Endometrial explant culture for characterizing equine endometritis

American Journal of Reproductive Immunology

Volumn 59, Issue 2, 2008, Pages 105-117

  Nash, Deborah ^a,b   Lane, Elizabeth ^c   Herath, Shan ^a   Martin Sheldon, I ^a  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b ABERYSTWYTH UNIVERSITY   (United Kingdom)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Escherichia coli; Fmale genital tract; Postaglandins; Spermatozoa; Streptococcus zooepidemicus

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; OXYTOCIN; POLYMYXIN B; PROSTAGLANDIN F2 ALPHA;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; ENDOMETRIOSIS; ESCHERICHIA COLI; EXPLANT; FEMALE; FEMALE INFERTILITY; FOLLICULAR PHASE; HISTOPATHOLOGY; HORSE DISEASE; LUTEAL PHASE; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; SPERMATOZOON; STREPTOCOCCUS EQUI ZOOEPIDEMICUS; TISSUE CULTURE; TISSUE REACTION; UTERUS HORN;

ANIMALS; ANTI-BACTERIAL AGENTS; DINOPROST; ENDOMETRITIS; ENDOMETRIUM; ESTROUS CYCLE; FEMALE; HISTOCYTOCHEMISTRY; HORSE DISEASES; HORSES; LIPOPOLYSACCHARIDES; OXYTOCIN; POLYMYXIN B; PROGESTERONE; STREPTOCOCCUS EQUI; TISSUE CULTURE TECHNIQUES;

EID: 38349078248     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/j.1600-0897.2007.00548.x     Document Type: Article

References (43)

