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Volumn 196, Issue 2, 2008, Pages 958-965

The administration of estrogens, combined with anti-androgens, has beneficial effects on the hormonal features and asymmetric dimethyl-arginine levels, in women with the polycystic ovary syndrome

Author keywords

ADMA; Endothelin 1; Estrogens; PCOS

Indexed keywords

ANDROGEN; ANTIANDROGEN; CONJUGATED ESTROGEN; CYPROTERONE ACETATE; DESOGESTREL PLUS ETHINYLESTRADIOL; ENDOTHELIN 1; ESTRADIOL; ESTROGEN; ESTROPAUSE; ETHINYLESTRADIOL; GLUCOSE; GONADOTROPIN; GYNOFEN 35; INSULIN; N(G),N(G) DIMETHYLARGININE; PROLACTIN; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 38349111105     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2007.03.002     Document Type: Article
Times cited : (41)

References (39)
  • 2
    • 23744488235 scopus 로고    scopus 로고
    • 4-androstenedione levels in lean women with polycystic ovary syndrome
    • 4-androstenedione levels in lean women with polycystic ovary syndrome. Fertil Steril 84 (2005) 538-540
    • (2005) Fertil Steril , vol.84 , pp. 538-540
    • Panidis, D.1    Farmakiotis, D.2    Rousso, D.3
  • 3
    • 0032586939 scopus 로고    scopus 로고
    • Polymorphism TC (-34bp) of gene CYP17 promoter in Greek patients with polycystic ovary syndrome
    • Diamanti-Kandarakis E., Bartzis M.I., Zapanti E.D., et al. Polymorphism TC (-34bp) of gene CYP17 promoter in Greek patients with polycystic ovary syndrome. Fertil Steril 71 (1999) 431-435
    • (1999) Fertil Steril , vol.71 , pp. 431-435
    • Diamanti-Kandarakis, E.1    Bartzis, M.I.2    Zapanti, E.D.3
  • 4
    • 0024437305 scopus 로고
    • Profound peripheral insulin resistance, independent of obesity, in the polycystic ovary syndrome
    • Dunaif A., Futterweit W., Segal K.R., and Dobrjansky A. Profound peripheral insulin resistance, independent of obesity, in the polycystic ovary syndrome. Diabetes 38 (1989) 1165-1174
    • (1989) Diabetes , vol.38 , pp. 1165-1174
    • Dunaif, A.1    Futterweit, W.2    Segal, K.R.3    Dobrjansky, A.4
  • 5
    • 0030783316 scopus 로고    scopus 로고
    • Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens
    • Nestler J.E., and Jakubowicz D.J. Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens. J Clin Endocrinol Metab 82 (1997) 4075-4079
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4075-4079
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 6
    • 0026028184 scopus 로고
    • A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome
    • Nestler J.E., Powers L.P., Matt D.W., et al. A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome. J Clin Endocrinol Metab 72 (1991) 83-89
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 83-89
    • Nestler, J.E.1    Powers, L.P.2    Matt, D.W.3
  • 7
    • 0027080247 scopus 로고
    • Polycystic ovary syndrome and risk for myocardial infarction: evaluated from a risk factor model based prospective population study of women
    • Dahlgren E., Janson P.O., Johansson Lapidus L., and Oden A. Polycystic ovary syndrome and risk for myocardial infarction: evaluated from a risk factor model based prospective population study of women. Acta Obstet Gynecol Scand 71 (1992) 599-604
    • (1992) Acta Obstet Gynecol Scand , vol.71 , pp. 599-604
