Modulatory effect of neurosteroids in haloperidol-induced vacuous chewing movements and related behaviors

Psychopharmacology

Volumn 196, Issue 2, 2008, Pages 243-254

  Bishnoi, Mahendra ^a   Chopra, Kanwaljit ^b   Kulkarni, Shrinivas K ^a,b  

^a PANJAB UNIVERSITY   (India)

^b PANJAB UNIVERSITY   (India)

Author keywords

GABA; Jaw tremor; Neurosteroids; NMDA; Orofacial dyskinesia; Tardive dyskinesia; Tongue protrusions; Vacuous chewing movements

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; CATALASE; DOPAMINE; HALOPERIDOL; NEUROLEPTIC AGENT; NEUROSTEROID; NORADRENALIN; PRASTERONE SULFATE; PROGESTERONE; SEROTONIN; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; DRUG EFFECT; FACIES; FEMALE; LIPID PEROXIDATION; MALE; MASTICATION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BEHAVIOR, ANIMAL; CATALASE; CORPUS STRIATUM; DEHYDROEPIANDROSTERONE SULFATE; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DYSKINESIA, DRUG-INDUCED; FEMALE; HALOPERIDOL; HOMOVANILLIC ACID; INJECTIONS, INTRAPERITONEAL; LIPID PEROXIDATION; MALE; MASTICATION; NOREPINEPHRINE; PREGNANOLONE; PREGNENOLONE; PROGESTERONE; RATS; RATS, WISTAR; SEROTONIN; SUPEROXIDE DISMUTASE; SUPEROXIDES;

EID: 38349129042     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-007-0956-z     Document Type: Article

References (65)

