Laboratory Evaluation of the Antiphospholipid Syndrome

Hematology/Oncology Clinics of North America

Volumn 22, Issue 1, 2008, Pages 19-32

  Hoppensteadt, Debra A ^a   Fabbrini, Nancy ^b   Bick, Rodger L ^c   Messmore, Harry L ^d   Adiguzel, Cafar ^d   Fareed, Jawed ^d  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b HINES VA HOSPITAL   (United States)

^c NONE   (United States)

^d LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLIPIN ANTIBODY; LUPUS ANTICOAGULANT; PHOSPHOLIPID ANTIBODY;

ANTIPHOSPHOLIPID SYNDROME; EVOLUTIONARY ADAPTATION; HEMOSTASIS; HUMAN; LABORATORY TEST; PLASMA; PRIORITY JOURNAL; REVIEW; SCREENING; THROMBIN TIME; THROMBOCYTE ANOMALY; THROMBOPHILIA;

ALGORITHMS; ANTIPHOSPHOLIPID SYNDROME; BLOOD COAGULATION TESTS; HUMANS; LUPUS COAGULATION INHIBITOR; THROMBOPHILIA;

EID: 38348998842     PISSN: 08898588     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hoc.2007.10.009     Document Type: Review

References (47)

1. Bick R.L., Jakway J., and Baker W.F. Deep vein thrombosis: prevalence of etiologic factors and results of management in 100 consecutive patients. Semin Thromb Hemost 18 (1992) 267-274
2. Bick R.L., and Baker W.F. Anticardiolipin antibodies and thrombosis. Hematol Oncol Clin North Am 6 (1992) 1287-1299
3. Fritsma G.A., and Marques M.B. Thrombosis risk testing. In: Rodah B.F., Fritsma G.A., and Doig K. (Eds). Hematology: clinical principles and applications (2007), Saunders Elsevier, St. Louis (MO) 605-628
4. Triplett D.A. Laboratory diadnosis of lupus anticoagulant. Semin Thromb Hemost 16 (1990) 182-192
5. Conle C.L., and Hartmann R.C. A hemorrhagic disorder caused by circulating anticoagulants in patients with disseminated lupus erythematosus. J Clin Invest 31 (1952) 621-622
6. Bowie E.J.W., Thompson J.H., Pascuzzi C.A., et al. Thrombosis in systemic lupus erythematosus despite circulating anticoagulants. J Lab Clin Med 62 (1963) 416-430
7. Alarcon-Segovia D. Clinical manifestations of the antiphospholipid syndrome. J Rheumatol 18 (1992) 1916-1918
8. Triplett D.A. Antiphospholipid antibodies and thrombosis. A consequence, coincidence, or cause?. Arch Pathol Lab Med 117 (1993) 78-88
9. Harris E.N., Gharavi A.E., and Boey M.L. Anticardiolipin antibodies: detection by radioimmunoassays and association with thrombosis in systemic lupus erythematosus. Lancet 2 (1983) 1211-1214
10. Bick R.L., and Ucar K. Hypercoagulability and thrombosis. Hematol Oncol Clin North Am 6 (1992) 1421-1431
11. Triplett D.A. Antiphospholipid antibodies. In: Hathway W.E., and Goodnight S.H. (Eds). Disorders of hemostasis and thrombosis. 2nd edition (2001), McGraw-Hill, New York 405-419
12. Angles-Cano E., Sultan Y., and Clauvel J.P. Predisposing factors to thrombosis in systemic lupus erythematosus: possible relation to endothelial damage. J Lab Clin Med 94 (1979) 317-323
13. Nakamura N., Kawasaki C., Shidara Y., et al. Antibody to annexin V has anti-phospholipid and lupus anticoagulant properties. Am J Hematol 49 (1995) 347-348
14. Kaburaki J., Kuwan M., Yamamoto M., et al. Clinical significance of anti-annexin V antibodies in patients with systemic lupus erythematosus. Am J Hematol 54 (1997) 209-213
15. Lie J.T. Vasculopathy of the antiphospholipid syndromes revisited: thrombosis is the culprit and vasculitis the consort. Lupus 5 (1966) 368-371
16. Lopez-Pedrera C., Buendia P., Barbarroja N., et al. Antiphospholipid mediated thrombosis: interplay between anticardiolipin antibodies and vascular cells. Clin Appl Thromb Hemost 12 (2006) 41-45
17. McNeil H.P., Simpson R.J., Chesterman C.N., et al. Antiphospholipid antibodies are directed against a complex antigen that includes a lipid binding inhibitor of coagulation: 2 glycoprotein I (apolipoprotein H). Proc Natl Acad Sci U S A 87 (1990) 4120-4124
18. Miesbach W., Matthias T., and Scharrer I. Identification of thrombin antibodies in patients with antiphospholipid syndrome. Ann N Y Acad Sci 1050 (2005) 250-256
19. Bertolaccini M.L., and Hughes G.R. Antiphospholipid antibody testing: which are most useful for diagnosis?. Rheum Dis Clin North Am 32 (2006) 455-463
20. Roubey A.S. Autoantibodies to phospholipid-binding plasma proteins: a new view of lupus anticoagulants and other "antiphospholipid" autoantibodies. Blood 84 (1994) 2854-2867
21. Oosting J.D., Derksen R.H.W.M., Bobbick I.W.G., et al. Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C or protein S. An explanation for their pathogenic mechanism. Blood 81 (1993) 2618-2625