1. Watson ED: Post-breeding endometritis in the mare. Anim Reprod Sci 2000; 61: 221-232.
2. Traub-Dargatz JL, Salman MD, Voss JL: Medical problems of adult horses, as ranked by equine practitioners. J Am Vet Med Assoc 1991; 198: 1745-1747.
3. LeBlanc MM: Persistent mating induced endometritis in the mare: pathogenesis, diagnosis and treatment. In Recent Advances in Equine Reproduction, BA Ball (ed), New York, International Veterinary Information Service, 2003.
4. Pycock JF, Newcombe J: The relationship between intraluminal fluid, endometritis, and pregnancy rate in the mare. Equine Pract 1996; 18: 19-22.
5. Troedsson MH, Loset K, Alghamdi AM, Dahms B, Crabo BG: Interaction between equine semen and the endometrium: The inflammatory response to semen. Anim Reprod Sci 2001; 68: 273-278.
6. Asbury AC, Schultz KT, Klesius PH, Foster GW, Washburn SM: Factors affecting phagocytosis of bacteria by neutrophils in the mare's uterus. J Reprod Fertil Suppl 1982; 32: 151-159.
7. Nikolakopoulos E, Watson ED: Does artificial insemination with chilled, extended semen reduce the antigenic challenge to the mare's uterus compared with natural service? Theriogenology 1997; 47: 583-590.
8. Wingfield Digby NJ, Ricketts SW: Results of concurrent bacteriological and cytological examinations of the endometrium of mares in routine stud farm practice 1978-1981. J Reprod Fertil Suppl 1982; 32: 181-185.
9. Mann GE: Hormone control of prostaglandin F (2 alpha) production and oxytocin receptor concentrations in bovine endometrium in explant culture. Domest Anim Endocrinol 2001; 20: 217-226.
10. Herath S, Fischer DP, Werling D, Williams EJ, Lilly ST, Dobson H, Bryant CE, Sheldon IM: Expression and function of Toll-like receptor 4 in the endometrial cells of the uterus. Endocrinology 2006; 147: 562-570. Expression and function of Toll-like receptor 4 in the endometrial cells of the uterus
11. Leung S, Cheng Z, Sheldrick EL, Derecka K, Flint AP, Wathes DC: The effects of lipopolysaccharide and interleukins-1a, -2 and -6 on oxytocin receptor expression and prostaglandin production in bovine endometrium. J Endocrinol 2001; 168: 497-508.
12. Cheng Z, Elmes M, Kirkup S, Chin E, Abayasekara D, Wathes D: The effect of a diet supplemented with the n-6 polyunsaturated fatty acid linoleic acid on prostaglandin production in early and late-pregnant ewes. J Endocrinol 2005; 184: 165-178.
13. Berglund LA, Sharp DC, Vernon MW, Thatcher WW: Effect of pregnancy and collection technique on prostaglandin F in the uterine lumen of Pony mares. J Reprod Fertil Suppl 1982; 32: 335-341.
14. Vernon MW, Zavy M, Asquith RL, Sharp DC: Prostaglandin F2a in the equine endometrium: Steroid modulation and production capacities during estrous cycle and early pregnancy. Biol Reprod 1981; 25: 581-589.
15. Watson ED, Aubrey ES, Zanecosky HG, Sertich PL: Isolation and culture of glandular epithelial and stromal cells from the endometrium of mares. J Reprod Fertil 1992; 95: 269-275.
16. Watson ED: Release of immunoreactive arachidonate metabolites by equine endometrium in vitro. Am J Vet Res 1989; 50: 1207-1209.
17. Watson ED, Stokes CR, David JS, Bourne FJ, Ricketts SW: Concentrations of uterine luminal prostaglandins in mares with acute and persistent endometritis. Equine Vet J 1987; 19: 31-37.
18. Evans MJ, Hamer JM, Gason LM, Graham C, Asbury AC, Irvine CHG: Clearance of bacteria and non-antigenic markers following intra-uterine inoculation into maiden mares: Effect of steroid hormone environment. Theriogenology 1986; 26: 37-50.
19. Evans MJ, Hamer JM, Gason LM, Irvine CH: Factors affecting uterine clearance of inoculated materials in mares. J Reprod Fertil Suppl 1987; 35: 327-334.
20. Washburn SM, Klesius PH, Ganjam VK, Brown BG: Effect of estrogen and progesterone on the phagocytic response of ovariectomized mares infected in utero with beta-hemolytic streptococci. Am J Vet Res 1982; 43: 1367-1370.
21. Goody P: Horse Anatomy. London, J.A: Allen and Company Limited, 1983.
22. Pycock JFP Mare scanning: prediction of ovulation. UK Vet 2004; 9: 13-18.
23. LeBlanc M: The Mare. In Equine Stud Farm Medicine and Surgery, D Knottenbelt, M LeBlanc, C Lopate, R Pascoe (eds). Edinburgh, Elsevier Science Limited, 2003, pp 113-211.
24. McKinnon A, Squires E, Voss J: Ultrasonic evaluation of the mare's reproductive tract-part 1. Compend Contin Educ Pract Vet 1987; 9: 336-344.
25. Plotka ED, Witherspoon DM, Foley CW: Luteal function in the mare as reflected by progesterone concentrations in peripheral blood plasma. Am J Vet Res 1972; 33: 917-920.
26. Ginther OJ, Utt MD, Bergfelt DR, Beg MA: Controlling interelationships of progesterone/LH and estradiol/LH in mares. Anim Reprod Sci 2006; 95: 144-150.
27. Kenney RM: Cyclic and pathologic changes of the mare endometrium as detected by biopsy, with a note on early embryonic death. J Am Vet Med Assoc 1978; 172: 241-262.
28. Vandeplassche M, Henry M, Coryn M: The mature mid-cycle follicle in the mare. J Reprod Fertil Suppl 1979; 27: 157-162.
29. Janeway CJ, Medzhitov R: Innate immune recognition. Annu Rev Immunol 2002; 20: 197-216.
30. Watson ED: Uterine defence mechanisms in mares resistant and susceptible to persistent endometritis: A review. Equine Vet J 1988; 20: 397-400.
31. Cheng Z, Robinson R, Pushpakumara P, Mansbridge R, Wathes DC: Effect of dietary polyunsaturated fatty acids on uterine prostaglandin synthesis in the cow. J Endocrinol 2001; 171: 463-473.
32. Vagnoni KE, Abbruzzese SB, Christiansen ND, Holyoak GR: The influence of the phase of the estrous cycle on sheep endometrial tissue response to lipopolysaccharide. J Anim Sci 2001; 79: 463-469.
33. Lewis GS: Steroidal regulation of uterine immune defenses. Anim Reprod Sci 2004; 82-83: 281-294.
34. Lewis GS: Role of ovarian progesterone and potential role of prostaglandin F2alpha and prostaglandin E2 in modulating the uterine response to infectious bacteria in postpartum ewes. J Anim Sci 2003; 81: 285-293.
35. Sharp D, Zavy M, Vernon M, Bazer W, Thatcher W, Berglund L: The role of prostaglandins in the maternal recognition of pregnancy in mares. Anim Reprod Sci 1984; 7: 269-282.
36. Ferreira-Dias G, Bravo PP, Mateus L, Redmer DA, Medeiros JA: Microvascularization and angiogenic activity of equine corpora lutea throughout the estrous cycle. Domest Anim Endocrinol 2006; 30: 247-259.
37. Adams GP, Kastelic JP, Bergfelt DR, Ginther OJ: Effect of uterine inflammation and ultrasonically-detected uterine pathology on fertility in the mare. J Reprod Fertil Suppl 1987; 35: 445-454.
38. Pycock JF, Allen WE: Inflammatory components in uterine fluid from mares with experimentally induced bacterial endometritis. Equine Vet J 1990; 22: 422-425.
39. Arosh JA, Parent J, Chapdelaine P, Sirois J, Fortier MA: Expression of cyclooxygenases 1 and 2 and prostaglandin E synthase in bovine endometrial tissue during the estrous cycle. Biol Reprod 2002; 67: 161-169.
40. Roberto da Costa R, Ferreira-Dias G, Mateus L, Korzekwa A, Andronowska A, Platek R, Skarzynski D: Endometrial nitric oxide production and nitric oxide synthases in the equine endometrium: Relationship with microvascular density during the estrous cycle. Domest Anim Endocrinol 2006; 32: 287-302.
41. Fumuso E, Giguere S, Wade J, Rogan D, Videla-Dorna I, Bowden RA: Endometrial IL-1beta, IL-6 and TNF-alpha, mRNA expression in mares resistant or susceptible to post-breeding endometritis. Effects of estrous cycle, artificial insemination and immunomodulation. Vet Immunol Immunopathol 2003; 96: 31-41.
42. Kotilainen T, Huhtinen M, Katila T: Sperm-induced leukocytosis in the equine uterus. Theriogenology 1994; 41: 629-636.
43. Alghamdi A, Foster D, Troedsson M: Equine seminal plasma reduces sperm binding to polymorphonuclear neutrophils (PMNs) and improves the fertility of fresh semen inseminatated into inflamed uteri. Soc Reprod Fertil 2004; 127: 593-600.