Specific visuomotor deficits due to alcohol intoxication: Evidence from the pro- and antisaccade paradigms

Psychopharmacology

Volumn 196, Issue 2, 2008, Pages 201-210

  Vorstius, Christian ^a   Radach, Ralph ^a   Lang, Alan R ^a   Riccardi, Christina J ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Alcohol; Anti saccade; Inhibition; Intoxication; Pro saccade

Indexed keywords

ALCOHOL;

ADULT; ALCOHOL INTOXICATION; ANALYTICAL ERROR; ARTICLE; CLINICAL ARTICLE; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; EYE MOVEMENT CONTROL; EYE MOVEMENT DISORDER; HUMAN; PRIORITY JOURNAL; SACCADIC EYE MOVEMENT; VISUOMOTOR COORDINATION;

ADULT; ALCOHOLIC INTOXICATION; ANALYSIS OF VARIANCE; BREATH TESTS; ETHANOL; EYE MOVEMENT MEASUREMENTS; FEMALE; HUMANS; MALE; PHOTIC STIMULATION; PSYCHOMOTOR PERFORMANCE; REACTION TIME; SACCADES; VISUAL PERCEPTION;

EID: 38349091356     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-007-0954-1     Document Type: Article

References (51)

1. Abroms BD, Gottlob LR, Fillmore MT (2006) Alcohol effects on inhibitory control of attention: distinguishing between intentional and automatic mechanisms. Psychopharmacology 188:324-334
2. Baloh RW, Sharma S, Moskowitz H, Griffith R (1979) Effect of alcohol and marijuana on eye movements. Aviat Space Environ Med 50:18-23
3. Bell AH, Everling S, Munoz DP (2000) Influence of stimulus eccentricity and direction on characteristics of pro- and antisaccades in non-human primates. J Neurophysiol 84:2595-2604
4. Blekher T, Beard JD, O'Connor S, Orr WE, Ramchandani VA, Miller K, Yee RD, Li TK (2002) Response of saccadic eye movements to alcohol in African American and non-Hispanic white college students. Alcohol Clin Exp Res 26:232-238
5. Collewijn H, Erkelens CJ, Steinman RM (1988) Binocular co-ordination of human horizontal saccadic eye movements. J Physiol 404:157-182
6. Crevits L, Hanse MC, Tummers P, Van Maele G (2000) Antisaccades and remembered saccades in mild traumatic brain injury. J Neurol 247:179-182
7. Curtin JJ, Lang AR, Patrick CJ, Stritzke WGK (1998) Alcohol and fear potentiated startle: the role of competing cognitive demands in the stress-reducing effects of intoxication. J Abnorm Psychology 107:547-565
8. Davies DL, Alkana RL (2001) Ethanol enhances GABAA receptor function in short sleep and long sleep mouse brain membranes. Alcohol Clin Exp Res 25:478-483
9. Dorris MC, Munoz DP (1995) A neural correlate for the gap effect on saccadic reaction times in the monkey. J Neurophysiol 73:2558-2562
10. Easdon CM, Vogel-Sprott M (2000) Alcohol and behavioral control: impaired response inhibition and flexibility in social drinkers. Exp Clin Psychopharmacol 8(3):387-394
11. Edelman JA, Valenzuela N, Barton JJS (2006) Antisaccade velocity, but not latency, results from lack of saccade visual guidance. Vis Res 46:1411-1421
12. Enderle JD (2002) Neural control of saccades. In: Hyönä J, Radach R, Deubel H (eds.). The mind's eye: cognitive and applied aspects of eye movements. pp 21-49. Elsevier Science, Amsterdam
13. Everling S, Fischer B (1998) The antisaccade: a review of basic research and clinical studies. Neuropsychologia 36:885-899
14. Everling S, Dorris MC, Klein RM, Munoz DP (1999) Role of primate superior colliculus in preparation and execution of antisaccades and pro-saccades. J Neurosci 19:2740-2754
15. Fillmore MT (2003) Drug abuse as a problem of impaired control: current approaches and findings. Behav Cogn Neurosci Rev 2:179-197
16. Fillmore MT, Vogel-Sprott M (1999) An alcohol model of impaired inhibitory control and its treatment in humans. Exp Clin Psychopharmacol 7:49-55
17. Fillmore MT, Vogel-Sprott M (2000) Response inhibition under alcohol: effects of cognitive and motivational conflict. J Stud Alcohol 61:239-246
18. Findlay JM, Gilchrist ID (2003) Active vision: the psychology of looking and seeing. Oxford University Press, Oxford
19. Findlay JM, Walker R (1999) A model of saccade generation based on parallel processing and competitive inhibition. Behav Brain Sci 22:661-721
20. Forbes K, Klein R (1996) The magnitude of the fixation offset effect with endogenously and exogenously controlled saccade. J Cogn Neurosci 8:344-352
21. Gale BW, Abel LA, Christian JC, Sorbel J, Ye RD (1996) Saccadic characteristics of monozygotic and dizygotic twins before and after alcohol administration. Invest Ophthalmol Vis Sci 37(2):339-344
22. Guitton D, Buchtel HA, Douglas RM (1985) Frontal lobe lesions in man cause difficulties in suppressing reflexive glances and in generating goal-directed saccades. Exp Brain Res 58:455-472
23. Hallett PE (1978) Primary and secondary saccades to goals defined by instructions. Vis Res 18:1279-1296