    • Dahlgren, E.1    Janson, P.O.2    Johansson Lapidus, L.3    Oden, A.4
  • 8
    • 33644558330 scopus 로고    scopus 로고
    • Cardiovascular disease in the polycystic ovary syndrome: New insights and perspectives
    • Cussons A.J., Stuckey B.G.A., and Watts G.F. Cardiovascular disease in the polycystic ovary syndrome: New insights and perspectives. Atherosclerosis 185 (2006) 227-239
    • (2006) Atherosclerosis , vol.185 , pp. 227-239
    • Cussons, A.J.1    Stuckey, B.G.A.2    Watts, G.F.3
  • 9
    • 0035182383 scopus 로고    scopus 로고
    • Cardiovascular risk in adolescent and young adult obese females with PCOS
    • Macut D., Micic D., Cvijovic G., et al. Cardiovascular risk in adolescent and young adult obese females with PCOS. J Pediatr Endocrinol Metab 5 (2001) 1353-1359
    • (2001) J Pediatr Endocrinol Metab , vol.5 , pp. 1353-1359
    • Macut, D.1    Micic, D.2    Cvijovic, G.3
  • 10
    • 0344286476 scopus 로고    scopus 로고
    • Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome
    • Ehrmann D.A., Barnes R.B., Rosenfield R.L., Cavaghan M.K., and Imperial J. Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care 22 (1999) 141-146
    • (1999) Diabetes Care , vol.22 , pp. 141-146
    • Ehrmann, D.A.1    Barnes, R.B.2    Rosenfield, R.L.3    Cavaghan, M.K.4    Imperial, J.5
  • 11
    • 0035853088 scopus 로고    scopus 로고
    • Polycystic ovary syndrome is associated with endothelial dysfunction
    • Paradisi G., Steinberg H.O., Hempfling A., et al. Polycystic ovary syndrome is associated with endothelial dysfunction. Circulation 103 (2001) 1410-1415
    • (2001) Circulation , vol.103 , pp. 1410-1415
    • Paradisi, G.1    Steinberg, H.O.2    Hempfling, A.3
  • 12
    • 8744310157 scopus 로고    scopus 로고
    • Endothelial dysfunction in young women with polycystic ovary syndrome: relationship with insulin resistance and low-grade chronic inflammation
    • Tarkun I., Arslan B.C., Canturk Z., et al. Endothelial dysfunction in young women with polycystic ovary syndrome: relationship with insulin resistance and low-grade chronic inflammation. J Clin Endocrinol Metab 89 (2004) 5592-5596
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 5592-5596
    • Tarkun, I.1    Arslan, B.C.2    Canturk, Z.3
  • 13
    • 0036170819 scopus 로고    scopus 로고
    • Altered vascular function in young women with polycystic ovary syndrome
    • Kelly C.J., Speirs A., Gould G.W., et al. Altered vascular function in young women with polycystic ovary syndrome. J Clin Endocrinol Metab 87 (2002) 742-746
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 742-746
    • Kelly, C.J.1    Speirs, A.2    Gould, G.W.3
  • 14
    • 0034748334 scopus 로고    scopus 로고
    • Increased endothelin-1 levels in women with polycystic ovary syndrome and the beneficial effect of metformin therapy
    • Diamanti-Kandarakis E., Spina G., Kouli C., and Migdalis I. Increased endothelin-1 levels in women with polycystic ovary syndrome and the beneficial effect of metformin therapy. J Clin Endocrinol Metab 86 (2001) 4666-4673
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4666-4673
    • Diamanti-Kandarakis, E.1    Spina, G.2    Kouli, C.3    Migdalis, I.4
  • 15
    • 0023859136 scopus 로고
    • A novel potent vasoconstrictor peptide produced by vascular endothelial cells