1. Andreassen OA, Ferrante RJ, Aamo TO, Beal MF, Jorgensen HA (2003) Oral dyskinesias and histopathological alterations in substantia nigra after long-term haloperidol treatment of old rats. Neuroscience 122(3):717-725
2. Babior BM, Kipner RS, Cerutte JT (1973) Biological defense mechanism: the production by leukocytes of superoxide, a potential bacterial agent. J Clin Invest 52:741-744
3. Barbaccia ML, Affricano D, Purdy RH, Maciocco E, Spiga F, Biggio G (2001) Clozapine, but not haloperidol, increases brain concentrations of neuroactive steroids in the rat. Neuropsychopharmacology 25(4):489-497
4. Bardgett ME, Wrona CT, Newcomer JW, Csernansky JG (1993) Subcortical excitatory amino acid levels after acute and subchronic administration of typical and atypical neuroleptics. Eur J Pharmacol 230:245-250
5. Baulieu EE (1997) Neurosteroids: of the nervous system, by the nervous system, for the nervous system. Recent Prog Horm Res 52:1-32
6. Bishnoi M, Chopra K, Kulkarni SK (2006) Involvement of adenosinergic receptor system in an animal model of tardive dyskinesia and associated behavioural, biochemical and neurochemical changes. Eur J Pharmacol 552(1-3):55-66
7. Bishnoi M, Kumar A, Chopra K, Kulkarni SK (2007a) Comparative neurochemical changes associated with chronic administration of typical and atypical neuroleptics: implications in tardive dyskinesia. Indian J Exp Biol 45(2):175-179
8. Bishnoi M, Chopra K, Kulkarni SK (2007b) Possible anti-oxidant and neuroprotective mechanisms of zolpidem in attenuating typical anti-psychotic-induced orofacial dyskinesia-a biochemical and neurochemical study. Prog Neuropsychopharmacol Biol Psychiatry 31(5):1130-1138
9. Bowlby MR (1993) Pregnenolone sulfate potentiation of N-methyl-d-aspartate receptor channels in hippocampal neurons. Mol Pharmacol 43(5):813-819
10. Burger ME, Fachineto R, Alves A, Callegari L, Rocha JB (2005) Acute reserpine and subchronic haloperidol treatments change synaptosomal brain glutamate uptake and elicit orofacial dyskinesia in rats. Brain Res 1031(2):202-210
11. Burkhardt C, Kelly JP, Lim YH, Filley CM, Parker WD Jr (1993) Neuroleptic medications inhibit complex I of the electron transport chain. Ann Neurol 33:512-517
12. Carlsson M, Carlsson A (1990) Interaction between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease. Trends Neurosci 13:272-276
13. Casey DE (2004) Pathophysiology of antipsychotic drug-induced movement disorders. J Clin Psychiatry 65(Suppl 9):25-28
14. Charalampopoulos I, Dermitzaki E, Vardouli L, Tsatsanis C, Stournaras C, Margioris AN, Gravanis A (2005) Dehydroepiandrosterone sulfate and allopregnanolone directly stimulate catecholamine production via induction of tyrosine hydroxylase and secretion by affecting actin polymerization. Endocrinology 146(8):3309-3318
15. Church WH (2005) Column chromatography analysis of brain tissue: an advanced laboratory exercise for neuroscience majors. J Undergrad Neurosci Educ 3(2):A36-A41
16. Correa M, Wisniecki A, Betz A, Dobson DR, O'Neill MF, O'Neill MJ, Salamone JD (2004) The adenosine A2A antagonist KF17837 reverses the locomotor suppression and tremulous jaw movements induced by haloperidol in rats: possible relevance to parkinsonism. Behav Brain Res 148(1-2):47-54
17. Coyle JT, Puttfarcken P (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science 262:689-695
18. D'Astous M, Morissette M, Tanguay B, Callier S, Di Paolo T (2003) Dehydroepiandrosterone (DHEA) such as 17beta-estradiol prevents MPTP-induced dopamine depletion in mice. Synapse 47:10-14
19. Daly DA, Moghaddam B (1993) Actions of clozapine and haloperidol on the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats. Neurosci Lett 152:61-64
20. Gasior M, Carter RB, Goldberg SR, Witkin JM (1997) Anti convulsant and behavioural effects of neuroactive steroid alone and in conjunction with diazepam. J Pharmacol Exp Ther 282: 543-553
21. Gerlach J, Casey DE (1988) Tardive dyskinesia. Acta Psychiatric Scand 77:369-378
22. Gerlach J, Reys T, Kristjansen P (1978) Effect of baclofen on tardive dyskinesia. Psychopharmacology 56:145-151
23. Gunne LM, Haggestrom JE, Spookiest B (1984) Association with persistent neuroleptic induced dyskinesia of regional changes in the brain GABA synthesis. Nature 309:347-349
24. Gunne LM, Bachus SE, Gale K (1988) Oral movement induced by interference with nigral GABA neurotransmission: relationship to tardive dyskinesia, Exp. Neurology 100:459-469
25. Gupta S, Mosnik D, Black DW, Berry S, Masand PS (1999) Tardive dyskinesia: review of treatments past, present, and future. Ann Clin Psychiatry 11:257-266
26. Irwin RP, Maragakis NJ, Rogawski MA, Purdy RH, Farb DH, Paul SM (1992) Pregnenolone sulfate augments NMDA receptormediated increases in intracellular Ca2+ in cultured rat hippocampalneurons. Neurosci Lett 141:30-34
27. Irwin RP, Lin SZ, Rogawski MA, Purdy RH, Paul SM (1994) Steroid potentiation and inhibition of N-methyl-d-aspartate receptor mediated intracellular Ca++ responses: structure-activity studies. J Pharmacol Exp Ther 271:677-682
28. Ishiwari K, Betz A, Weber S, Felsted J, Salamone JD (2005) Validation of the tremulous jaw movement model for assessment of the motor effects of typical and atypical antipychotics: effects of pimozide (Orap) in rats. Pharmacol Biochem Behav 80(2):351-362
29. Jackson-Lewis V, Przedborski S (1994) Neuroleptic medications inhibit complex I of the electron transport chain. Ann Neurol 35:244-245
30. Kane J (1995) Tardive dyskinesia: epidemiological and clinical presentation. In: Bloom FE, Kupfer DJ (eds) Psychopharmacology: the fourth generation of progress. Raven, New York, pp 1485-1495
31. Karl T, Duffy L, O'brien E, Matsumoto I, Dedova I (2006) Behavioural effects of chronic haloperidol and risperidone treatment in rats. Behav Brain Res 171(2):286-294
