Human-murine transthyretin heterotetramers are kinetically stable and non-amyloidogenic: A lesson in the generation of transgenic models of diseases involving oligomeric proteins

Journal of Biological Chemistry

Volumn 283, Issue 4, 2008, Pages 2098-2107

  Reixach, Natàlia ^a,c   Foss, Ted R ^a   Santelli, Eugenio ^b   Pascual, Jaime ^b   Kelly, Jeffery W ^a   Buxbaum, Joel N ^a,c  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b BURNHAM INSTITUTE   (United States)

^c MEM 230 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; GENE EXPRESSION; OLIGOMERS;

AGGREGATION PRECURSORS; AMYLOIDOGENESIS; HETEROTETRAMERS;

PROTEINS;

AMYLOID; OLIGOMER; PREALBUMIN; TETRAMER;

ARTICLE; CRYSTAL STRUCTURE; HUMAN; KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; TRANSGENICS;

AMYLOID; ANIMALS; CRYSTALLOGRAPHY, X-RAY; HUMANS; KINETICS; MICE; PREALBUMIN; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; RECOMBINANT PROTEINS; SPECIES SPECIFICITY;

MURINAE; MUS;

EID: 38349085003     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708028200     Document Type: Article

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