Evidence for a Genetic Basis of Aging in Two Wild Vertebrate Populations

Current Biology

Volumn 17, Issue 24, 2007, Pages 2136-2142

  Wilson, Alastair J ^a   Nussey, Daniel H ^b   Pemberton, Josephine M ^a   Pilkington, Jill G ^a   Morris, Alison ^b   Pelletier, Fanie ^c   Clutton Brock, Timothy H ^b   Kruuk, Loeske E B ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c NATURAL ENVIRONMENT RESEARCH COUNCIL   (United Kingdom)

Author keywords

EVO_ECOL

Indexed keywords

AGE; AGING; ANIMAL; ARTICLE; BIOLOGICAL MODEL; DEER; EVOLUTION; FEMALE; GENETIC SELECTION; GENETIC VARIABILITY; GENETICS; REPRODUCTION; SHEEP; WILD ANIMAL;

AGE FACTORS; AGING; ANIMALS; ANIMALS, WILD; DEER; EVOLUTION; FEMALE; MODELS, GENETIC; REPRODUCTION; SELECTION (GENETICS); SHEEP, DOMESTIC; VARIATION (GENETICS);

CAENORHABDITIS ELEGANS; INVERTEBRATA; MAMMALIA; VERTEBRATA;

EID: 38349141029     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2007.11.043     Document Type: Article

References (39)

