-
1
-
-
0033230342
-
A modified AIDA protocol with anthracycline-based consolidation results in high antileukemic efficacy and reduced toxicity in newly diagnosed PML/RARalpha-positive acute promyelocytic leukemia. PETHEMA group
-
Sanz MA et al., A modified AIDA protocol with anthracycline-based consolidation results in high antileukemic efficacy and reduced toxicity in newly diagnosed PML/RARalpha-positive acute promyelocytic leukemia. PETHEMA group. Blood, 1999. 94 (9): P. 3015-3021
-
(1999)
Blood
, vol.94
, Issue.9
, pp. 3015-3021
-
-
Sanz, M.A.1
-
2
-
-
0032480930
-
Chemotherapy compared with autologous or allogeneic bone marrow transplantation in the management of acute myeloid leukemia in first remission
-
Cassileth PA et al., Chemotherapy compared with autologous or allogeneic bone marrow transplantation in the management of acute myeloid leukemia in first remission. N Engl J Med, 1998. 339 (23): P. 1649-1656
-
(1998)
N Engl J Med
, vol.339
, Issue.23
, pp. 1649-1656
-
-
Cassileth, P.A.1
-
3
-
-
9144238671
-
A phase 3 study of three induction regimens and of priming with GM-CSF in older adults with acute myeloid leukemia: A trial by the Eastern Cooperative Oncology Group
-
Rowe JM et al., A phase 3 study of three induction regimens and of priming with GM-CSF in older adults with acute myeloid leukemia: A trial by the Eastern Cooperative Oncology Group. Blood, 2004. 103 (2): P. 479-485
-
(2004)
Blood
, vol.103
, Issue.2
, pp. 479-485
-
-
Rowe, J.M.1
-
4
-
-
0034672269
-
Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: A Southwest Oncology Group/ Eastern Cooperative Oncology Group Study
-
Slovak ML et al., Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: A Southwest Oncology Group/Eastern Cooperative Oncology Group Study. Blood, 2000. 96 (13): P. 4075-4083
-
(2000)
Blood
, vol.96
, Issue.13
, pp. 4075-4083
-
-
Slovak, M.L.1
-
5
-
-
0030451722
-
Internal tandem duplication of the flt3 gene found in acute myeloid leukemia
-
Nakao M et al., Internal tandem duplication of the flt3 gene found in acute myeloid leukemia. Leukemia, 1996. 10(12): P. 1911-1918
-
(1996)
Leukemia
, vol.10
, Issue.12
, pp. 1911-1918
-
-
Nakao, M.1
-
6
-
-
0023242257
-
Expression of normal and mutant ras proteins in human acute leukemia
-
Shen WP et al., Expression of normal and mutant ras proteins in human acute leukemia. Oncogene, 1987, 1(2): P. 157-165
-
(1987)
Oncogene
, vol.1
, Issue.2
, pp. 157-165
-
-
Shen, W.P.1
-
7
-
-
0035871889
-
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
-
Yamamoto Y et al., Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies. Blood, 2001. 97 (8): P. 2434-2439
-
(2001)
Blood
, vol.97
, Issue.8
, pp. 2434-2439
-
-
Yamamoto, Y.1
-
8
-
-
0035886024
-
Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
-
Guzman ML et al., Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood, 2001. 98 (8): p. 2301-2307
-
(2001)
Blood
, vol.98
, Issue.8
, pp. 2301-2307
-
-
Guzman, M.L.1
-
9
-
-
0037059012
-
Preferential induction of apoptosis for primary human leukemic stem cells
-
Guzman ML et al., Preferential induction of apoptosis for primary human leukemic stem cells. PNAS, 2002. 99 (25): P. 16220-16225
-
(2002)
PNAS
, vol.99
, Issue.25
, pp. 16220-16225
-
-
Guzman, M.L.1
-
10
-
-
4344653856
-
Constitutive activation of PI3K is involved in the spontaneous proliferation of primary acute myeloid leukemia cells: Direct evidence of PI3K activation
-
Kubota Y et al., Constitutive activation of PI3K is involved in the spontaneous proliferation of primary acute myeloid leukemia cells: direct evidence of PI3K activation. Leukemia, 2004. 18 (8): P. 1438-1440
-
(2004)
Leukemia
, vol.18
, Issue.8
, pp. 1438-1440
