Modeled repetitive motion strain and indirect osteopathic manipulative techniques in regulation of human fibroblast proliferation and interleukin secretion

Journal of the American Osteopathic Association

Volumn 107, Issue 12, 2007, Pages 527-536

  Meltzer, Kate R ^a   Standley, Paul R ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 16; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 6;

ARTICLE; CELL ASSAY; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; OSTEOPATHIC MEDICINE; PROTEIN MICROARRAY; REPETITIVE STRAIN INJURY;

CELL PROLIFERATION; CELLS, CULTURED; COLORIMETRY; CUMULATIVE TRAUMA DISORDERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; HUMANS; INTERLEUKINS; MANIPULATION, OSTEOPATHIC;

EID: 38349018330     PISSN: 00986151     EISSN: 00986151     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Licciardone JC, Brimhall AK, King LN. Osteopathic manipulative treatment for low back pain: a systematic review and meta-analysis of randomized controlled trials [review]. BMC Musculoskelet Disord. 2005;6:43. Available at: http://www.biomedcentral.com/content/pdf/1471-2474-6-43.pdf. Accessed August 9, 2007.
2. Barnes JF. Myofascial release for craniomandibular pain and dysfunction. Int J Orofacial Myology. 1996;22:20-22.
3. Andersson GB, Lucente T, Davis AM, Kappler RE, Lipton JA, Leurgans S. A comparison of osteopathic spinal manipulation with standard care for patients with low back pain. N Engl J Med. 1999;341:1426-1431.
4. Sucher BM, Hinrichs RN, Welcher RL, Quiroz LD, St Laurent BF, Morrison BJ. Manipulative treatment of carpal tunnel syndrome: biomechanical and osteopathic intervention to increase the length of the transverse carpal ligament: part 2. Effect of sex difference and manipulative "priming." J Am Osteopath Assoc. 2005;105:135-143. Available at: http://www.jaoa.org/cgi/content/full/105/3/135. Accessed August 9, 2007.
5. Dodd JG, Good MM, Nguyen TL, Grigg AI, Batia LM, Standley PR. In vitro biophysical strain model for understanding mechanisms of osteopathic manipulative treatment. J Am Osteopath Assoc. 2006;106:157-166. Available at: http://www.jaoa.org/cgi/content/full/106/3/157. Accessed May 30, 2007.
6. Eagan T, Meltzer K, Standley P. Heterobiaxial and equiradial strain models of osteopathic manipulative treatments (OMTs): dichotomous regulation of human fibroblasts (HF) cell morphology and cytokine secretion [abstract]. J Am Osteopath Assoc. 2006;106:497. B06.
7. Wang PL, Ohura K, Fujii T, Oido-Mori M, Kowashi Y, Kikuchi M, et al. DNA microarray analysis of human gingival fibroblasts from healthy and inflammatory gingival tissues. Biochem Biophys Res Commun. 2003;305:970-973.
8. Pang G, Couch L, Batey R, Clancy R, Cripps A. GM-CSF, IL-1 alpha, IL-1beta, IL-6, IL-8, IL-10, ICAM-1, and VCAM-1 gene expression and cytokine production in human duodenal fibroblasts stimulated with lipopolysaccharide, IL-1 alpha, and TNF-alpha. Clin Exp Immunol. 1993;96:437-443.
9. Chen X, Hu J, He F, Ma J, Wu J, Zhang X. The effects of tensile strain and loading time on the secretion of IL-1 beta of human PDLF [in Chinese]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2002;19:652-656.
10. Ozawa A, Tada H, Sugawara Y, Uehara A, Sasano T, Shimauchi H, et al. Endogenous IL-15 sustains recruitment of IL-2Rβ and common γ and IL-2-mediated chemokine production in normal and inflamed human gingival fibroblasts. J Immunol. 2004;173:5180-5188. Available at: http://www.jimmunol.org/cgi/content/full/173/8/5180. Accessed November 28, 2006.
11. Speirs V, Birch MA, Boyle-Walsh E, Green AR, Gallagher JA, White MC. Interluekin-3: a putative protective factor against breast cancer which is secreted by male but not female breast fibroblasts. Int J Cancer. 1995;61:416-419.
12. Skutek M, van Griensven M, Zeichen J, Brauer N, Bosch U. Cyclic mechanical stretching enhances secretion of Interleukin 6 in human tendon fibroblasts. Knee Surg Sports Traumatol Arthrosc. 2001;9:322-326.
