Detailed molecular characterization of cord blood-derived endothelial progenitors

Experimental Hematology

Volumn 36, Issue 2, 2008, Pages 193.e1-193.e15

  Igreja, Cátia ^a   Fragoso, Rita ^a   Caiado, Francisco ^a   Clode, Nuno ^b   Henriques, Alexandra ^b   Camargo, Lauren ^c   Reis, Eduardo M ^c   Dias, Sérgio ^a,d  

^a INSTITUTO PORTUGUÊS DE ONCOLOGIA DE LISBOA FRANCISCO GENTIL   (Portugal)

^b INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; CD34 ANTIGEN; COMPLEMENTARY DNA; UNTRANSLATED RNA;

ARTICLE; CELL DIFFERENTIATION; DNA MICROARRAY; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; UMBILICAL CORD BLOOD;

EID: 38349048497     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2007.09.001     Document Type: Article

References (58)

1. Asahara T., Masuda H., Takahashi T., et al. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 85 (1999) 221-228
2. Lyden D., Hattori K., Dias S., et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med 7 (2001) 1194-1201
3. Rafii S., Lyden D., Benezra R., Hattori K., and Heissig B. Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?. Nat Rev Cancer 2 (2002) 826-835
4. Rafii S., and Lyden D. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med 9 (2003) 702-712
5. Wijelath E.S., Rahman S., Murray J., Patel Y., Savidge G., and Sobel M. Fibronectin promotes VEGF-induced CD34 cell differentiation into endothelial cells. J Vasc Surg 39 (2004) 655-660
6. Wang C.H., Ciliberti N., Li S.H., et al. Rosiglitazone facilitates angiogenic progenitor cell differentiation toward endothelial lineage: a new paradigm in glitazone pleiotropy. Circulation 109 (2004) 1392-1400
7. Hildbrand P., Cirulli V., Prinsen R.C., et al. The role of angiopoietins in the development of endothelial cells from cord blood CD34+ progenitors. Blood 104 (2004) 2010-2019
8. Bruhl T., Heeschen C., Aicher A., et al. p21Cip1 levels differentially regulate turnover of mature endothelial cells, endothelial progenitor cells, and in vivo neovascularization. Circ Res 94 (2004) 686-692
9. Tepper O.M., Galiano R.D., Capla J.M., et al. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 106 (2002) 2781-2786
10. Schatteman G.C., Hanlon H.D., Jiao C., Dodds S.G., and Christy B.A. Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice. J Clin Invest 106 (2000) 571-578
11. Heeschen C., Lehmann R., Honold J., et al. Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease. Circulation 109 (2004) 1615-1622
12. Vasa M., Fichtlscherer S., Aicher A., et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 89 (2001) E1-E7
13. Chen J.Z., Zhang F.R., Tao Q.M., Wang X.X., and Zhu J.H. Number and activity of endothelial progenitor cells from peripheral blood in patients with hypercholesterolaemia. Clin Sci (Lond) 107 (2004) 273-280
14. Dimmeler S., and Vasa-Nicotera M. Aging of progenitor cells: limitation for regenerative capacity?. J Am Coll Cardiol 42 (2003) 2081-2082
15. Mattick J.S. RNA regulation: a new genetics?. Nat Rev Genet 5 (2004) 316-323
16. Mattick J.S., and Makunin I.V. Non-coding RNA. Hum Mol Genet 15 spec 1 (2006) R17-R29
17. Willingham A.T., and Gingeras T.R. TUF love for "junk" DNA. Cell 125 (2006) 1215-1220
18. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 (2004) 281-297
19. Kiss T. Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions. Cell 109 (2002) 145-148
20. Okazaki Y., Furuno M., Kasukawa T., et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature 420 (2002) 563-573
21. Yelin R., Dahary D., Sorek R., et al. Widespread occurrence of antisense transcription in the human genome. Nat Biotechnol 21 (2003) 379-386
22. Igreja C., Courinha M., Cachaco A.S., et al. Characterization and clinical relevance of circulating and biopsy-derived endothelial progenitor cells in lymphoma patients. Haematologica 92 (2007) 469-477
23. Louro R., Nakaya H.I., Amaral P.P., et al. Androgen responsive intronic non-coding RNAs. BMC Biol 5 (2007) 4
24. Tusher V.G., Tibshirani R., and Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 98 (2001) 5116-5121
25. Naoumova R.P., Bonney S.A., Eichenbaum-Voline S., et al. Confirmed locus on chromosome 11p and candidate loci on 6q and 8p for the triglyceride and cholesterol traits of combined hyperlipidemia. Arterioscler Thromb Vasc Biol 23 (2003) 2070-2077
26. Aouizerat B.E., Allayee H., Cantor R.M., et al. A genome scan for familial combined hyperlipidemia reveals evidence of linkage with a locus on chromosome 11. Am J Hum Genet 65 (1999) 397-412
27. Davies J.L., Kawaguchi Y., Bennett S.T., et al. A genome-wide search for human type 1 diabetes susceptibility genes. Nature 371 (1994) 130-136
28. Reed P., Cucca F., Jenkins S., et al. Evidence for a type 1 diabetes susceptibility locus (IDDM10) on human chromosome 10p11-q11. Hum Mol Genet 6 (1997) 1011-1016