32. Kono Y (1978) Generation of superoxide radical during auto-oxidation of hydroxylamine and an assay of superoxide dismutase. Arch Biochem Biophy 186:189-195
33. Lowry OH, Rosenbrought NJ, Farr AL, Randall RJ (1951) Protein measurements with the Folin-phenol reagent. J Biol Chem 193:265-275
34. Luck H (1963) Catalase spectrophotometric method. In: Bergmeyer HU (ed) Methods in enzymatic analysis. Academic Press, New York, pp 885-893
35. Maione S, Berrino L, Vitagliano S, Leyva J, Rossi F (1992) Pregnenolone sulfate increases the convulsant potency of N-methyl-d-aspartate in mice. Eur J Pharmacol 219:477-479
36. Majewska MD, Mienville JM, Vicini S (1988) Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons. Neurosci Lett 90:279-284
37. Majewska MD, Bluet-Pajot MT, Robel P, Baulieu EE (1989) Pregnenolone sulphate antagonizes barbiturate induced hypnosis. Pharmacol Biochem Behav 33:701-703
38. Majewska MD, Schwartz RD (1987) Pregnenolone-sulfate: an endogenous antagonist of the γ-aminobutyric acid receptor complex in brain? Brain Res 404:355-360
39. Mellon SH, Griffin LD, Compagnone NA (2001) Biosynthesis and action of neurosteroids. Brain Res Rev 37:3-12
40. Morrow AL, Suzdak PD, Paul SM (1987) Steroid hormone metabolites potentiate GABA receptor mediated chloride ion influx with nano molar potency. Eur J Pharmacol 142:483-485
41. Mukherjee S, Mahadik SP, Correnti EE, Scheffer R (1994) The antioxidant defense system at the onset of psychosis. Biol Psychiatry 35:701-708
42. Naidu PS, Kulkarni SK (2001) Excitatory mechanisms in neuroleptic-induced vacuous chewing movements (VCMs): possible involvement of calcium and nitric oxide. Behav Pharmacol 12(3):209-216
43. Naidu PS, Singh A, Kulkarni SK (2002) Carvedilol attenuates neuroleptic-induced orofacial dyskinesia: possible antioxidant mechanisms. Br J Pharmacol 136(2):193-200
44. Naidu PS, Singh A, Kulkarni SK (2003) Quercetin, a bioflavonoid attenuated haloperidol induced orofacial dyskinesia. Neuropharmacology 44:1100-1106
45. Olney JW (1990) Excitotoxic amino acids and neuropsychiatric disorders. Annu Rev Pharmacol Toxicol 30:47-71
46. Pastoris A, Cerutti L, Sacco R, De Vecchi L, Sbaffi A (1995) Automated analysis of urinary catecholamines by high-performance liquid chromatography and on-line sample pretreatment. J Chromatogr B Biomed Appl 664(2):287-293
47. Peixoto MF, Abilio VC, Silva RH, Frussa-Filho R (2003) Effects of valproic acid on an animal model of tardive dyskinesia. Behav Brain Res 142:229-233
48. Perry TL, Hansen S, Kish SJ (1979) Effects of chronic administration of antipsychotic drugs on GABA and other amino acids in the mesolimbic area of rat brain. Life Sci 24:283-288
49. Plassart-Schiess E, Baulieu EE (2001) Neurosteroids: recent findings. Brain Res Rev 37:133-140
50. Reddy DS, Castaneda DC, O'Malley BW, Rogawski MA (2004) Anticonvulsant activity of progesterone and neurosteroids in progesterone receptor knockout mice. J Pharmacol Exp Ther 310:230-239
51. Rosengarten H, Bartoszyk GD, Quartermain D, Lin Y (2006) The effect of chronic administration of sarizotan, 5-HT1A agonist/D3/D4 ligand, on haloperidol-induced repetitive jaw movements in rat model of tardive dyskinesia. Prog Neuropsychopharmacol Biol Psychiatry 30(2):273-279
52. Sasaki T, Kennedy JL, Nobrega JN (1997) Localized changes in GABA receptorgated chloride channel in rat brain after long-term haloperidol: relation to vacuous chewing movements. Synapse 25(1):73-9
53. Schwartz PJ, Reaume A, Scott R, Coyle JT (1998) Effects of over- and under-expression of Cu,Zn-superoxide dismutase on toxicity of glutamate analogs in transgenic mouse striatum. Brain Res 789:32-39
54. Seiler N, Grauffel C, Elands J, van den Buuse M, Knodgen B, Sarhan S, Moran P, Gobaille S (1995) Suppression of haloperidol-induced oral dyskinesias in rats by vigabatrin. Pharmacol Biochem Behav 50:181-189
55. Simonian NA, Coyle JT (1996) Oxidative stress in neurodegenerative diseases. Annu Rev Pharmacol Toxicol 36:83-106
56. Thaker GK, Tamminga CA, Alphs LD, Lafferman J, Ferraro TN, Hare TA (1987) Brain γ-aminobutyric acid abnormality in tardive dyskinesia. Reduction in cerebrospinal fluid GABA levels and therapeutic response to GABA agonist treatment. Arch Gen Psychiatry 44:522-529
57. Thaker GK, Nguyen AJ, Tamminga CA (1988) Increased saccadic distractibility in tardive dyskinesia: functional evidence for subcortical GABA dysfunction. Biol Psychiatry 1:49-59
58. Thaker GK, Nguyen JA, Strauss ME, Jacobson R, Kaup BA, Tamminga CA (1990) Clonazepam treatment of tardive dyskinesia: a practical GABA mimetic strategy. Am J Psychiatry 147:445-451
59. Tsai G, Goff DC, Chang RW, Flood J, Baer L, Coyle JT (1998) Markers of glutamatergic neurotransmission and oxidative stress associated with tardive dyskinesia. Am J Psychiatry 155(9):1207-1213
60. Volterra A, Trotti D, Tromba C, Floridi S, Racagni G (1994) Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes. J Neurosci 14:2924-2932
61. Wakerley JB, Richardson CM (1997) The neurosteroid pregnenolone sulphate enhances NMDA-induced phasic firing of vasopressin neurones in the rat supraoptic nucleus. Neurosci Lett 226:123-126
62. Wills ED (1966) Mechanism of lipid peroxide formation in animal tissues. Biochem J 99:667-676
63. Wojtal K, Trojnar MK, Czuczwar SJ (2006) Endogenous neuroprotective factors: neurosteroids. Pharmacol Rep 58:335-340
64. Wu FS, Gibbs TT, Farb DH (1990) Inverse modulation of gamma amino butyric acid and glycine-induced currents by progesterone. Mol Pharmacol 37:597-602
65. Wu FS, Gibbs TT, Farb DH (1991) Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-d-aspartate receptor. Mol Pharmacol 40:333-336