Endometrial IL-1β, IL-6 and TNF-α, mRNA expression in mares resistant or susceptible to post-breeding endometritis: Effects of estrous cycle, artificial insemination and immunomodulation

Veterinary Immunology and Immunopathology

Volumn 96, Issue 1-2, 2003, Pages 31-41

  Fumuso, Elida ^a   Giguère, Steeve ^b   Wade, José ^c   Rogan, Dragan ^c   Videla Dorna, Ignacio ^a   Bowden, Raúl A ^a  

^a UNIVERSIDAD NACIONAL DEL CENTRO DE LA PROVINCIA DE BUENOS AIRES   (Argentina)

^b University of Florida College of Veterinary Medicine   (United States)

^c Clonee Co   (Ireland)

Author keywords

Breeding; Endometritis; Immunomodulation; Mares; PCR; Reproduction

Indexed keywords

IMMUNOMODULATING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL INSEMINATION; BACTERIAL CELL; BREEDING; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIESTRUS; DISEASE PREDISPOSITION; ENDOMETRITIS; ENDOMETRIUM; ENDOMETRIUM BIOPSY; ESTRUS; ESTRUS CYCLE; FEMALE; HORSE; IMMUNOMODULATION; INFECTION RESISTANCE; MYCOBACTERIUM PHLEI; NONHUMAN; PROTEIN EXPRESSION; TISSUE LEVEL;

MYCOBACTERIUM; MYCOBACTERIUM PHLEI;

EID: 0141651800     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2427(03)00137-5     Document Type: Article

References (35)

