, pp 321-386
    • (2002) Handbook of Experimental Pharmacology , vol.154 , pp. 321-386
    • Corsini, G.U.1    Maggio, R.2    Vaglini, F.3
  • 4
    • 0022349344 scopus 로고
    • 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by pretreatment with diethyldithiocarbamate
    • Corsini GU, Pintus S, Chiueh CC, Weiss JF, Kopin IJ (1985) 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by pretreatment with diethyldithiocarbamate. Eur J Pharmacol 119 (1-2): 127-128
    • (1985) Eur. J. Pharmacol. , vol.119 , Issue.1-2 , pp. 127-128
    • Corsini, G.U.1    Pintus, S.2    Chiueh, C.C.3    Weiss, J.F.4    Kopin, I.J.5
  • 5
    • 0029845140 scopus 로고    scopus 로고
    • Animal models of Parkinson's disease: An empirical comparison with the phenomenology of the disease in man
    • Gerlach M, Riederer P (1996) Animal models of Parkinson's disease: an empirical comparison with the phenomenology of the disease in man. J Neural Transm 103 (8-9): 987-1041
    • (1996) J. Neural. Transm. , vol.103 , Issue.8-9 , pp. 987-1041
    • Gerlach, M.1    Riederer, P.2
  • 6
    • 0024381035 scopus 로고
    • Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) in the mouse
    • Heikkila RE, Sieber BA, Manzino L, Sonsalla PK (1989) Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) in the mouse. Mol Chem Neuropathol 10(3):171183
    • (1989) Mol. Chem. Neuropathol. , vol.10 , Issue.3 , pp. 171183
    • Heikkila, R.E.1    Sieber, B.A.2    Manzino, L.3    Sonsalla, P.K.4
  • 7
    • 0026342172 scopus 로고
    • Prolonged alterations in canine striatal dopamine metabolism following subtoxic doses of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) and 40-amino-MPTP are linked to the persistence of pyridinium metabolites
    • Johannessen JN, Sobotka TJ, Weise VK, Markey SP (1991) Prolonged alterations in canine striatal dopamine metabolism following subtoxic doses of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) and 40-amino-MPTP are linked to the persistence of pyridinium metabolites. J Neurochem 57(3):981990
    • (1991) J. Neurochem. , vol.57 , Issue.3 , pp. 981990
    • Johannessen, J.N.1    Sobotka, T.J.2    Weise, V.K.3    Markey, S.P.4
  • 8
    • 0002946770 scopus 로고
    • Mechanisms of 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine induced destruction of dopaminergic neurons
    • Herken H, Hucho F eds, Springer, Berlin Heidelberg New York Tokyo
    • Kopin IJ (1992) Mechanisms of 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine induced destruction of dopaminergic neurons. In: Herken H, Hucho F (eds) Handbook of experimental pharmacology, vol 102. Springer, Berlin Heidelberg New York Tokyo, pp 333-356
    • (1992) Handbook of Experimental Pharmacology , vol.102 , pp. 333-356
    • Kopin, I.J.1
  • 10
    • 0025125825 scopus 로고
    • Mechanism of ethanol induced hepatic injury
    • Lieber CS (1990) Mechanism of ethanol induced hepatic injury. Pharmacol Ther 46(1):141
    • (1990) Pharmacol. Ther. , vol.46 , Issue.1 , pp. 141
    • Lieber, C.S.1
  • 11
    • 0030935567 scopus 로고    scopus 로고
    • Cytochrome P-4502E1: Its physiological and pathological role
    • Lieber CS (1997) Cytochrome P-4502E1: its physiological and pathological role. Physiol Rev 77(2):517544
    • (1997) Physiol. Rev. , vol.77 , Issue.2 , pp. 517544
    • Lieber, C.S.1
  • 12
    • 0021137683 scopus 로고
    • Intraneuronal generation of a pyridinium metabolite may cause druginduced parkinsonism
    • Markey SP, Johannessen JN, Chiueh CC, Burns RS, Herkenham MA (1984) Intraneuronal generation of a pyridinium metabolite may cause druginduced parkinsonism. Nature 311(5985):464467
    • (1984) Nature , vol.311 , Issue.5985 , pp. 464467
    • Markey, S.P.1    Johannessen, J.N.2    Chiueh, C.C.3    Burns, R.S.4    Herkenham, M.A.5
  • 13
    • 0036874345 scopus 로고    scopus 로고
    • Drug-metabolizing cytochrome P450s in the brain
    • Miksys SL, Tyndale RF (2002) Drug-metabolizing cytochrome P450s in the brain. J Psychiat Neurosci 27(6):406415
    • (2002) J. Psychiat Neurosci. , vol.27 , Issue.6 , pp. 406415
    • Miksys, S.L.1    Tyndale, R.F.2
  • 14
    • 0021810979 scopus 로고
    • Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1, 2, 5, 6-tetrahydropyridine
    • Nicklas WJ, Vyas I, Heikkila RE (1985) Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1, 2, 5, 6-tetrahydropyridine. Life Sci 36(26):25032508
    • (1985) Life Sci. , vol.36 , Issue.26 , pp. 25032508
    • Nicklas, W.J.1    Vyas, I.2    Heikkila, R.E.3
  • 15
    • 0035877348 scopus 로고    scopus 로고
    • Inhibition of cytochrome P450 2E1 induces an increase in extracellular dopamine in rat substantia nigra: A new metabolic pathway?