22. Matsuda J., Gotoh M., Saith M., et al. Anti-annexin antibody in the sera of patients with habitual fetal loss or pre-eclampsia. Thromb Res 75 (1994) 105-106
23. Teruya J., West A.G., and Suell M.N. Lupus anticoagulant assays: questions answered and to be answered. Arch Pathol Lab Med 131 6 (2007) 885-889
24. Exner T., Triplett D.A., Taberner D., et al. Guidelines for testing and revised criteria for lupus anticoagulants. Thromb Haemost 65 (1991) 320-322
25. Brandt J.T., Triplett D.A., Alving B., et al. Criteria for the diagnosis of lupus anticoagulants, an update on behalf of the subcommittee on lupus anticoagulants/antiphospholipid antibodies of the ISTH. Thromb Haemost 74 (1995) 1597-1603
26. Greaves M., Cohen H., Machin S.J., et al. Guidelines on the investigation and management of the antiphospholipid syndrome. Br J Haematol 109 (2000) 704-715
27. Acosta M., Edwards R., Jaffe E.I., et al. Practical approach to pediatric patients referred with an abnormal coagulation profile. Arch Pathol Lab Med 129 (2005) 1011-1016
28. Bick R.L., and Baker W.F. Antiphospholipid syndrome and thrombosis. Semin Thromb Hemost 25 (1999) 333-339
29. Kunkel L. Acquired circulating anticoagulants. Hematol Oncol Clin North Am 6 (1992) 1341-1358
30. Mackie I.J., Lawie A.S., Greenfield R.S., et al. A new lupus anticoagulant test based on dilute prothrombin time. Thromb Res 114 (2004) 673-674
31. Genzen J.R., and Miller J.L. Presence of direct thrombin inhibitors can affect the results interpretation of lupus anticoagulant testing. Am J Clin Pathol 124 4 (2005) 586-593
32. Zhang L., Whitis J.G., Embry M.B., et al. A simplified algorithm for the laboratory detection of lupus anticoagulants. Utilization of two automated integrated tests. Am J Clin Pathol 124 (2005) 894-901
33. Triplett D.A., et al. Laboratory evaluation of circulating anticoagulants. In: Bick R.L., Bennett R.M., and Byrnes R.K. (Eds). Hematology: clinical and laboratory practice (1993), C.V. Mosby Publisher, Saint Louis (MO) 1539-1548
34. Mannucci P.M., Canciani M.T., Mari D., et al. The varied sensitivity of partial thromboplastin and prothrombin time reagents in the demonstration of the lupus-like inhibitor. Scand J Haematol 22 (1979) 423-432
35. Thiagarajan P., Pengo V., and Shapiro S.S. The use of the diluted Russel viper venom time for the diagnosis of lupus anticoagulants. Blood 68 (1986) 869-874
36. Teruya J., West A.G., and Suell M.N. Lupus anticoagulant assays. Arch Pathol Lab Med 131 (2007) 885-889
37. Laux V., Hinder M., et al. Rationale for direct factor Xa inhibitors in acute coronary syndromes. In: Kipshidze N.N., Fareed J., and Mosses J.W. (Eds). Textbook of international cardiovascular pharmacology (2007), Informa Healthcare, London 119-126
38. Bick R.L. The antiphospholipid thrombosis syndromes: a common multidisciplinary medical problem. Clin Appl Thromb Hemost 3 (1997) 270-283
39. Rauch J., Tannenbaum M., and Janoff A.S. Distinguishing plasma lupus anticoagulants from anti-factor antibodies using hexagonal (II) phase phospholipids. Thromb Haemost 62 (1989) 892-896
40. Kandiah D.A., Sheng Y.H., and Krilis S.A. Beta-2 glycoprotein I: target antigen for autoantibodies in the:antiphospholipid symdrome. Lupus 5 (1996) 381-386
41. Falcon C.R., Hoffer A.M., Forastiero R.R., et al. Clinical significance of various ELISA assays for detecting antiphospholipid antibodies. Thromb Haemost 64 (1990) 21-25
42. Rudge A.C., Reynolds R., Bolye C.C., et al. Measurement of anti-cardiolipin antibodies by an enzyme-linked immunosorbent assay (ELISA): standardization and quantization of results. Clin Exp Immunol 62 (1985) 738-745
43. Reyes H., Dearing L., and Shoenfeld Y. Antiphospholipid antibodies: a critique of their heterogeneity and hegemony. Semin Thromb Hemost 20 (1994) 89-100
44. Cabral A.R., Amigo M.C., Cabiedes J., et al. The antiphospholipid/cofactor syndromes: a primary variant with antibodies to beta-2-glycoprotein-I but no antibodies detectable in standard antiphospholipid assays. Am J Med 101 (1996) 472-481
45. Falcon C.R., Hoffer A.M., and Carreras L.O. Antiphosphatidylinositol antibodies as markers of the antiphospholipid syndrome. Thromb Res 63 (1990) 321-322
46. Falcon C.R., Hoffer A.M., and Carreras L.O. Evaluation of the clinical and laboratory association of antiphosphatodylethanolamine antibodies. Thromb Res 59 (1990) 383-388
47. Lupus anticoagulant/phospholipid-dependent antibodies 2007 SSC Subcommittee minutes. Avaialable at: http://www.med.unc.edu/isth/SSC/07sscminutes/07luous.htm. Accessed September 3, 2007.