1. Alghamdi A., Troedsson M.H.T., Laschkewitsch T., Xue J.L. Uterine secretion from mares with post-breeding endometritis alters sperm motion characteristics in vitro. Theriogenology. 55:2001;1019-1028.
2. Barañao R. Citoquinas en el proceso reproductivo. Reproducción (Argentina). 1:1997;13-27.
3. Cadario M., Thatcher W., Klapstein E., Merrit A., Archbald L., Thatcher M., LeBlanc M. Dynamics of prostaglandin secretion, intrauterine fluid and uterine clearance in reproductively normal mares and mares with delayed uterine clearance. Theriogenology. 52:1999;1181-1192.
4. Cadario M., Losinno L., Giguère S., Aguilar J., Jack T., Macpherson M., Fitzpatrick C., Uhl E. Uterine expression of fibrogenic cytokines in the mare. Theriogenology. 58:2002;449-452.
5. Dinarello, C., 1992. The biology of interleukin-1. In: Kishimoto, T. (Ed.), Interleukins: Molecular Biology and Immunobiology, Chemistry of Immunology, vol. 51. Karger Verlag, Basel, pp. 1-32.
6. Erkinheimo T., Saukkonen K., Narko K., Jalkanen J., Ylikorkala O., Ristimaki A. J. Clin. Endoc. Metab. 85:2000;3468-3475.
7. Fumuso, E.A., González, C., Videla Dorna, I., Inchausti, E., Tallarico, M., Berestin, V., Wade, J., Aguilar, J., Losinno, L., Soto, P., Bowden, R.A., 2000. Effect of an immunomodulator in mares resistant and susceptible to endometritis. In: Proceedings of the Second International Conference on Experimental and Clinical Reproduction Immunobiology, 15-18 November. Elsevier, Amsterdam, The Netherlands, p. 104.
8. Garton N.J., Gilleron M., Brando T., Dan H.H., Giguère S., Puzo G., Prescott J.F., Sutcliffe I.C. A novel lipoarabinomannan from the equine pathogen Rhodococcus equi: structure and effect on macrophage cytokine production. J. Biol. Chem. 177:2002;31722-31733.
9. Hunt J., Chen H., Hu X., Talibzadeh S. Tumor necrosis factor α mRNA and protein in human endometrium. Biol. Reprod. 47:1992;141-147.
10. Kaplanski G., Marin V., Montero-Julian F., Mantovani A., Franarier C. IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation. Trends Immunol. 24:2003;25-29.
11. Katila T. Onset and duration of uterine inflammatory response of mares after insemination with fresh semen. Biol. Repod. Mono. 1:1995;515-517.
12. Kauma S., Matt D., Strom S., Eirman D., Tuner T. Interleukin 1β IL-1β, HLA-DR β in endometrium, placenta and placental membranes. Am. J. Obstet. Gynecol. 163:1990;1430-1436.
13. Kenney, R., Doig, P., 1986. Equine endometrial biopsy. In: Morrow, D. (Ed.), Current Therapy in Theriogenology, vol. 2. WB Saunders, Philadelphia, pp. 723-729.
14. Kotilainen T., Huhtinen M., Katila T. Sperm-induced leukocytosis in the equine uterus. Theriogenology. 16:1994;630-631.
15. Leung S., Cheng Z., Sheldrick E., Derecks K., Flint A., Wathes D. The effects of lipopolysaccharide and interleukins-1α, -2 and -6 on oxytocin receptor expression and prostaglandin production in bovine endometrium. J. Endocrinol. 168:2001;497-508.
16. Leutenegger C.M., von Rechenberg B., Huder J.B., Zlinsky K., Mislin C., Akens M.K., Auer J., Lutz H. Quantitative real-time PCR for equine cytokine mRNA in nondecalcified bone tissue embedded in methyl methacrylate. Calcif. Tissue Int. 65:1999;378-383.
17. Losinno L., Woods G., Miragaya M. Uterine and oviductal inflammation in anovulatory mares with ultrasonographycally detected intrauterine luminal fluid. Theriogenology. 48:1997;1361-1368.
18. MacKay, R., 2000. Inflammation. In: Lunn, P., Horohov, D. (Eds.). Vet. Clin. North Am. Equine Pract.: Immunol. 16, 15-27.
19. McKinnon A., Squires E., Harrison B., Blach E., Shideler R. Ultarasonographic studies on the reproductive tract of mares after parturition. Effect of involution and uterine fluid on pregnancy rates in mares with normal and delayed first postpartum ovulatory cycles. J. Am. Vet. Med. Assoc. 192:1988;350-353.
20. Murtaugh, M., Myers, M., 1995. Future directions in animal cytokine research and applications. In: Myers, M., Murtaugh, M. (Eds.), Cytokines in Animal Health and Diseases. Book News Inc., Portland, OR, pp. 449-457.
21. Nikolakopoulos E., Watson E.D. Uterine contractility is necessary for the clearance of intrauterine fluid but not bacteria after bacterial infusion in the mare. Theriogenology. 52:1999;413-423.
22. Semer D., Reisler K., MacDonald P., Casey M. Responsiveness of human endometrial stromal cells to cytokines. Ann. N. Y. Acad. Sci. 622:1991;99-110.
23. Simon C., Piquette G., Frances A., El-Danasouri I., Irwin J. The effect of interleukin-IP (IL-1β) on the regulation of IL1 receptor type messanger ribonucleic acid and protein levels in cultured human endometrial stromal and glandular cells. J. Clin. Endocrinol. Metab. 78:1994;675-681. Summerfield N., Watson E. Endometrial macrophage populations in genitally normal mares at oestrus and dioestrus and in mares susceptible to endometritis. Equine Vet. J. 30:1998;79-81.
24. Summerfield N., Watson E. Endometrial macrophage populations in genitally normal mares at oestrus and dioestrus and in mares susceptible to endometritis. Equine Vet. J. 30:1998;79-81.
25. Takacs L., Kavacs E., Smith M., Young H., Durun S. Detection of IL-1β gene expression by in situ hybridization tissue localization of IL-1 mRNA in the normal C57BL/6 mouse. J. Immunol. 141:1988;3081-3087.
26. Troedsson M.H.T. Comparative treatment of mares susceptible to chronic uterine infection. Am. J. Vet. Res. 56:1995;468-472.
27. Troedsson M.H.T. Therapeutic considerations for mating-induced endometritis. Pferdeheilkunde. 13:1997;516-520.
28. Troedsson M.H.T. Uterine clearence and resistance to persistent endometritis in the mare. Theriogenology. 52:1999;461-471.
29. Troedsson M.H.T., Loset K., Alghamdi A.M., Dahms B., Crabo B.G. Interaction between equine semen and the endometrium: the inflammatory response to semen. Anim. Reprod. Sci. 68:2001;273-278.
30. Underhill D., Ozinnsky K., Smith K., Aderem A. Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages. Proc. Natl. Acad. Sci. U.S.A. 96:1999;14459-14463.
31. Vásquez-López M., Maffrand C., Losinno L., Maldonado J. Rev. Col. Cienc. Pec. 13(S):2000;33.
32. Wade J. Interacción entre la reproducción y el sistema inmunológico. Sus implicaciones en la investigación y el manejo reproductivo. Rev. Arg. Prod. Anim. 15:1995;151-158. Watson, E., 2000. Post-breeding endometritis in the mare. In: Proceedings of the 14th International Congress on Animal Reproduction, 2-6 July 2000. Elsevier, Stockholm, pp. 221-232.
33. Watson, E., 2000. Post-breeding endometritis in the mare. In: Proceedings of the 14th International Congress on Animal Reproduction, 2-6 July 2000. Elsevier, Stockholm, pp. 221-232.
34. Wu Y., Khan Shaghaghi E., Jacquot C., Pallardy M., Gardier A.M. Synergism between interleukin-6 and interleukin-1β in hypothalamic serotonin release: a reverse in vivo microdialysis study in F344 rats. Eur. Cytokine Network. 10:1999;57-64.
35. Yelavarthi K.K., Fishback J.L., Hunt J.S. Analysis of HLA-G mRNA in human placental and extraplacental membrane cells by in situ hybridization. J. Immunol. 146:1991;2847-2854.