On the determination of the time delay in reaching the steady state drug concentration in the organ compared to plasma

Journal of Pharmaceutical Sciences

Volumn 96, Issue 12, 2007, Pages 3432-3443

  Berezhkovskiy, Leonid M ^a  

^a GENENTECH INC   (United States)

Author keywords

Brain distribution kinetics; In vivo based pharmacokinetic model; Kinetics of drug distribution into tissue; Steady state volume of distribution; Terminal half life; Terminal volume of distribution; Time of reaching the steady state in plasma and tissue

Indexed keywords

AREA UNDER THE CURVE; ARTICLE; BLOOD LEVEL; DRUG CONCENTRATION; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG RESEARCH; IN VIVO STUDY; MATHEMATICAL ANALYSIS; PLASMA;

EID: 38149127081     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20986     Document Type: Article

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