13. Harada S, Yamamura M, Okamoto H, Morita Y, Kawashima M, Aita T, et al. Production of interleukin-7 and interleukin-15 by fibroblast-like synoviocytes from patients with rheumatoid arthritis. Arthritis Rheum. 1999;42:1508-1516.
14. Cao JH, Han R, Smith TJ. Robust induction of PGHS-2 by IL-1 in orbital fibroblasts results from low levels of IL-1 receptor antagonist expression. Am J Physiol Cell Physiol. 2003;284:C1429-C1437. Available at: http://ajpcell.physiology.org/cgi/content/full/284/6/C1429. Accessed November 28, 2006.
15. Zurita-Salinas CS, Palacios-Boix A, Yanez A, Gonzalez F, Alcocer-Varela J. Contamination with Mycoplasma spp. induces interleukin-13 expression by human skin fibroblasts in culture. FEMS Immunol Med Microbiol. 1996;15:123-128.
16. Kaufmann J, Franke S, Kienstch-Engel R, Oelzner P, Hein G, Stein G. Correlation of circulating interleukin 16 with proinflammatory cytokines in patients with rheumatoid arthritis [letter]. Rheumatology. 2001;40:474-475. Available at: http://rheumatology.oxfordjournals.org/cgi/ reprint/40/4/474. Accessed November 28, 2006.
17. Vande Geest JP, DiMartino ES, Vorp DA. An analysis of the complete strain field within Flexercell membranes. J Biomech. 2004;37:1923-1928.
18. Lin Y, Huang R, Chen LP, Lisoukov H, Lu ZH, Li S, et al. Profiling of cytokine expression by biotin-labeled-based protein arrays. Proteomics. 2003;3:1750-1757.
19. Xu Y, Kulkosky J, Acheampong E, Nunnari G, Sullivan J, Pomerantz RJ. HIV-1-mediated apoptosis of neuronal cells: Proximal molecular mechanisms of HIV-1-induced encephalopathy. Proc Natl Acad Sci USA. 2004;101:7070-7075. Available at: http://www.pnas.org/cgi/content/full/101/18/7070. Accessed November 28, 2006.
20. Rapaport L, Robinson J. CellTiter 96 and CellTiter 96 AQeous Non-radioactive cell proliferation assays. Promega Notes Magazine. 1993;44:46. Available at: http://www.promega.com/pnotes/44/44p46/44p46_core.pdf. Accessed November 28, 2006.
21. Zernicke RF, Butler DL, Grood ES, Hefzy MS. Strain topography of human tendon and fascia. J Biomech Eng. 1984;106:177-180.
22. Woo SL, Debski RE, Withrow JD, Janaushek MA. Biomechanics of knee ligaments [review]. Am J Sports Med. 1999;27:533-543.
23. Webb K, Hitchcock RW, Smeal RM, Li W, Gray SD, Tresco PA. Cyclic strain increases fibroblast proliferation, matrix accumulation, and elastic modulus of fibroblast-seeded polyurethane constructs. J Biomech. 2006;39:1136-1144.
24. Glover JC, Rennie PR. Strain and counterstrain techniques. In: Ward RC, ed. Foundations for Osteopathic Medicine. 2nd ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2003:1002-1016,1150.
25. Jones L, Kusunose R, Goering E. Jones Strain-Counterstrain. Boise, Idaho: Jones Strain-CounterStrain, Inc; 1995.
26. Lim IJ, Phan TT, Bay BH, Qi R, Huynk H, Tan WT, et al. Fibroblasts cocultured with keloid keratinocytes: normal fibroblasts secrete collagen in keloid manner. Am J Physiol Cell Physiol. 2002;283:C212-C222. Available at: http://ajcell.physiology.org/cgi/content/full/283/1/C212. Accessed November 28, 2006.
27. Barkhausen T, van Griensven M, Zeichen J, Bosch U. Modulation of cell functions of human tendon fibroblasts by different repetitive cyclic mechanical stress patterns. Exp Toxicol Pathol. 2003;55:153-158.
28. Yang G, Crawford RC, Wang JH. Proliferation and collagen production of human patellar tendon fibroblasts in response to cyclic uniaxial stretching in serum-free conditions. J Biomech. 2004;37:1543-1550.
29. Lee AA, Delhaas T, McCulloch AD, Villarreal FJ. Differential responses of adult cardiac fibroblasts to in vitro biaxial strain patterns. J Mol Cell Cardiol. 1999;31:1833-1843.