    • Yanagisawa M., Kurihara H., Kimura S., et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332 (1988) 411-415
    • (1988) Nature , vol.332 , pp. 411-415
    • Yanagisawa, M.1    Kurihara, H.2    Kimura, S.3
  • 16
    • 4544265733 scopus 로고    scopus 로고
    • Early impairment of endothelial structure and function in young normal-weight women with polycystic ovary syndrome
    • Orio Jr. F., Palomba S., Cascella T., et al. Early impairment of endothelial structure and function in young normal-weight women with polycystic ovary syndrome. J Clin Endocrinol Metab 89 (2004) 4588-4593
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 4588-4593
    • Orio Jr., F.1    Palomba, S.2    Cascella, T.3
  • 17
    • 24344448639 scopus 로고    scopus 로고
    • Predictors of endothelial dysfunction in young women with polycystic ovary syndrome
    • Kravariti M., Naka K.N., Kalantaridou S.N., et al. Predictors of endothelial dysfunction in young women with polycystic ovary syndrome. J Clin Endocrinol Metab 90 (2005) 5088-5095
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5088-5095
    • Kravariti, M.1    Naka, K.N.2    Kalantaridou, S.N.3
  • 18
    • 0026548912 scopus 로고
    • Accumulation of an endogenous inhibitor of NO synthesis in chronic renal failure
    • Vallance P., Leone A., Calver A., Collier J., and Moncada S. Accumulation of an endogenous inhibitor of NO synthesis in chronic renal failure. Lancet 339 (1992) 572-575
    • (1992) Lancet , vol.339 , pp. 572-575
    • Vallance, P.1    Leone, A.2    Calver, A.3    Collier, J.4    Moncada, S.5
  • 19
    • 0842347848 scopus 로고    scopus 로고
    • The emerging role of ADMA as a novel cardiovascular risk factor
    • Böger R.H. The emerging role of ADMA as a novel cardiovascular risk factor. Cardiovasc Res 59 (2003) 824-833
    • (2003) Cardiovasc Res , vol.59 , pp. 824-833
    • Böger, R.H.1
  • 20
    • 0035936390 scopus 로고    scopus 로고
    • Risk of acute coronary events and serum concentrations of asymmetric dimethylarginine
    • Valkonen V.P., Päivä H., Salonen J.T., et al. Risk of acute coronary events and serum concentrations of asymmetric dimethylarginine. Lancet 358 (2001) 2127-2128
    • (2001) Lancet , vol.358 , pp. 2127-2128
    • Valkonen, V.P.1    Päivä, H.2    Salonen, J.T.3
  • 21
    • 1942438521 scopus 로고    scopus 로고
    • Assymetrical dimethylarginine. The U{combining double acute accent}ber Marker?
    • Cooke J. Assymetrical dimethylarginine. The U{combining double acute accent}ber Marker?. Circulation 109 (2004) 1813-1819
    • (2004) Circulation , vol.109 , pp. 1813-1819
    • Cooke, J.1
  • 22
    • 27744604586 scopus 로고    scopus 로고
    • Elevated levels of asymmetric dimethylarginine (ADMA) as a marker of cardiovascular disease and mortality
    • Böger R.H., Maas R., Schulze F., and Schwedhelm E. Elevated levels of asymmetric dimethylarginine (ADMA) as a marker of cardiovascular disease and mortality. Clin Chem Lab Med 43 (2005) 1124-1129
    • (2005) Clin Chem Lab Med , vol.43 , pp. 1124-1129
    • Böger, R.H.1    Maas, R.2    Schulze, F.3    Schwedhelm, E.4
  • 23
    • 0036460659 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine (ADMA): a potential link between endothelial dysfunction and cardiovascular diseases in insulin resistance syndrome?
