Expansion of Foxp3-expressing regulatory T cells in vitro by dendritic cells modified with polymeric particles carrying a plasmid encoding interleukin-10

Biomaterials

Volumn 29, Issue 9, 2008, Pages 1250-1261

  Jia, Liang ^a   Kovacs, Jeffrey R ^a   Zheng, Ying ^a   Shen, Hongmei ^b   Gawalt, Ellen S ^a   Meng, Wilson S ^a  

^a DUQUESNE UNIVERSITY   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Dendritic cells; Foxp3; Interleukin 10; Non viral gene delivery; PLGA; Regulatory T cells

Indexed keywords

DNA; GENE ENCODING; IMMUNOLOGY; ORGANIC ACIDS; TRANSCRIPTION FACTORS;

DENDRITIC CELLS; GENE DELIVERY; GENE THERAPY; IMMUNOSUPPRESSIVE CYTOKINES; PLASMID ENCODING;

CELLS;

ALLOANTIGEN; AUTOANTIGEN; CATION; CYTOKINE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 10; POLYGLACTIN; POLYMER; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; BONE MARROW; COLLOID; COMPLEX FORMATION; CONTROLLED STUDY; DENDRITIC CELL; DOWN REGULATION; FEMALE; GENE; GENE TARGETING; IL 10 GENE; IMMUNE RESPONSE; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BASE SEQUENCE; BIOCOMPATIBLE MATERIALS; DENDRITIC CELLS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; INTERLEUKIN-10; LACTIC ACID; LYMPHOCYTE CULTURE TEST, MIXED; MATERIALS TESTING; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PARTICLE SIZE; PLASMIDS; POLYGLYCOLIC ACID; POLYMERS; RECOMBINANT PROTEINS; T-LYMPHOCYTES, REGULATORY; UP-REGULATION;

EID: 38349074133     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2007.11.015     Document Type: Article

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