-
-
Kubota, Y.1
-
11
-
-
1242285048
-
Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias
-
Zhao S et al., Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias. Leukemia, 2004. 18 (2): P. 267-275
-
(2004)
Leukemia
, vol.18
, Issue.2
, pp. 267-275
-
-
Zhao, S.1
-
12
-
-
0042744837
-
Survival of acute myeloid leukemia cells requires PI3 kinase activation
-
Xu Q et al., Survival of acute myeloid leukemia cells requires PI3 kinase activation. Blood, 2003. 102 (3): P. 972-980
-
(2003)
Blood
, vol.102
, Issue.3
, pp. 972-980
-
-
Xu, Q.1
-
13
-
-
17144387901
-
PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways
-
Grandage VL et al., PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways. Leukemia, 2005. 19 (4): P. 586-594
-
(2005)
Leukemia
, vol.19
, Issue.4
, pp. 586-594
-
-
Grandage, V.L.1
-
14
-
-
28844480101
-
mTOR regulates cell survival after etoposide treatment in primary AML cells
-
Xu Q, JE Thompson, M Carroll, mTOR regulates cell survival after etoposide treatment in primary AML cells. Blood, 2005. 106 (13): P. 4261-4268
-
(2005)
Blood
, vol.106
, Issue.13
, pp. 4261-4268
-
-
Xu, Q.1
Thompson, J.E.2
Carroll, M.3
-
15
-
-
0034823632
-
Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia
-
Milella M et al., Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia. J Clin Invest, 2001. 108 (6): P. 851-859
-
(2001)
J Clin Invest
, vol.108
, Issue.6
, pp. 851-859
-
-
Milella, M.1
-
17
-
-
12844268111
-
Imatinib paradigm or anomaly?
-
Druker BJ, Imatinib: Paradigm or anomalyP Cell Cycle, 2004. 3 (7): p. 833-835
-
(2004)
Cell Cycle
, vol.3
, Issue.7
, pp. 833-835
-
-
Druker, B.J.1
-
18
-
-
0033987746
-
Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia
-
Druker BJ, NB Lydon, Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia. J Clin Invest, 2000. 105 (1): P. 3-7 3-7
-
(2000)
J Clin Invest,
, vol.105
, Issue.1
, pp. 3-7
-
-
Druker, B.J.1
Lydon, N.B.2
-
19
-
-
0036720398
-
The roles of FLT3 in hematopoiesis and leukemia
-
Gilliland DG, JD Griffin, The roles of FLT3 in hematopoiesis and leukemia. Blood, 2002. 100 (5): P. 1532-1542
-
(2002)
Blood
, vol.100
, Issue.5
, pp. 1532-1542
-
-
Gilliland, D.G.1
Griffin, J.D.2
-
20
-
-
1842430924
-
Small molecule FLT3 tyrosine kinase inhibitors
-
Levis M, D Small, Small molecule FLT3 tyrosine kinase inhibitors. Curr Pharm Des, 2004. 10 (11): P. 1183-1193
-
(2004)
Curr Pharm Des
, vol.10
, Issue.11
, pp. 1183-1193
-
-
Levis, M.1
Small, D.2
-
21
-
-
19944427559
-
Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412
-
Stone RM et al., Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412. Blood, 2005. 105 (1): P. 54-60
-
(2005)
Blood
, vol.105
, Issue.1
, pp. 54-60
-
-
Stone, R.M.1
-
22
-
-
33845240584
-
Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: Safety, pharmacokinetics, and pharmacodynamics
-
DeAngelo DJ et al., Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: Safety, pharmacokinetics, and pharmacodynamics. Blood, 2006. 108 (12): P. 3674-3681
-
(2006)
Blood
, vol.108
, Issue.12
, pp. 3674-3681
-
-
DeAngelo, D.J.1
-
23
-
-
1842420032
-
Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia
-
Smith BD et al., Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia. Blood, 2004. 103 (10): P. 3669-3676
-
(2004)
Blood
, vol.103
, Issue.10
, pp. 3669-3676
-
-
Smith, B.D.1
-
24
-
-
19944431093
-
A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease
-
Fiedler W, et al., A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease. Blood, 2005. 105 (3): P. 986-993
-
(2005)
Blood
, vol.105
, Issue.3
, pp. 986-993
-
-
Fiedler, W.1
-
25
-
-
32244447213
-
The role of tuberin in cellular differentiation: Are B-Raf and MAPK involved?
