Gene expression in the rectus abdominus muscle of patients with and without pelvic organ prolapse

American Journal of Obstetrics and Gynecology

Volumn 198, Issue 2, 2008, Pages 220.e1-220.e7

  Hundley, Andrew F ^a   Yuan, Lingwen ^b   Visco, Anthony G ^c  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

actin; myosin; pelvic organ prolapse; real time reverse transcriptase polymerase chain reaction; rectus muscle

Indexed keywords

ACTIN; MESSENGER RNA; MYOSIN;

ADULT; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA MICROARRAY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PELVIC ORGAN PROLAPSE; PELVIS FLOOR; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RECTUS ABDOMINIS MUSCLE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; STATISTICAL SIGNIFICANCE;

EID: 38349183988     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2007.08.047     Document Type: Article

References (38)

1. Nichols D.H., and Randall C.L. Types of prolapse. In: Nichols D.H., and Randall C.L. (Eds). Vaginal surgery (1996), Lippincott Williams & Wilkins, Philadelphia
2. Olsen A.L., Smith V.J., Bergstrom J.O., Colling J.C., and Clark A.L. Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence. Obstet Gynecol 89 (1997) 501-506
3. Samuelsson E.C., Arne Victor F.T., Tibblin G., and Svardsudd K.F. Signs of genital prolapse in a Swedish population of women 20 to 59 years of age and possible related factors. Am J Obstet Gynecol 180 (1999) 299-305
4. Versi E., Harvey M.A., Cardozo L., Brincat M., and Studd J.W. Urogenital prolapse and atrophy at menopause: a prevalence study. Int Urogynecol J Pelvic Floor Dysfunct 12 (2001) 107-110
5. Boyles S.H., Weber A.M., and Meyn L. Procedures for pelvic organ prolapse in the United States, 1979-1997. Am J Obstet Gynecol 188 (2003) 108-115
6. Smith A.R., Hosker G.L., and Warrell D.W. The role of partial denervation of the pelvic floor in the aetiology of genitourinary prolapse and stress incontinence of urine. A neurophysiological study. Br J Obstet Gynaecol 96 (1989) 24-28
7. Allen R.E., Hosker G.L., Smith A.R., and Warrell D.W. Pelvic floor damage and childbirth: a neurophysiological study. Br J Obstet Gynaecol 97 (1990) 770-779
8. Mant J., Painter R., and Vessey M. Epidemiology of genital prolapse: observations from the Oxford Family Planning Association Study. Br J Obstet Gynaecol 104 (1997) 579-585
9. Swift S.E. The distribution of pelvic organ support in a population of female subjects seen for routine gynecologic health care. Am J Obstet Gynecol 183 (2000) 277-285
10. Dietz H.P., and Bennett M.J. The effect of childbirth on pelvic organ mobility. Obstet Gynecol 102 (2003) 223-228
11. Harris R.L., Cundiff G.W., Coates K.W., and Bump R.C. Urinary incontinence and pelvic organ prolapse in nulliparous women. Obstet Gynecol 92 (1998) 951-954
12. Rinne K.M., and Kirkinen P.P. What predisposes young women to genital prolapse?. Eur J Obstet Gynecol Reprod Biol 84 (1999) 23-25
13. McIntosh L.J., Stanitski D.F., Mallett V.T., Frahm J.D., Richardson D.A., and Evans M.I. Ehlers-Danlos syndrome: relationship between joint hypermobility, urinary incontinence, and pelvic floor prolapse. Gynecol Obstet Invest 41 (1996) 135-139
14. Al-Rawi Z.S., and Al-Rawi Z.T. Joint hypermobility in women with genital prolapse. Lancet 1 (1982) 1439-1441
15. Norton P.A., Baker J.E., Sharp H.C., and Warenski J.C. Genitourinary prolapse and joint hypermobility in women. Obstet Gynecol 85 (1995) 225-228
16. Sayer T.R., Dixon J.S., Hosker G.L., and Warrell D.W. A study of paraurethral connective tissue in women with stress incontinence of urine. Neurol Urodyn 9 (1990) 319-320