24. Holloway F (1994) Low-dose alcohol effects on human behavior and performance: a review of post-1984 research. DOT/FAA/AM-94/24 Technical Report. Washington, DC: Office of Aviation Medicine
25. Jantti V, Lang AH, Keskinen E, Lehtinen I, Pakkanen A (1983) Acute effects of intravenously given alcohol on saccadic eye movements and subjective evaluations of intoxication. Psychopharmacology 79:251-255
26. Khan SA, Ford K, Timney B, Everling S (2003) Effects of ethanol on anti-saccade task performance. Exp Brain Res 150:68-74
27. Kingstone A, Klein RM (1993) Visual offset facilitates saccade latency: does pre-disengagement of attention mediate this gap effect? J Exp Psychol Hum Percept Perform 19:251-65
28. Krull KR, Smith LT, Parsons OA (1994) Simple reaction time event-related potentials: effects of alcohol and diazepam. Prog Neuropsychopharmacol Biol Psychiatry 18:1247-1260
29. Lehtinen I, Lang AH, Jantti V, Keskinen E (1979) Acute effects of alcohol on saccadic eye movements. Psychopharmacology 63:17-23
30. Leigh RJ, Kennard C (2004) Using saccades as a research tool in the clinical Neurosciences. Brain 127:460-477
31. Liu Y, Higuchi S, Motohashi Y (2000) Time-of-day effects of ethanol consumption on EEG topography and cognitive eventrelated potential in adult males. J Physiol Anthropol Appl Hum Sci 19:249-254
32. Massen C (2004) Parallel programming of exogenous and endogenous components in the antisaccade task. Q J Exp Psychol A 57:475-498
33. Moser A, Heide W, Kompf D (1998) The effect of oral ethanol consumption on eye movements in healthy volunteers. J Neurol 245:542-550
34. Mulvihill LE, Skilling TA, Vogel-Sprott M (1997) Alcohol and the ability to inhibit behavior in men and women. J Stud Alcohol 58:600-605
35. Munoz DP, Everling S (2004) Look away: the anti-saccade task and the voluntary control of eye movement. Nature reviews. Neuroscience 5(3):218-228
36. Pierrot-Deseilligny C, Muri RM, Ploner CJ, Gaymard B, Demeret S, Rivaud-Pechoux S (2003) Decisional role of the dorsolateral prefrontal cortex in ocular motor behaviour. Brain 126(6):1460-1473
37. Ploner CJ, Tschirch A, Ostendorf F, Dick S, Gaymard BM, Rivaud-Pechoux S, Sporkert F, Pragst F, Stadelmann AM (2002) Oculomotor effects of delta-9-tetrahydrocannabinol in humans: implications for the functional neuroanatomy of the brain cannabinoid system. Cereb Cortex 12:1016-1023
38. Reuter B, Kathmann N (2004) Using saccade tasks as a tool to analyze executive dysfunctions in schizophrenia. Acta Psychol 115(2-3):255-269
39. Ross LE, Ross SM (1980) Saccade latency and warning signals: stimulus onset, offset and change as warning events. Percept Psychophys 27:251-257
40. Ross SM, Ross LE (1981) Saccade latency and warning signals: effects of auditory and visual offset and onset. Percept Psychophys 29:429-437
41. Saslow MG (1967) Effects of components of displacement-step stimuli upon latency for saccadic eye movement. J Opt Soc Am 57(8):1024-1029
42. Scudder CA, Kaneko CRS, Fuchs AF (2002) The brainstem burst generator for saccadic eye movements. A modern synthesis. Exp Brain Res 142:439-462
43. Schlag-Rey M, Amador N, Sanchez H, Schlag J (1997) Antisaccade performance predicted by neuronal activity in the supplementary eye field. Nature 390:398-401
44. Selzer ML, Vinokur A, Rooijen L (1975) A self-administered Short Michigan Alcoholism Screening Test (SMAST). J Stud Alcohol 36:117-126
45. Testa M, Fillmore M, Norris J, Abbey A, Curtin J, Leonard K, Mariano K, Thomas M, Nomenson K, George W, VanZile-Tamsen C, Livingston J, Saenez C, Buck P, Zawacki T, Parkhill M, Jacques A, Hayman L (2006) Understanding alcohol expectancy effects: revisiting the placebo condition. Alcohol Clin Exp Res 30:339-348
46. Vassallo S, Abel LA (2002) Ethanol effects on volitional versus reflexive saccades. Clin Exp Ophthalmol 30:208-212
47. Walker R, McSorley E (2006) The parallel programming of voluntary and reflexive saccades. Vis Res 26:2082-2093
48. Walker R, Kentridge RW, Findlay JM (1995) Independent contributions of the orienting of attention, fixation offset and bilateral stimulation on human saccadic latency. Exp Brain Res 103(2):294-310
49. Wang MY, Rampil IJ, Kendig JJ (1999) Ethanol directly depresses AMPA and NMDA glutamate currents in spinal cord motor neurons independent of actions on GABAA or glycine receptors. J Pharmacol Exp Ther 290(1):362-367
50. Wegner AJ, Fahle M (1999) Alcohol and visually guided saccades: gap effect and predictability of target location. Psychopharmacology 146:24-32
51. Wurtz RH, Goldberg ME (1989) The neurobiology of saccadic eye movements. Elsevier, Amsterdam