    • Chan N.N., and Chan J.C.N. Asymmetric dimethylarginine (ADMA): a potential link between endothelial dysfunction and cardiovascular diseases in insulin resistance syndrome?. Diabetologia 45 (2002) 1609-1616
    • (2002) Diabetologia , vol.45 , pp. 1609-1616
    • Chan, N.N.1    Chan, J.C.N.2
  • 24
    • 0346186090 scopus 로고    scopus 로고
    • Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome PCOS
    • The Rotterdam ESHRE/ASRM-sponsored PCOS Consensus Workshop Group
    • The Rotterdam ESHRE/ASRM-sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome PCOS. Hum Reprod 19 (2004) 41-47
    • (2004) Hum Reprod , vol.19 , pp. 41-47
  • 25
    • 33748708041 scopus 로고    scopus 로고
    • Inflammatory and endothelial markers in women with polycystic ovary syndrome
    • Diamanti-Kandarakis E., Alexandraki K., Piperi C., et al. Inflammatory and endothelial markers in women with polycystic ovary syndrome. Eur J Clin Invest 36 (2006) 691-697
    • (2006) Eur J Clin Invest , vol.36 , pp. 691-697
    • Diamanti-Kandarakis, E.1    Alexandraki, K.2    Piperi, C.3
  • 26
    • 0027260899 scopus 로고
    • Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia
    • Kourembanas S., McQuillan L.P., and Leung G. Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia. J Clin Invest 92 (1993) 99-104
    • (1993) J Clin Invest , vol.92 , pp. 99-104
    • Kourembanas, S.1    McQuillan, L.P.2    Leung, G.3
  • 27
    • 0036671662 scopus 로고    scopus 로고
    • Endothelin stimulates an endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine, in experimental heart failure
    • Ohnishi M., Wada A., Tsutamoto T., et al. Endothelin stimulates an endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine, in experimental heart failure. Clin Sci 103 (2002) 241S-244S
    • (2002) Clin Sci , vol.103
    • Ohnishi, M.1    Wada, A.2    Tsutamoto, T.3
  • 28
    • 33646155569 scopus 로고    scopus 로고
    • Plasma markers of NO synthase activity in women after ovarian hyperstimulation: influence of estradiol on ADMA
    • Cevic D., Unay O., Durmusoglu F., Yurdun T., and Bilsel A.S. Plasma markers of NO synthase activity in women after ovarian hyperstimulation: influence of estradiol on ADMA. Vasc Med 11 (2006) 7-12
    • (2006) Vasc Med , vol.11 , pp. 7-12
    • Cevic, D.1    Unay, O.2    Durmusoglu, F.3    Yurdun, T.4    Bilsel, A.S.5
  • 29
    • 0141618308 scopus 로고    scopus 로고
    • Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine
    • Holden D.P., Cartwright J.E., Nussey S.S., and Whitley G. Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine. Circulation 108 (2003) 1575-1580
    • (2003) Circulation , vol.108 , pp. 1575-1580
    • Holden, D.P.1    Cartwright, J.E.2    Nussey, S.S.3    Whitley, G.4
  • 30
    • 0141787963 scopus 로고    scopus 로고
    • Effect of hormone replacement therapy on plasma concentrations of the cardiovascular risk factor asymmetric dimethylarginine: a randomized, placebo-controlled 12-week study in healthy early post-menopausal women
    • Post M.S., Verhoeven M.O., Van der Mooren M.J., et al. Effect of hormone replacement therapy on plasma concentrations of the cardiovascular risk factor asymmetric dimethylarginine: a randomized, placebo-controlled 12-week study in healthy early post-menopausal women. J Clin Endocrinol Metab 88 (2003) 4221-4246
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4221-4246
    • Post, M.S.1    Verhoeven, M.O.2    Van der Mooren, M.J.3
  • 31
    • 33646673128 scopus 로고    scopus 로고
    • Estrogen replacement effectively improves the accelerated intimal hyperplasia following ballon injury of carotid artery in the ovariectomized rats
    • Ishibahshi T., Obayashi S., Sakamoto S., et al. Estrogen replacement effectively improves the accelerated intimal hyperplasia following ballon injury of carotid artery in the ovariectomized rats. J Cardiovasc Pharmacol 47 (2006) 37-45
    • (2006) J Cardiovasc Pharmacol , vol.47 , pp. 37-45
    • Ishibahshi, T.1    Obayashi, S.2    Sakamoto, S.3