    • Nissbrandt H, Bergquist F, Jonason J, Engberg G (2001) Inhibition of cytochrome P450 2E1 induces an increase in extracellular dopamine in rat substantia nigra: a new metabolic pathway? Synapse 40(4):294301
    • (2001) Synapse , vol.40 , Issue.4 , pp. 294301
    • Nissbrandt, H.1    Bergquist, F.2    Jonason, J.3    Engberg, G.4
  • 16
    • 0000106986 scopus 로고    scopus 로고
    • Biotransformation of xenobiotics
    • Klaassen CD ed, 5th edn. McGraw-Hill Education ISE Editions, New York
    • Parkinson A (1996) Biotransformation of xenobiotics. In: Klaassen CD (ed) Casarett and Doull's toxicology: the basic science of poisons, 5th edn. McGraw-Hill Education (ISE Editions), New York, pp 113-186
    • (1996) Casarett and Doull's Toxicology: The Basic Science of Poisons , pp. 113-186
    • Parkinson, A.1
  • 17
    • 0023001744 scopus 로고
    • Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine, by mitochondria
    • Ramsay RR, Singer TP (1986) Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine, by mitochondria. J Biol Chem 261(17):75857587
    • (1986) J. Biol. Chem. , vol.261 , Issue.17 , pp. 75857587
    • Ramsay, R.R.1    Singer, T.P.2
  • 18
    • 0022477535 scopus 로고
    • Fate of nigrostriatal neurons in young mature mice given 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine: A neurochemical and morphological reassessment
    • Ricaurte GA, Langston JW, Delanney LE, Irwin I, Peroutka SJ, Forno LS (1986) Fate of nigrostriatal neurons in young mature mice given 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine: a neurochemical and morphological reassessment. Brain Res 376(1):117124
    • (1986) Brain Res. , vol.376 , Issue.1 , pp. 117124
    • Ricaurte, G.A.1    Langston, J.W.2    Delanney, L.E.3    Irwin, I.4    Peroutka, S.J.5    Forno, L.S.6
  • 19
    • 0022496617 scopus 로고
    • Neurotoxic effects of N-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) in the cat. Tyrosine hydroxylase immunohistochemistry
    • Schneider JS, Markham CH (1986) Neurotoxic effects of N-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) in the cat. Tyrosine hydroxylase immunohistochemistry. Brain Res 373 (1-2): 258-267
    • (1986) Brain Res. , vol.373 , Issue.1-2 , pp. 258-267
    • Schneider, J.S.1    Markham, C.H.2
  • 20
    • 0000298292 scopus 로고
    • MPTP animal models of Parkinson's disease
    • Koller WC ed, Marcel Dekker, New York
    • Sonsalla PK, Nicklas WJ (1992) MPTP animal models of Parkinson's disease. In: Koller WC (ed) Handbook of Parkinson's disease. Marcel Dekker, New York, pp 319-340
    • (1992) Handbook of Parkinson's Disease , pp. 319-340
    • Sonsalla, P.K.1    Nicklas, W.J.2
  • 21
    • 0030916950 scopus 로고    scopus 로고
    • Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1, 3-dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat
    • Stott I, Murthy A, Robinson A, Thomas NW, Fry JR (1997) Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1, 3-dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat. Hum Exp Toxicol 16(5):262266
    • (1997) Hum. Exp. Toxicol. , vol.16 , Issue.5 , pp. 262266
    • Stott, I.1    Murthy, A.2    Robinson, A.3    Thomas, N.W.4    Fry, J.R.5
  • 22
    • 5444243967 scopus 로고    scopus 로고
    • Involvement of cytochrome P450 2E1 in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced mouse model of Parkinson's disease
    • Vaglini F, Pardini C, Viaggi C, Bartoli C, Dinucci D, Corsini GU (2004) Involvement of cytochrome P450 2E1 in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced mouse model of Parkinson's disease. J Neurochem 91(2):285298
    • (2004) J. Neurochem. , vol.91 , Issue.2 , pp. 285298
    • Vaglini, F.1    Pardini, C.2    Viaggi, C.3    Bartoli, C.4    Dinucci, D.5    Corsini, G.U.6
  • 23
    • 84983625674 scopus 로고
    • Cytochrome P450 enzymes in the brain
    • De Kloet RE, Sutanto W eds, Neurobiology of steroids, Academic Press, New York
    • Warner M, Wyss A, Yoshida S, Gustafsson JA (1994) Cytochrome P450 enzymes in the brain. In: De Kloet RE, Sutanto W (eds) Methods in neurosciences. Neurobiology of steroids, vol 22. Academic Press, New York, pp 51-66
    • (1994) Methods in Neurosciences , vol.22 , pp. 51-66
    • Warner, M.1    Wyss, A.2    Yoshida, S.3    Gustafsson, J.A.4
  • 24
    • 0026752794 scopus 로고
    • MK-801 prevents 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced parkinsonism in primates
    • Zuddas A, Oberto G, Vaglini F, Fascetti F, Fornai F, Corsini GU (1992) MK-801 prevents 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced parkinsonism in primates. J Neurochem 59(2):733739
    • (1992) J. Neurochem. , vol.59 , Issue.2 , pp. 733739
    • Zuddas, A.1    Oberto, G.2    Vaglini, F.3    Fascetti, F.4    Fornai, F.5    Corsini, G.U.6


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