1. Hamilton W.D. The moulding of senescence by natural selection. J. Theor. Biol. 12 (1966) 12-45
2. Medawar P.B. An Unsolved Problem in Biology (1952), H.K. Lewis, London
3. Williams G.C. Pleiotropy, natural selection, and the evolution of senescence. Evolution Int. J. Org. Evolution 11 (1957) 398-411
4. Rose M.R. Evolutionary Biology of Aging (1991), Oxford University Press, Oxford
5. Curtsinger J.W., Fukui H.H., Khazaeli A.A., Kirscher A., Pletcher S.D., Promislow D.E.L., and Tatar M. Genetic variation and aging. Annu. Rev. Genet. 29 (1995) 553-575
6. Hughes K.A., and Reynolds R.M. Evolutionary and mechanistic theories of aging. Annu. Rev. Entomol. 50 (2005) 421-445
7. Wilson R.H., Morgan T.J., and Mackay T.F.C. High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster. Genetics 173 (2006) 1455-1463
8. Charlesworth B., and Hughes K.A. Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence. Proc. Natl. Acad. Sci. USA 93 (1996) 6140-6145
9. Hughes K.A., Alipaz J.A., Drnevich J.M., and Reynolds R.M. A test of evolutionary theories of aging. Proc. Natl. Acad. Sci. USA 99 (2002) 14286-14291
10. Snoke M.S., and Promislow D.E.L. Quantitative genetic tests of recent senescence theory: age-specific mortality and male fertility in Drosophila melanogaster. Heredity 91 (2003) 546-556
11. Clutton-Brock T.H., Guinness F.E., and Albon S.D. Red Deer: Behavior and Ecology of Two Sexes (1982), University of Chicago Press, Chicago
12. In: Clutton-Brock T.H., and Pemberton J.M. (Eds). Soay Sheep: Dynamics and Selection in an Island Population (2004), Cambridge University Press, Cambridge
13. Partridge L., and Barton N.H. Optimality, mutation and the evolution of ageing. Nature 362 (1993) 305-311
14. Williams P.D., Day T., Fletcher Q., and Rowe L. The shaping of senescence in the wild. Trends Ecol. Evol. 21 (2006) 458-463
15. Coulson T., Benton T.G., Lundberg P., Dall S.R.X., Kendall B.E., and Gaillard J.-M. Estimating individual contributions to population growth: Evolutionary fitness in ecological time. Proc. Biol. Sci. 273 (2006) 547-556
16. Pelletier F., Clutton-Brock T.H., Pemberton J.M., Tuljapurkar S., and Coulson T. The evolutionary demography of ecological change: Linking trait variation and population growth. Science 315 (2007) 1571-1574
17. Foerster K., Coulson T., Sheldon B.C., Pemberton J.M., Clutton-Brock T.H., and Kruuk L.E.B. Sexually antagonistic genetic variation for fitness in red deer. Nature 447 (2007) 1107-1110
18. Catchpole E.A., Fan Y., Morgan B.J.T., Clutton-Brock T.H., and Coulson T. Sexual dimorphism, survival and dispersal in red deer. J. Agric. Biol. Environ. Stat. 9 (2004) 1-26
19. Catchpole E.A., Morgan B.J.T., Coulson T.N., Freeman S.N., and Albon S.D. Factors influencing Soay sheep survival. J. R. Stat. Soc. Ser. C Appl. Stat. 49 (2000) 453-472
20. Kruuk L.E.B. Estimating genetic parameters in natural populations using the 'animal model'. Philos. Trans. R. Soc. Lond. B Biol. Sci. 359 (2004) 873-890
21. Meyer K. Estimating covariance functions for longitudinal data using a random regression model. Genet. Sel. Evol. 30 (1998) 221-240
22. Wilson A.J., Kruuk L.E.B., and Coltman D.W. Ontogenetic patterns in heritable variation for body size: using random regression models in a wild ungulate population. Am. Nat. 166 (2005) E177-E192
23. Brommer J.E., Wilson A.J., and Gustafsson L. Exploring the genetics of aging in a wild passerine bird. Am. Nat. 170 (2007) 643-650
24. Pettay J.E., Kruuk L.E.B., Jokela J., and Lummaa V. Heritability and genetic constraints of life-history trait evolution in preindustrial humans. Proc. Natl. Acad. Sci. USA 102 (2005) 2838-2843
25. Charmantier A., Perrins C., McCleery R.H., and Sheldon B.C. Age-dependent genetic variance in a life-history trait in the mute swan. Proc. Biol. Sci. 273 (2006) 225-232
26. Charmantier A., Perrins C., McCleery R.H., and Sheldon B.C. Quantitative genetics of age at reproduction in wild swans: Support for antagonistic pleiotropy models of senescence. Proc. Natl. Acad. Sci. USA 103 (2006) 6587-6592
27. Nussey D.H., Kruuk L.E.B., Donald A., Fowlie M., and Clutton-Brock T.H. The rate of senescence in maternal performance increases with early-life fecundity in red deer. Ecol. Lett. 9 (2006) 1342-1351
28. Nussey D.H., Wilson A.J., Donald A., Pemberton J.M., Clutton-Brock T.H., and Kruuk L.E.B. Testing for genetic trade-offs between early- and late-life reproduction in a wild red deer population. Proc. Biol. Sci (2007) 10.1098/rspb.2007.0986 in press
29. Morrissey M.B., Wilson A.J., Pemberton J.M., and Ferguson M.M. A framework for power and sensitivity analyses for studies of the quantitative genetics of natural populations, and a case study in Soay sheep (Ovis aries). J. Evol. Biol. (2007) in press
30. Baudisch A. Hamilton's indicators of the force of selection. Proc. Natl. Acad. Sci. USA 102 (2005) 8263-8268
31. Rose M.R., Rauser C.L., Benford G., Matos M., and Mueller L.D. Hamilton's forces of selection after forty years. Evolution Int. J. Org. Evolution 61 (2007) 1265-1276
32. Wilson A.J., Pemberton J.M., Pilkington J.G., Clutton-Brock T.H., Coltman D.W., and Kruuk L.E.B. Quantitative genetics of growth and cryptic evolution of body weight in an island population. Evol. Ecol. 21 (2007) 337-356
33. Marshall T.C., Slate J., Kruuk L.E., and Pemberton J.M. Statistical confidence for likelihood-based paternity inference in natural populations. Mol. Ecol. 7 (1998) 639-655
34. Kruuk L.E.B., Slate J., Pemberton J.M., Brotherstone S., Guinness F., and Clutton-Brock T. Antler size in red deer: Heritability and selection but no evolution. Evolution Int. J. Org. Evolution 56 (2002) 1683-1695
35. Kruuk L.E.B., and Hadfield J. How to separate genetic and environmental causes of similarity between relatives. J. Evol. Biol. 20 (2007) 1890-1903
36. Kirkpatrick M., Lofsvold D., and Bulmer M. Analysis of the inheritance, selection and evolution of growth trajectories. Genetics 124 (1990) 979-993
37. Schaeffer L.R. Application of random regression models in animal breeding. Livest. Prod. Sci. 86 (2004) 35-45
38. Fischer T.M., Gilmour A.R., and Van der Werf J.H.J. Computing approximate standard errors for genetic parameters derived from random regression models fitted by average information REML. Genet. Sel. Evol. 36 (2004) 363-369
39. Jaffrezic F., White C.M.S., Thompson R., and Hill W.G. A link function approach to model heterogeneity of residual variances over time in lactation curve analyses. J. Dairy Sci. 83 (2000) 1089-1093