Molecular basis for the regenerative properties of a secretion of the mollusk Cryptomphalus aspersa

Skin Pharmacology and Physiology

Volumn 21, Issue 1, 2008, Pages 15-22

  Brieva, A ^a   Philips, N ^c   Tejedor, R ^b   Guerrero, A ^a   Pivel, J P ^a   Alonso Lebrero, J L ^a   Gonzalez, S ^d  

^a IFC SA   (Spain)

^b HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^c FAIRLEIGH DICKINSON UNIVERSITY   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

C. aspersa, cellular and molecular effects; Cryptomphalus aspersa; Extracellular matrix assembly; Mollusk; SCA, regenerative properties; Skin aging

Indexed keywords

ACTIN; ANTIOXIDANT; GLUTATHIONE TRANSFERASE; METALLOPROTEINASE; NATURAL PRODUCT; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; CRYPTOMPHALUS ASPERSA; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLLUSC; NONHUMAN; PRIORITY JOURNAL; SKIN FIBROBLAST; WOUND HEALING;

ANIMALS; ANTIOXIDANTS; CELL PROLIFERATION; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; CYTOSKELETON; DOWN-REGULATION; FIBROBLASTS; HUMANS; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 2; REGENERATION; SNAILS;

EID: 38349191973     PISSN: 16605527     EISSN: None     Source Type: Journal    
DOI: 10.1159/000109084     Document Type: Article

References (25)

1. Watson RE, Griffiths CE: Pathogenic aspects of cutaneous photoaging. J Cosmet Dermatol 2005;4:230-236.
2. Kang S, Fisher GJ, Voorhees JJ: Photoaging: pathogenesis, prevention, and treatment. Clin Geriatr Med 2001;17:643-659, v-vi.
3. Yaar M, Eller MS, Gilchrest BA: Fifty years of skin aging. J Investig Dermatol Symp Proc 2002;7:51-58.
4. Yaar M, Eller MS: Mechanisms of aging. Arch Dermatol 2002;138:1429-1432.
5. Auf dem Keller U, Kumin A, Braun S, Werner S: Reactive oxygen species and their detoxification in healing skin wounds. J Invest Dermatol 2006;126(suppl):106-111.
6. Ashcroft GS, Horan MA, Ferguson MW: The effects of ageing on cutaneous wound healing in mammals. J Anat 1995;187:1-26.
7. Ledo E, de las Heras ME, Ledo A: Treatment for acute radiodermatitis with Cryptomphalus aspersa secretion. Radioprotección 1999;23.
8. Griendling KK, FitzGerald GA: Oxidative stress and cardiovascular injury. I. Basic mechanisms and in vivo monitoring of ROS. Circulation 2003;108:1912-1916.
9. Hayes JD, Flanagan JU, Jowsey IR: Glutathione transferases. Annu Rev Pharmacol Toxicol 2005;45:51-88.
10. Mitsuhashi T, Shimazaki M, Chanoki Y, Kuwahara H, Sakai T, Masuda H: Experimental pulmonary fibrosis induced by trisodium citrate and acid-citrate-dextrose. Exp Mol Pathol 1985;42:261-270.
11. Juranek I, Bezek S: Controversy of free radical hypothesis: reactive oxygen species - Cause or consequence of tissue injury? Gen Physiol Biophys 2005;24:263-278.
12. Grieve DJ, Byrne JA, Cave AC, Shah AM: Role of oxidative stress in cardiac remodelling after myocardial infarction. Heart Lung Circ 2004;13:132-138.
13. Katoh Y, Takayama S: Characterization of the growth responses of hamster fibroblasts and chondrogenic cells to fibroblast growth factor. Exp Cell Res 1984;150:131-140.
14. Seno M, Sasada R, Iwane M, Sudo K, Kurokawa T, Ito K, Igarashi K: Stabilizing basic fibroblast growth factor using protein engineering. Biochem Biophys Res Commun 1988;151:701-708.
15. Uhlrich S, Lagente O, Lenfant M, Courtois Y: Effect of heparin on the stimulation of non-vascular cells by human acidic and basic FGF. Biochem Biophys Res Commun 1986;137:1205-1213.
16. Prestrelski SJ, Fox GM, Arakawa T: Binding of heparin to basic fibroblast growth factor induces a conformational change. Arch Biochem Biophys 1992;293:314-319.
17. Tang CH, Yang RS, Huang TH, Liu SH, Fu WM: Enhancement of fibronectin fibrillogenesis and bone formation by basic fibroblast growth factor via protein kinase C-dependent pathway in rat osteoblasts. Mol Pharmacol 2004;66:440-449.
18. Tzima E, del Pozo MA, Shattil SJ, Chien S, Schwartz MA: Activation of integrins in endothelial cells by fluid shear stress mediates rho-dependent cytoskeletal alignment. EMBO J 2001;20:4639-4647.
19. Xue M, Le NT, Jackson CJ: Targeting matrix metalloproteases to improve cutaneous wound healing. Expert Opin Ther Targets 2006;10:143-155.
20. Ravanti L, Kahari VM: Matrix metalloproteinases in wound repair. Int J Mol Med 2000;6:391-407.
21. Kennedy SH, Rouda S, Qin H, Aho S, Selber J, Tan EM: Basic FGF regulates interstitial collagenase gene expression in human smooth muscle cells. J Cell Biochem 1997;65:32-41.
22. Kenagy RD, Hart CE, Stetler-Stevenson WG, Clowes AW: Primate smooth muscle cell migration from aortic explants is mediated by endogenous platelet-derived growth factor and basic fibroblast growth factor acting through matrix metalloproteinases 2 and 9. Circulation 1997;96:3555-3560.
23. Hoshi H, Konno S, Kikuchi M, Sendai Y, Satoh T: Fibroblast growth factor stimulates the gene expression and production of tissue inhibitor of metalloproteinase-1 in bovine granulosa cells. In Vitro Cell Dev Biol Anim 1995;31:559-563.
24. Varghese S, Ramsby ML, Jeffrey JJ, Canalis E: Basic fibroblast growth factor stimulates expression of interstitial collagenase and inhibitors of metalloproteinases in rat bone cells. Endocrinology 1995;136:2156-2162.
25. Chua CC, Chua BH, Zhao ZY, Krebs C, Diglio C, Perrin E: Effect of growth factors on collagen metabolism in cultured human heart fibroblasts. Connect Tissue Res 1991;26:271-281.