29. Johnson G.C., Koeleman B.P., and Todd J.A. Limitations of stratifying sib-pair data in common disease linkage studies: an example using chromosome 10p14-10q11 in type 1 diabetes. Am J Med Genet 113 (2002) 158-166
30. Schonberger J., Levy H., Grunig E., et al. Dilated cardiomyopathy and sensorineural hearing loss: a heritable syndrome that maps to 6q23-24. Circulation 101 (2000) 1812-1818
31. Shaked Y., Bocci G., Munoz R., et al. Cellular and molecular surrogate markers to monitor targeted and non-targeted antiangiogenic drug activity and determine optimal biologic dose. Curr Cancer Drug Targets 5 (2005) 551-559
32. Bertolini F., Shaked Y., Mancuso P., and Kerbel R.S. The multifaceted circulating endothelial cell in cancer: towards marker and target identification. Nat Rev Cancer 6 (2006) 835-845
33. Georgantas III R.W., Tanadve V., Malehorn M., et al. Microarray and serial analysis of gene expression analyses identify known and novel transcripts overexpressed in hematopoietic stem cells. Cancer Res 64 (2004) 4434-4441
34. Ramalho-Santos M., Yoon S., Matsuzaki Y., Mulligan R.C., and Melton D.A. "Stemness": transcriptional profiling of embryonic and adult stem cells. Science 298 (2002) 597-600
35. Ivanova N.B., Dimos J.T., Schaniel C., Hackney J.A., Moore K.A., and Lemischka I.R. A stem cell molecular signature. Science 298 (2002) 601-604
36. Patterson L.J., Gering M., Eckfeldt C.E., et al. The transcription factors Scl and Lmo2 act together during development of the hemangioblast in zebrafish. Blood 109 (2007) 2389-2398
37. Jaffredo T., Bollerot K., Sugiyama D., Gautier R., and Drevon C. Tracing the hemangioblast during embryogenesis: developmental relationships between endothelial and hematopoietic cells. Int J Dev Biol 49 (2005) 269-277
38. Pandolfi P.P., Roth M.E., Karis A., et al. Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis. Nat Genet 11 (1995) 40-44
39. Thorsteinsdottir U., Mamo A., Kroon E., et al. Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion. Blood 99 (2002) 121-129
40. Rossig L., Urbich C., Bruhl T., et al. Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells. J Exp Med 201 (2005) 1825-1835
41. Crooks G.M., Fuller J., Petersen D., et al. Constitutive HOXA5 expression inhibits erythropoiesis and increases myelopoiesis from human hematopoietic progenitors. Blood 94 (1999) 519-528
42. Liao W., Ho C.Y., Yan Y.L., Postlethwait J., and Stainier D.Y. Hhex and scl function in parallel to regulate early endothelial and blood differentiation in zebrafish. Development 127 (2000) 4303-4313
43. Thomas P.Q., Brown A., and Beddington R.S. Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors. Development 125 (1998) 85-94
44. Kiger A.A., Jones D.L., Schulz C., Rogers M.B., and Fuller M.T. Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue. Science 294 (2001) 2542-2549
45. Tulina N., and Matunis E. Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling. Science 294 (2001) 2546-2549
46. Houbaviy H.B., Murray M.F., and Sharp P.A. Embryonic stem cell-specific MicroRNAs. Dev Cell 5 (2003) 351-358
47. Chen C.Z., Li L., Lodish H.F., and Bartel D.P. MicroRNAs modulate hematopoietic lineage differentiation. Science 303 (2004) 83-86
48. Esau C., Kang X., Peralta E., et al. MicroRNA-143 regulates adipocyte differentiation. J Biol Chem 279 (2004) 52361-52365
49. Conaco C., Otto S., Han J.J., and Mandel G. Reciprocal actions of REST and a microRNA promote neuronal identity. Proc Natl Acad Sci U S A 103 (2006) 2422-2427
50. Risau W., and Lemmon V. Changes in the vascular extracellular matrix during embryonic vasculogenesis and angiogenesis. Dev Biol 125 (1988) 441-450
51. Hynes R.O., Bader B.L., and Hodivala-Dilke K. Integrins in vascular development. Braz J Med Biol Res 32 (1999) 501-510
52. Yang J.T., Rayburn H., and Hynes R.O. Embryonic mesodermal defects in alpha 5 integrin-deficient mice. Development 119 (1993) 1093-1105
53. Jin H., Aiyer A., Su J., et al. A homing mechanism for bone marrow-derived progenitor cell recruitment to the neovasculature. J Clin Invest 116 (2006) 652-662
54. Llevadot J., Murasawa S., Kureishi Y., et al. HMG-CoA reductase inhibitor mobilizes bone marrow-derived endothelial progenitor cells. J Clin Invest 108 (2001) 399-405
55. Walter D.H., Dimmeler S., and Zeiher A.M. Effects of statins on endothelium and endothelial progenitor cell recruitment. Semin Vasc Med 4 (2004) 385-393
56. Nwokoro N.A., Wassif C.A., and Porter F.D. Genetic disorders of cholesterol biosynthesis in mice and humans. Mol Genet Metab 74 (2001) 105-119
57. Mori M., Li G., Abe I., et al. Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat. J Clin Invest 116 (2006) 395-404
58. Tozawa R., Ishibashi S., Osuga J., et al. Embryonic lethality and defective neural tube closure in mice lacking squalene synthase. J Biol Chem 274 (1999) 30843-30848