-
Karbowniczek M, EP Henske, The role of tuberin in cellular differentiation: Are B-Raf and MAPK involved? Ann N Y Acad Sci 2005. 1059: P. 168-173
-
(2005)
Ann N Y Acad Sci
, vol.1059
, pp. 168-173
-
-
Karbowniczek, M.1
Henske, E.P.2
-
26
-
-
38349013981
-
Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways
-
Piloto O, et al.: Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways. Blood 2006
-
(2006)
Blood
-
-
Piloto, O.1
-
27
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME et al., Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science, 2001. 293 (5531): P. 876-880
-
(2001)
Science
, vol.293
, Issue.5531
, pp. 876-880
-
-
Gorre, M.E.1
-
28
-
-
30144432781
-
Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain
-
Heidel F et al., Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain. Blood, 2006. 107 (1): P. 293-300
-
(2006)
Blood
, vol.107
, Issue.1
, pp. 293-300
-
-
Heidel, F.1
-
29
-
-
33751170444
-
Plasma inhibitory activity (PIA): A pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors
-
Levis M et al., Plasma inhibitory activity (PIA): A pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors. Blood, 2006. 108 (10): P. 3477-3483
-
(2006)
Blood
, vol.108
, Issue.10
, pp. 3477-3483
-
-
Levis, M.1
-
30
-
-
34249829699
-
Phase IB study of PKC412, an oral FLT3 kinase inhibitor, in sequential and simultaneous combinations with daunorubicin and cytarabine (da) induction and high-dose cytarabine consolidation in newly diagnosed adult patients (pts) with acute myeloid leukemia (AML) under age 61
-
Stone RM et al., Phase IB study of PKC412, an oral FLT3 kinase inhibitor, in sequential and simultaneous combinations with daunorubicin and cytarabine (da) induction and high-dose cytarabine consolidation in newly diagnosed adult patients (pts) with acute myeloid leukemia (AML) under age 61. Blood (ASH Annual Meeting Abstracts), 2006. 108 (11): P. 157
-
(2006)
Blood (ASH Annual Meeting Abstracts)
, vol.108
, Issue.11
, pp. 157
-
-
Stone, R.M.1
-
31
-
-
38849174002
-
Phase 1/2 study of tandutinib (MLN518) plus standard induction chemotherapy in newly diagnosed acute myelogenous leukemia (AML)
-
DeAngelo DJ, et al.: Phase 1/2 study of tandutinib (MLN518) plus standard induction chemotherapy in newly diagnosed acute myelogenous leukemia (AML). Blood (ASH Annual Meeting Abstracts) 2006, 108(11): 158
-
(2006)
Blood (ASH Annual Meeting Abstracts)
, vol.108
, Issue.11
, pp. 158
-
-
DeAngelo, D.J.1
-
32
-
-
33747105356
-
A randomized, open-label study of lestaurtinib (CEP-701), an oral FLT3 inhibitor, administered in sequence with chemotherapy in patients with relapsed AML harboring FLT3 activating mutations: Clinical response correlates with successful FLT3 inhibition
-
Levis M et al., A randomized, open-label study of lestaurtinib (CEP-701), an oral FLT3 inhibitor, administered in sequence with chemotherapy in patients with relapsed AML harboring FLT3 activating mutations: Clinical response correlates with successful FLT3 inhibition. Blood, 2005. 106 (11): P. 121a
-
(2005)
Blood
, vol.106
, Issue.11
-
-
Levis, M.1
-
33
-
-
0035383789
-
Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: A phase 1 clinical-laboratory correlative trial
-
Karp JE et al., Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: A phase 1 clinical-laboratory correlative trial. Blood, 2001. 97 (11): P. 3361-3369
-
(2001)
Blood
, vol.97
, Issue.11
, pp. 3361-3369
-
-
Karp, J.E.1
-
34
-
-
34250006852
-
A phase 2 study of the oral farnesyltransferase inhibitor tipifarnib in patients with refractory or relapsed acute myeloid leukemia
-
Harousseau JL et al., A phase 2 study of the oral farnesyltransferase inhibitor tipifarnib in patients with refractory or relapsed acute myeloid leukemia. Blood, 2007. 109 (12): P. 5151-5156
