A pleiotropic QTL on 2p influences serum Lp-PLA2 activity and LDL cholesterol concentration in a baboon model for the genetics of atherosclerosis risk factors

Atherosclerosis

Volumn 196, Issue 2, 2008, Pages 667-673

  Vinson, A ^a   Mahaney, M C ^a,b   Cox, L A ^a,b   Rogers, J ^a,b   VandeBerg, J L ^a,b   Rainwater, D L ^a  

^a SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

^b SOUTHWEST NATIONAL PRIMATE RESEARCH CENTER   (United States)

Author keywords

Baboon; Bivariate; Genome scan; LDL cholesterol; Lp PLA2; Pleiotropy

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; BABOON; BIVARIATE ANALYSIS; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CHROMOSOMAL LOCALIZATION; CHROMOSOME 2P; CHROMOSOME ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE ACTIVITY; GENE LOCUS; GENETIC CORRELATION; GENETIC LINKAGE; GENETIC TRAIT; GENETIC VARIABILITY; GENOME; GENOTYPE PHENOTYPE CORRELATION; MALE; MAXIMUM LIKELIHOOD METHOD; NONHUMAN; ORTHOLOGY; PEDIGREE ANALYSIS; PLEIOTROPY; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; STATISTICAL SIGNIFICANCE;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ANIMALS; ATHEROSCLEROSIS; CHOLESTEROL, LDL; DISEASE MODELS, ANIMAL; FEMALE; MALE; MULTIVARIATE ANALYSIS; PAPIO HAMADRYAS; QUANTITATIVE TRAIT LOCI; RISK FACTORS;

EID: 38349095309     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2007.07.014     Document Type: Article

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