Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 gene point mutations in Japanese patients with gastric cancer

Journal of Gastroenterology

Volumn 39, Issue 3, 2004, Pages 220-230

  Suzuki, Shioto ^a,b   Muroishi, Youko ^a   Nakanishi, Isao ^a   Oda, Yoshio ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Alcohol; Gastric cancer; Genetic susceptibility; Metabolizing enzyme polymorphism; p53 gene point mutation

Indexed keywords

ACYLTRANSFERASE; CYTOCHROME P450 1A1; CYTOCHROME P450 2E1; DNA; DRUG METABOLIZING ENZYME; GLUTATHIONE TRANSFERASE; PROTEIN P53;

ADULT; AGED; ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; AUTOPSY; CANCER CLASSIFICATION; CANCER PATIENT; CANCER RISK; CARCINOGENESIS; CONTROLLED STUDY; DRINKING BEHAVIOR; EXON; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HELICOBACTER PYLORI; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; JAPAN; MAJOR CLINICAL STUDY; MALE; MOLECULAR MECHANICS; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; STOMACH CANCER; STOMACH MUCOSA;

ADULT; AGED; AGED, 80 AND OVER; ALCOHOLISM; ARYL HYDROCARBON HYDROXYLASES; ARYLAMINE N-ACETYLTRANSFERASE; CASE-CONTROL STUDIES; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2E1; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; JAPAN; MALE; MIDDLE AGED; POINT MUTATION; POLYMORPHISM, GENETIC; STOMACH NEOPLASMS;

EID: 1942536469     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00535-003-1281-x     Document Type: Article

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