-
(2007)
Blood
, vol.109
, Issue.12
, pp. 5151-5156
-
-
Harousseau, J.L.1
-
35
-
-
33847001315
-
A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia
-
Lancet JE et al., A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia. Blood, 2007. 109 (4): P. 1387-1394
-
(2007)
Blood
, vol.109
, Issue.4
, pp. 1387-1394
-
-
Lancet, J.E.1
-
36
-
-
34248363673
-
A multicenter phase 2 study of the farnesyltransferase inhibitor tipifarnib in intermediate- to high-risk myelodysplastic syndrome
-
Fenaux P et al., A multicenter phase 2 study of the farnesyltransferase inhibitor tipifarnib in intermediate- to high-risk myelodysplastic syndrome. Blood, 2007. 109 (10): P. 4158-4163
-
(2007)
Blood
, vol.109
, Issue.10
, pp. 4158-4163
-
-
Fenaux, P.1
-
37
-
-
20444416005
-
Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells
-
Zhu K et al., Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells. Blood, 2005. 105 (12): P. 4759-4766
-
(2005)
Blood
, vol.105
, Issue.12
, pp. 4759-4766
-
-
Zhu, K.1
-
38
-
-
34547668530
-
Enhancement of the antitumor activity of tamoxifen and anastrozole by the farnesyltransferase inhibitor lonafarnib (SCH66336)
-
Liu G et al., Enhancement of the antitumor activity of tamoxifen and anastrozole by the farnesyltransferase inhibitor lonafarnib (SCH66336). Anticancer Drugs, 2007. 18 (8): P. 923-931
-
(2007)
Anticancer Drugs
, vol.18
, Issue.8
, pp. 923-931
-
-
Liu, G.1
-
39
-
-
34250735732
-
Active oral regimen for elderly adults with newly diagnosed acute myelogenous leukemia (AML): Hase I trial of oral tipifarnib (T) combined with oral etoposide (E) for adults ≥ 70 who are not candidates for traditional cytotoxic chemotherapy (TCC)
-
Karp JE, et al.: Active oral regimen for elderly adults with newly diagnosed acute myelogenous leukemia (AML): Phase I trial of oral tipifarnib (T) combined with oral etoposide (E) for adults ≥ 70 who are not candidates for traditional cytotoxic chemotherapy (TCC). ASH Annual Meeting Abstracts 2006, 108(11): 426
-
(2006)
ASH Annual Meeting Abstracts
, vol.108
, Issue.11
, pp. 426
-
-
Karp, J.E.1
-
40
-
-
20144363954
-
Antileukemic activity of rapamycin in acute myeloid leukemia
-
Recher C et al., Antileukemic activity of rapamycin in acute myeloid leukemia. Blood, 2005. 105 (6): P. 2527-2534
-
(2005)
Blood
, vol.105
, Issue.6
, pp. 2527-2534
-
-
Recher, C.1
-
41
-
-
33749002279
-
Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies
-
Yee KW et al., Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies. Clin Cancer Res, 2006. 12 (17): P. 5165-5173
-
(2006)
Clin Cancer Res
, vol.12
, Issue.17
, pp. 5165-5173
-
-
Yee, K.W.1
-
42
-
-
27644445192
-
A Phase II Study of Temsirolimus (CCI-779) in Patients with Advanced Leukemias
-
Yee KWL et al., A Phase II Study of Temsirolimus (CCI-779) in Patients with Advanced Leukemias. Blood (ASH Annual Meeting Abstracts), 2004. 104 (11): P. 4523a
-
(2004)
Blood (ASH Annual Meeting Abstracts)
, vol.104
, Issue.11
-
-
Yee, K.W.L.1
-
43
-
-
34047145812
-
Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML
-
Zeng Z, et al.: Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML. Blood 2006
-
(2006)
Blood
-
-
Zeng, Z.1
-
44
-
-
38349044552
-
A phase I dose escalation study of the mTOR inhibitor sirolimus and MEC chemotherapy targeting signal transduction in leukemic stem cells for acute myeloid leukemia
-
Luger S, et al.: A phase I dose escalation study of the mTOR inhibitor sirolimus and MEC chemotherapy targeting signal transduction in leukemic stem cells for acute myeloid leukemia. ASH Annual Meeting Abstracts 2006, 108(11): 161
-
(2006)
ASH Annual Meeting Abstracts
, vol.108
, Issue.11
, pp. 161
-
-
Luger, S.1
-
45
-
-
34249340637
-
