Hepatobiliary excretion and enterohepatic circulation of colchicine in rats

International Journal of Pharmaceutics

Volumn 350, Issue 1-2, 2008, Pages 230-239

  Chen, Yu Jen ^a,b   Huang, Shiou Mei ^b   Liu, Chia Yuan ^a,b   Yeh, Pen Ho ^b   Tsai, Tung Hu ^b,c  

^a MACKAY MEMORIAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c TAIPEI CITY HOSPITAL   (Taiwan)

Author keywords

Colchicine; Cytochrome P450; Enterohepatic circulation; Hepatobiliary excretion; P glycoprotein

Indexed keywords

COLCHICINE; CYCLOSPORIN A; CYTOCHROME P450; GLYCOPROTEIN P; PROADIFEN;

ACUTE DIARRHEA; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BILE LEVEL; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG EXCRETION; DRUG INHIBITION; DRUG LIVER LEVEL; DRUG MEGADOSE; DRUG POTENTIATION; ENTEROHEPATIC CIRCULATION; ENZYME INHIBITION; LIQUID CHROMATOGRAPHY; LOW DRUG DOSE; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; WEIGHT REDUCTION;

ANIMALS; BILE; COLCHICINE; CYCLOSPORINE; DIARRHEA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROHEPATIC CIRCULATION; LIVER; MALE; RATS; RATS, SPRAGUE-DAWLEY; WEIGHT LOSS;

EID: 38349129845     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.08.052     Document Type: Article

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