30. He Y, Macarak EJ, Korostoff JM, Howard PS. Compression and tension: differential effects on matrix accumulation by periodontal ligament fibroblasts in vitro. Connect Tissue Res. 2004;45:28-39.
31. Sanchez-Esteban J, Wang Y, Cicchiello LA, Rubin LP. Cyclic mechanical stretch inhibits cell proliferation and induces apoptosis in fetal rat lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2002;282:L448-L456. Available at: http://ajplung.physiology.org/cgi/content/full/282/3/L448. Accessed November 28, 2006.
32. Palmer JN, Hartogensis WE, Patten M, Fortuin FD, Long CS. Interluekin-1 beta induces cardiac mycocyte growth but inhibits cardiac fibroblast proliferation in culture. J Clin Invest. 1995;95:2555-2564. Available at: http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid= 7769098. Accessed November 28, 2006.
33. Kuhn C III, Boldt J, King TE Jr, Crouch E, Vartio T, McDonald JA. An immunohistochemical study of architectural remodeling and connective tissue synthesis in pulmonary fibrosis. Am Rev Respir Dis. 1989;140:1693-1703.
34. Kjaer M. Role of extracellular matrix in adaptation of tendon and skeletal muscle to mechanical loading [review]. Physiol Rev. 2004;84:649-698. Available at: http://physrev.physiology.org/cgi/content/full/ 84/2/649. Accessed August 20, 2007.
35. Heinrich PC, Castell JV, Andus T. Interleukin-6 and the acute phase response [review]. Biochem J. 1990;265:621-636. Available at: http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1133681&blobtype=pdf. Accessed November 28, 2006.
36. Huang RP. Detection of multiple proteins in an antibody-based protein microarray system. J Immunol Methods. 2001;255:1-13.
37. Wang CC, Huang RP, Sommer M, Lisoukov H, Huang R, Lin Y, et al. Array-based multiplexed screening and quantitation of human cytokines and chemokines. J Proteome Res. 2002;1:337-343.
38. Gygi SP, Rochon Y, Franza BR, Aebersold R. Correlation between protein and mRNA abundance in yeast. Mol Cell Biol. 1999;19:1720-1730. Available at: http://mcb.asm.org/cgi/reprint/19/3/1720. Accessed November 28, 2006.
39. Zeichen J, van Griensven M, Bosch U. The proliferative response of isolated human tendon fibroblasts to cyclic biaxial mechanical strain. Am J Sports Med. 2000;28:888-892.
40. Shahar I, Fireman E, Topilsky M, Grief J, Kivity S, Spirer Z, et al. Effect of IL-6 on alveolar fibroblast proliferation in interstitial lung diseases. Clin Immunol Immunopathol. 1996;79:244-251.
41. Standiford TJ. Anti-inflammatory cytokines and cytokine antagonists. Curr Pharm Des. 2000;6:633-649. Available at: http://www.ingentaconnect. com/content/ben/cpd/2000/00000006/00000006/art00004?token=004c15257dfcf4e26 634a492f2530332976335a666f3a7b2f2d40424d2c6b664c23786738039. Accessed November 28, 2006.
42. Hildebrand F, Pape HC, Krettek C. The importance of cytokines in the posttraumatic inflammatory reaction [in German]. Unfallchirurg. 2005;108:793-794,796-803.
43. Smith LL, Anwar A, Fragen M, Rananto C, Johnson R, Holbert D. Cytokines and cell adhesion molecules associated with high-intensity eccentric exercise. Eur J Appl Physiol. 2000;82:61-67.
44. MacIntyre DL, Sorichter S, Mair J, Berg A, McKenzie DC. Markers of inflammation and myofibrillar proteins following eccentric exercise in humans. Eur J Appl Physiol. 2001;84:180-186.
45. Cytokines. In: Abbas AK, Lichtman AH, Pober JS. Cellular and Molecular Immunology. 4th ed. Philadelphia, Pa: WB Saunders Co; 2000:236-269.
46. Yang G, Im HJ, Wang JH. Repetitive mechanical stretching modulates IL-1beta induced COX-2, MMP-1 expression, and PGE2 production in human patellar tendon fibroblasts. Gene. 2005;363:166-172.
47. Lee RT, Briggs WH, Cheng GC, Rossiter HB, Libby P, Kupper T. Mechanical deformation promotes secretion of IL-1 alpha and IL-1 receptor antagonist. J Immunol. 1997;159:5084-5088.