Chromosome aberrations, gene mutations and expression changes, and prognosis in adult acute myeloid leukemia
-
Mrozek K, Bloomfield CD: Chromosome aberrations, gene mutations and expression changes, and prognosis in adult acute myeloid leukemia. Hematology (Am Soc Hematol Educ Program) 2006:169-177
-
(2006)
Hematology (Am Soc Hematol Educ Program)
, pp. 169-177
-
-
Mrozek, K.1
Bloomfield, C.D.2
-
46
-
-
33748467435
-
Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): A Cancer and Leukemia Group B Study
-
Paschka P et al., Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): A Cancer and Leukemia Group B Study. J Clin Oncol, 2006. 24 (24): P. 3904-3911
-
(2006)
J Clin Oncol
, vol.24
, Issue.24
, pp. 3904-3911
-
-
Paschka, P.1
-
47
-
-
2342518106
-
Efficacy and safety of imatinib in adult patients with c-kit-positive acute myeloid leukemia
-
Kindler T et al., Efficacy and safety of imatinib in adult patients with c-kit-positive acute myeloid leukemia. Blood, 2004. 103 (10): P. 3644-3654
-
(2004)
Blood
, vol.103
, Issue.10
, pp. 3644-3654
-
-
Kindler, T.1
-
48
-
-
0037606031
-
Sustained complete hematologic remission after administration of the tyrosine kinase inhibitor imatinib mesylate in a patient with refractory, secondary AML
-
Kindler T et al., Sustained complete hematologic remission after administration of the tyrosine kinase inhibitor imatinib mesylate in a patient with refractory, secondary AML. Blood, 2003. 101 (8): P. 2960-2962
-
(2003)
Blood
, vol.101
, Issue.8
, pp. 2960-2962
-
-
Kindler, T.1
-
49
-
-
10744229862
-
Results of imatinib mesylate therapy in patients with refractory or recurrent acute myeloid leukemia, high-risk myelodysplastic syndrome, and myeloproliferative disorders
-
Cortes J et al., Results of imatinib mesylate therapy in patients with refractory or recurrent acute myeloid leukemia, high-risk myelodysplastic syndrome, and myeloproliferative disorders. Cancer, 2003. 97 (11): P. 2760-2766
-
(2003)
Cancer
, vol.97
, Issue.11
, pp. 2760-2766
-
-
Cortes, J.1
-
50
-
-
0033485961
-
Cellular vascular endothelial growth factor is a predictor of outcome in patients with acute myeloid leukemia
-
Aguayo A et al., Cellular vascular endothelial growth factor is a predictor of outcome in patients with acute myeloid leukemia. Blood, 1999. 94 (11): P. 3717-3721
-
(1999)
Blood
, vol.94
, Issue.11
, pp. 3717-3721
-
-
Aguayo, A.1
-
51
-
-
0033957420
-
Evidence of increased angiogenesis in patients with acute myeloid leukemia
-
Hussong JW, GM Rodgers, PJ Shami, Evidence of increased angiogenesis in patients with acute myeloid leukemia. Blood, 2000. 95 (1): P. 309-313
-
(2000)
Blood
, vol.95
, Issue.1
, pp. 309-313
-
-
Hussong, J.W.1
Rodgers, G.M.2
Shami, P.J.3
-
52
-
-
33744482540
-
Phase 1 study of PTK787/ZK 222584, a small molecule tyrosine kinase receptor inhibitor, for the treatment of acute myeloid leukemia and myelodysplastic syndrome
-
Roboz GJ et al., Phase 1 study of PTK787/ZK 222584, a small molecule tyrosine kinase receptor inhibitor, for the treatment of acute myeloid leukemia and myelodysplastic syndrome. Leukemia, 2006. 20 (6): P. 952-957
-
(2006)
Leukemia
, vol.20
, Issue.6
, pp. 952-957
-
-
Roboz, G.J.1
-
53
-
-
2542547507
-
Targeting vascular endothelial growth factor for relapsed and refractory adult acute myelogenous leukemias: Therapy with sequential 1-beta- d -arabinofuranosylcytosine, mitoxantrone, and bevacizumab
-
Karp JE et al., Targeting vascular endothelial growth factor for relapsed and refractory adult acute myelogenous leukemias: Therapy with sequential 1-beta- d -arabinofuranosylcytosine, mitoxantrone, and bevacizumab. Clin Cancer Res, 2004. 10 (11): P. 3577-3585
-
(2004)
Clin Cancer Res
, vol.10
, Issue.11
, pp. 3577-3585
-
-
Karp, J.E.1
|