Molecular modelling and QSAR of reversible Acetylcholinesterase inhibitors

Current Medicinal Chemistry

Volumn 7, Issue 3, 2000, Pages 273-294

  Kaur, J ^a   Zhang, M Q ^a  

^a Organen Laboratories Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLAMINE DERIVATIVE; CHOLINESTERASE INHIBITOR; DONEPEZIL; HUPERZINE A; NEOSTIGMINE; PHYSOSTIGMINE; TACRINE;

ALZHEIMER DISEASE; DRUG INDICATION; DRUG STRUCTURE; ENZYME ACTIVE SITE; GLAUCOMA; HYDROPHOBICITY; MOLECULAR MODEL; MOLECULAR RECOGNITION; MYASTHENIA GRAVIS; NEUROMUSCULAR BLOCKING; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; X RAY CRYSTALLOGRAPHY;

EID: 0034098363     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867003375254     Document Type: Review

References (17)

1. Dale, H.H. J. Pharmacol. Exp. Ther., 1914, 6, 147.
2. Caulfield, M.P.; Birdsall, N.J.M. Pharmacol. Rev., 1998, 50, 279.
3. Colquhoun, L.M.; Patrick, J.W. Adv. Pharmacol. 1997, 39, 191.
4. Argyll-Robinson, D. Edinburgh Med. J., 1863, 8, 815.
5. Rees, D.C.; Hill D. Annual Rep. Med Chem., 1996, 31, 41.
6. Wittbrodt, E.T. Arch. Intern. Med., 1997, 24, 157.
7. Millard, C.B.; Broomfield, C.A. J. Neurochem., 1995, 64, 1909.
8. Taylor, P. Neurology 1998, 51(1 Suppl 1), S30.
9. Hucho, F. J. Neural. Transm. Suppl., 1995; 46, 59
10. Makhaeva, G.F.; Filonenko, I.V.; Yankovskaya, V.L.; Fomicheva, S.B.; Malygin, V.V. NeuroToxicology, 1998, 19, 623.
11. Maxwell, D.M.; Brecht, K.M. Chem. Res. Toxicol., 1992, 5, 66.
12. Hansch, C. In Computer Aided Molecular Design; Reynolds C.N., Holloway M.K., Cox A.K., Eds.; American Chemical Society; Washington, DC, 1995, pp. 281-291.
13. Greenfield, S.A. Cell Mol. Neurobiol., 1991, 11, 55
14. Brown, S.S.; Kalow, W.; Pilz, W.; Whittaker, M.; Woronick, C.L. Adv. Clin. Chem. 1981, 22, 1.
15. Inestrosa, N.C.; Perelman, A. Trends Pharmacol. Sci. 1989, 10, 325.
16. Fernandez, H.L.; Moreno, R.D.; Inestrosa, N.C. J. Neurochem. 1996, 66, 1335.
17. Enz, A.; Amstutz, R.; Roddeke, H.; Gmelin, G.; Malanowski, J. In Progress in Brain Research; Cuello, A.C., Ed., Elsevier Publishers, 1993, Vol. 98, pp431-438.