Classification of estrogen receptor-β ligands on the basis of their binding affinities using support vector machine and linear discriminant analysis

European Journal of Medicinal Chemistry

Volumn 43, Issue 1, 2008, Pages 43-52

  Luan, F ^a   Liu, H T ^a   Ma, W P ^b   Fan, B T ^c  

^a YANTAI UNIVERSITY   (China)

^b LANZHOU UNIVERSITY   (China)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Classification; Estrogen receptor ; Linear discriminant analysis; Support vector machine; The heuristic method

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR BETA; ISOXAZOLE DERIVATIVE; METALLOTHIONEIN; NAPHTHYL BENZISOXAZOLE; PHENYL BENZISOXAZOLE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; SOMATOMEDIN BINDING PROTEIN 4; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; MACHINE LEARNING; OSTEOSARCOMA CELL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATISTICAL MODEL; SUPPORT VECTOR MACHINE;

ARTIFICIAL INTELLIGENCE; DISCRIMINANT ANALYSIS; ESTROGEN RECEPTOR BETA; INHIBITORY CONCENTRATION 50; LIGANDS; LINEAR MODELS; SENSITIVITY AND SPECIFICITY;

EID: 38149119794     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.03.002     Document Type: Article

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