Biotransformation of metamitron by human P450 expressed in transgenic tobacco cell cultures

Journal of Environmental Science and Health - Part B Pesticides, Food Contaminants, and Agricultural Wastes

Volumn 41, Issue 3, 2006, Pages 201-222

  Bode, Maren ^a   Haas, Matthias ^a   Faymonville, Tanya ^b   Thiede, Brigitte ^b   Schuphan, Ingolf ^b   Schmidt, Burkhard ^b  

^a BAYER CROPSCIENCE AG   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Human CYP1A1 and CYP1A2; Metabolism; Metamitron; Oxidative metabolites; Tobacco; Transgenic plant cell cultures

Indexed keywords

ENZYMES; METABOLISM; TOBACCO;

HUMAN CYP1A1 AND CYP1A2; METAMITRON; OXIDATIVE METABOLITES; TRANSGENIC PLANT CELL CULTURES;

PLANT CELL CULTURE;

3 HYDROXYMETHYL 6 PHENYL 1,2,4 TRIAZIN 5(4H) ONE; 4 HYDROXYDEAMINOMETAMITRON; 6 HYDROXYPHENYL 3 METHOXYMETHYL 1,2,4 TRIAZIN 5(4H) ONE; CARBON 14; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; GLUCOSYLTRANSFERASE; HERBICIDE; METAMITRON; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

BIOTRANSFORMATION;

AEROBIC METABOLISM; ARTICLE; BIOTRANSFORMATION; CELL CULTURE; CONTROLLED STUDY; DEAMINATION; GAS CHROMATOGRAPHY; GENE OVEREXPRESSION; GLYCOSYLATION; HYDROXYLATION; INCUBATION TIME; MASS SPECTROMETRY; NONHUMAN; PLANT CELL; TRANSGENIC PLANT; TURNOVER TIME;

BIOTRANSFORMATION; CARBON RADIOISOTOPES; CELL CULTURE TECHNIQUES; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; HERBICIDES; HUMANS; PLANTS, GENETICALLY MODIFIED; RADIOISOTOPE DILUTION TECHNIQUE; TOBACCO; TRIAZINES;

ENZYMES; METABOLISM; TOBACCO;

NICOTIANA TABACUM;

EID: 32644439435     PISSN: 03601234     EISSN: 15324109     Source Type: Journal    
DOI: 10.1080/03601230500354758     Document Type: Article

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