17. Visco A.G., and Yuan L. Differential gene expression in pubococcygeus muscle from patients with pelvic organ prolapse. Am J Obstet Gynecol 189 (2003) 102-112
18. Hundley A.F., Yuan L., and Visco A.G. Skeletal muscle heavy-chain polypeptide 3 and myosin binding protein H in the pubococcygeus muscle in patients with and without pelvic organ prolapse. Am J Obstet Gynecol 194 (2006) 1404-1410
19. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25 (2001) 402-408
20. Schrijver I., Zehnder J.L., and Cherry A.M. Cytogenetic and molecular genetic diagnostic tools. In: Rose B.D. (Ed). UpToDate. Wellesley, MA (2003)
21. Higuchi R., Fockler C., Dollinger G., and Watson R. Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Biotechnology (N Y) 11 (1993) 1026-1030
22. Heid C.A., Stevens J., Livak K.J., and Williams P.M. Real time quantitative PCR. Genome Res 6 (1996) 986-994
23. Winer J., Jung C.K., Shackel I., and Williams P.M. Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem 270 (1999) 41-49
24. Schmittgen T.D., Zakrajsek B.A., Mills A.G., Gorn V., Singer M.J., and Reed M.W. Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods. Anal Biochem 285 (2000) 194-204
25. Bump R.C., Mattiasson A., Bo K., et al. The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. Am J Obstet Gynecol 175 (1996) 10-17
26. Boreham M.K., Wai C.Y., Miller R.T., Schaffer J.I., and Word R.A. Morphometric analysis of smooth muscle in the anterior vaginal wall of women with pelvic organ prolapse. Am J Obstet Gynecol 187 (2002) 56-63
27. Boreham M.K., Wai C.Y., Miller R.T., Schaffer J.I., and Word R.A. Morphometric properties of the posterior vaginal wall in women with pelvic organ prolapse. Am J Obstet Gynecol 187 (2002) 1501-1508 discussion 1508-9
28. Norton P.A., Boyd C., and Deak S. Abnormal collagen ratios in women with genitourinary prolapse. Neurourol Urodyn 11 (1992) 2-4
29. Weidner A.C., Barber M.D., Visco A.G., Bump R.C., and Sanders D.B. Pelvic muscle electromyography of levator ani and external anal sphincter in nulliparous women and women with pelvic floor dysfunction. Am J Obstet Gynecol 183 (2000) 1390-1399 discussion 1399-401
30. Barnick C.G., and Cardozo L.D. Denervation and re-innervation of the urethral sphincter in the aetiology of genuine stress incontinence: an electromyographic study. Br J Obstet Gynaecol 100 (1993) 750-753
31. Boreham M.K., Miller R.T., Schaffer J.I., and Word R.A. Smooth muscle myosin heavy chain and caldesmon expression in the anterior vaginal wall of women with and without pelvic organ prolapse. Am J Obstet Gynecol 185 (2001) 944-952
32. Bukovsky A., Copas P., Caudle M.R., et al. Abnormal expression of p27kip1 protein in levator ani muscle of aging women with pelvic floor disorders-a relationship to the cellular differentiation and degeneration. BMC Clin Pathol 1 (2001) 4
33. Alberts B. Molecular biology of the cell (2002), Garland Science, New York
34. Lionikas A., Li M., and Larsson L. Human skeletal muscle myosin function at physiological and non-physiological temperatures. Acta Physiol (Oxf) 186 (2006) 151-158
35. Morris T.J., Brandon C.A., Horton M.J., Carlson D.S., and Sciote J.J. Maximum shortening velocity and myosin heavy-chain isoform expression in human masseter muscle fibers. J Dent Res 80 (2001) 1845-1848
36. Lipshutz R.J., Fodor S.P., Gingeras T.R., and Lockhart D.J. High density synthetic oligonucleotide arrays. Nat Genet 21 (1999) 20-24
37. Falconer C., Blomgren B., Johansson O., et al. Different organization of collagen fibrils in stress-incontinent women of fertile age. Acta Obstet Gynecol Scand 77 (1998) 87-94
38. Keane D.P., Sims T.J., Abrams P., and Bailey A.J. Analysis of collagen status in premenopausal nulliparous women with genuine stress incontinence. Br J Obstet Gynaecol 104 (1997) 994-998