48. Conti P, Panara MR, Porrini AM, Gambi D, Barbacane RC, Reale M, et al. Inhibition of interleukin-1 (alpha and beta), interleukin-2 secretion and surface expression of interleukin-2 receptor (IL-2R) by a novel cytokine interleukin-1 receptor antagonist (IL-1ra). Scand J Immunol. 1992;36:27-33.
49. Yang S, Wu B, Mayton L, Evans CH, Robbins PD, Wooley PH. IL-1Ra and vIL-10 gene transfer using retroviral vectors ameliorates particle-associated inflammation in the murine air pouch model. Inflamm Res. 2002;51:342-350.
50. Mori A, Suko M, Kaminuma O, Nishizaki Y, Mikami T, Ohmura T, et al. A critical role of IL-2 for the production and gene transcription of IL-5 in allergen-specific human T cell clones. Int Immunol. 1996;8:1889-1895. Available at: http://intimm.oxfordjournals.org/cgi/reprint/8/12/1889. Accessed November 28, 2006.
51. Kozanidou VI, Theocharis AD, Georgiadis A, Voulgari PV, Drosos AA, Karamanos NK. Signal transduction by IL-2 and its receptors as target in treatment of rheumatoid arthritis. Curr Drug Targets Immune Endocr Metabol Disord. 2005;5:41-50.
52. Cohen L, David B, Cavaillon J. Interleukin-3 enhances cytokine production by LPS-stimulated macrophages. Immunol Lett. 1991;28:121-126.
53. Seegert D, Rosenstiel P, Pfahler H, Pfefferkorn P, Nikolaus S, Schreiber S. Increased expression of IL-16 in inflammatory bowel disease. Gut. 2001;48:326-332.
54. Friedrich K, Kammer W, Erhardt I, Brandlein S, Arnold S, Sebald W. The two subunits of the interleukin-4 receptor mediate independent and distinct patterns of ligand endocytosis. Eur J Biochem. 1999;265:457-465. Available at: http://content.febsjournal.org/cgi/reprint/265/1/457. Accessed November 28, 2006.
55. Kamkin A, Kiseleva I, Isenberg G. Activation and inactivation of a nonselective cation conductance by local mechanical deformation of acutely isolated cardiac fibroblasts. Cardiovasc Res. 2003;57:793-803.
56. Plotkin BJ, Rodos JJ, Kappler R, Schrage M, Freydl K, Hasegawa S, et al. Adjunctive osteopathic manipulative treatment in women with depression: a pilot study. J Am Osteopath Assoc. 2001;101:517-523. Available at: http://www.jaoa.org/cgi/reprint/101/9/517. Accessed May 30, 2007.
57. Bretz WA, Weyant RJ, Corby PM, Ren D, Weissfeld L, Kritchevsky SB, et al. Systemic inflammatory markers, periodontal diseases, and periodontal infections in an elderly population. J Am Geriatr Soc. 2005;53:1532-1537.
58. Nemet D, Hong S, Mills PJ, Ziegler MG, Hill M, Cooper DM. Systemic vs local cytokine and leukocyte responses to unilateral wrist flexion exercise. J Appl Physiol. 2002;93:546-554. Available at: http://jap.physiology.org/ cgi/reprint/93/2/546. Accessed November 28, 2006.
59. Greenfeder S, Umland SP, Cuss FM, Chapman RW, Egan RW. Th2 cytokines and asthma-The role of interleukin-5 in allergic eosinophilic disease [review]. Respir Res. 2001;2:71-79. Available at: http://respiratory-research.com/ content/2/2/71. Accessed November 28, 2006.
60. Armitage RJ, Macduff BM, Ziegler SF, Grabstein KH. Multiple cytokine secretion by IL-7-stimulated human T cells. Cytokine. 1992;4:461-469.
61. Dokter WH, Sierdsema SJ, Esselink MT, Halie MR, Vellenga E. IL-7 enhances the expression of IL-3 and granulocyte-macrophage-CSF mRNA in activated human T cells by post-transcriptional mechanisms. J Immunol. 1993;150:2584-2590.
62. Kirman I, Vainer B, Nielsen OH. Interleukin-15 and its role in chronic inflammatory diseases. Inflamm Res. 1998;47:285-289.
63. Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest. 1999;103:779-788. Available at: http://www.jci.org/cgi/reprint/ 103/6/779. Accessed November 28, 2006.
64. Minty A, Chalon P, Derocq JM, Dumont X, Guillemot JC, Kaghad M, et al. Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature. 1993;362:248-250.