  • 32
    • 0031978591 scopus 로고    scopus 로고
    • Plasma concentration of asymmetric dimethylarginine, a natural inhibitor of nitric oxide synthase, in normal pregnancy and preeclampsia
    • Holden D.P., Fickling S., Whitley G., and Nussey S.S. Plasma concentration of asymmetric dimethylarginine, a natural inhibitor of nitric oxide synthase, in normal pregnancy and preeclampsia. Am J Obst Gynecol 178 (1998) 551-556
    • (1998) Am J Obst Gynecol , vol.178 , pp. 551-556
    • Holden, D.P.1    Fickling, S.2    Whitley, G.3    Nussey, S.S.4
  • 33
    • 33750865905 scopus 로고    scopus 로고
    • 17β-Estradiol reduces vasoconstriction in endothelium-denuded rat aortas through inducible NOS
    • Binco J., and Majewski H. 17β-Estradiol reduces vasoconstriction in endothelium-denuded rat aortas through inducible NOS. Am J Physiol 43 (1998) H853-H859
    • (1998) Am J Physiol , vol.43
    • Binco, J.1    Majewski, H.2
  • 34
    • 0028987629 scopus 로고
    • Detection of NG,NG-dimethylarginine dimethylaminohydrolase in human tissues using a monoclonal antibody
    • Kimoto M., Whitley G.S., Tsuji H., and Ogawa T. Detection of NG,NG-dimethylarginine dimethylaminohydrolase in human tissues using a monoclonal antibody. J Biochem (Tokyo) 117 (1995) 237-238
    • (1995) J Biochem (Tokyo) , vol.117 , pp. 237-238
    • Kimoto, M.1    Whitley, G.S.2    Tsuji, H.3    Ogawa, T.4
  • 35
    • 0033594888 scopus 로고    scopus 로고
    • Novel mechanism for endothelial dysfunction. Dysregulation of dimethylarginine dimethylaminohydrolase
    • Ito A., Tsao P.S., Adimoolam S., et al. Novel mechanism for endothelial dysfunction. Dysregulation of dimethylarginine dimethylaminohydrolase. Circulation 99 (1999) 3092-3095
    • (1999) Circulation , vol.99 , pp. 3092-3095
    • Ito, A.1    Tsao, P.S.2    Adimoolam, S.3
  • 36
    • 1542270312 scopus 로고    scopus 로고
    • Metabolic and endocrine effects of treatment with peroral or transdermal oestrogens in conjuction with peroral cyproterone acetate in women with polycystic ovary syndrome
    • Vrbίková J., Stanická S., Dvořáková K., et al. Metabolic and endocrine effects of treatment with peroral or transdermal oestrogens in conjuction with peroral cyproterone acetate in women with polycystic ovary syndrome. Eur J Endocrinol 150 (2004) 215-223
    • (2004) Eur J Endocrinol , vol.150 , pp. 215-223
    • Vrbková, J.1    Stanická, S.2    Dvořáková, K.3
  • 37
    • 31644449390 scopus 로고    scopus 로고
    • Effects of two forms of combined oral contraceptives on carbohydrate metabolism in adolescents with polycystic ovary syndrome
    • Mastorakos G., Koliopoulos C., Deligeoroglou E., Diamanti-Kandarakis E., and Creatsas G. Effects of two forms of combined oral contraceptives on carbohydrate metabolism in adolescents with polycystic ovary syndrome. Fertil Steril 85 (2006) 420-427
    • (2006) Fertil Steril , vol.85 , pp. 420-427
    • Mastorakos, G.1    Koliopoulos, C.2    Deligeoroglou, E.3    Diamanti-Kandarakis, E.4    Creatsas, G.5
  • 38
    • 33646178955 scopus 로고    scopus 로고
    • Reciprocal relationships between insulin resistance and endothelial dysfunction. Molecular and pathophysiological mechanisms
    • Kim J., Montagnani M., Koh K.K., and Quon M.J. Reciprocal relationships between insulin resistance and endothelial dysfunction. Molecular and pathophysiological mechanisms. Circulation 113 (2006) 1888-1904
    • (2006) Circulation , vol.113 , pp. 1888-1904
    • Kim, J.1    Montagnani, M.2    Koh, K.K.3    Quon, M.J.4
  • 39
    • 0036675187 scopus 로고    scopus 로고
    • The role of lifestyle modification in polycystic ovary syndrome
    • Norman R.J., Davies M.J., Lord J., and Moran L. The role of lifestyle modification in polycystic ovary syndrome. Trends Endocrinol Metab 13 (2002) 251-257
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 251-257
    • Norman, R.J.1    Davies, M.J.2    Lord, J.3    Moran, L.4


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