Synthesis and biological evaluation of helicid analogues as novel acetylcholinesterase inhibitors

European Journal of Medicinal Chemistry

Volumn 43, Issue 1, 2008, Pages 166-173

  Wen, Huan ^a   Lin, Chonglan ^a   Que, Ling ^a   Ge, Hui ^a   Ma, Lin ^a   Cao, Rihui ^a   Wan, Yiqian ^a   Peng, Wenlie ^a   Wang, Zihou ^b   Song, Huacan ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b State Drug Administration   (China)

Author keywords

4 Hydroxybenzaldeyde; Cholinesterase inhibitor; Helicid analogues

Indexed keywords

1 [4 (O BETA DEXTRO GLUCOPYRANOSYL)BENZYLIDENE]METHOXYAMINE; 4 FORMYLPHENYL O BETA DEXTRO GLUCOPYRANOSIDE; 4 FORMYLPHENYL O BETA DEXTRO RIBOPYRANOSIDE; ACETYLCHOLINESTERASE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; GALANTAMINE; HELICID ANALOG; UNCLASSIFIED DRUG;

ARTICLE; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; IN VITRO STUDY; ULTRAVIOLET SPECTROSCOPY;

ACETYLCHOLINESTERASE; BENZALDEHYDES; BIOLOGICAL PRODUCTS; CHOLINESTERASE INHIBITORS; DRUG EVALUATION, PRECLINICAL; GLYCOSIDES; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; SCHIFF BASES; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 38149105897     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.03.018     Document Type: Article

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