The interaction with Sp1 and reduction in the activity of histone deacetylase 1 are critical for the constitutive gene expression of IL-1α in human melanoma cells

Journal of Leukocyte Biology

Volumn 83, Issue 1, 2008, Pages 190-199

  Enya, Kazuaki ^a   Hayashi, Hidetoshi ^a   Takii, Takemasa ^a   Ohoka, Nobumichi ^a   Kanata, Shinya ^a   Okamoto, Takashi ^b   Onozaki, Kikuo ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Chromatin immunoprecipitation; HDAC; Trichostatin A

Indexed keywords

HISTONE DEACETYLASE 1; INTERLEUKIN 1ALPHA; MESSENGER RNA; NUCLEOTIDE; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; TRICHOSTATIN A;

ARTICLE; CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA BINDING; DRUG MECHANISM; ENZYME ACTIVITY; GENE ACTIVATION; GENE EXPRESSION; GENE SEQUENCE; GENETIC REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MELANOMA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; TRANSACTIVATION;

CELL LINE, TUMOR; DNA; ENZYME ACTIVATION; GENE EXPRESSION PROFILING; HISTONE DEACETYLASES; HUMANS; INTERLEUKIN-1ALPHA; MELANOMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SP1 TRANSCRIPTION FACTOR; SP3 TRANSCRIPTION FACTOR; TUMOR CELLS, CULTURED;

EID: 38149059720     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0106008     Document Type: Article

References (48)

1. Dinarello, C. A. (1996) Biologic basis for interleukin-1 in disease. Blood 87, 2095-2147.
2. Shirakawa, F., Saito, K., Bonagura, C. A., Galson, D. L., Fenton, M. J., Webb, A. C., Auron, P. E. (1993) The human prointerleukin 1 β gene requires DNA sequences both proximal and distal to the transcription start site for tissue-specific induction. Mol. Cell. Biol. 13, 1332-1344.
3. Cogswell, J. P., Godlevski, M. M., Wisely, G. B., Clay, W. C., Leesnitzer, L. M., Ways, J. P., Gray, J. G. (1994) NF-κ B regulates IL-1 β transcription through a consensus NF-κ B binding site and a nonconsensus CRE-like site. J. Immunol. 153, 712-723.
4. Furutani, Y. (1994) Molecular studies on interleukin-1 α. Eur. Cytokine Netw. 5, 533-538.
5. Kupper, T. S., Chua, A. O., Flood, P., McGuire, J., Gubler, U. (1987) Interleukin 1 gene expression in cultured human keratinocytes is augmented by ultraviolet irradiation. J. Clin. Invest. 80, 430-436.
6. Maier, J. A., Voulalas, P., Roeder, D., Maciag, T. (1990) Extension of the life-span of human endothelial cells by an interleukin-1 α antisense oligomer. Science 249, 1570-1574.
7. Shirakawa, F., Tanaka, Y., Oda, S., Eto, S., Yamashita, U. (1989) Autocrine stimulation of interleukin 1 α in the growth of adult human T-cell leukemia cells. Cancer Res. 49, 1143-1147.
8. Tyler, D. S., Francis, G. M., Frederick, M., Tran, A. H., Ordonez, N. G., Smith, J. L., Eton, O., Ross, M., Grimm, E. A. (1995) Interleukin-1 production in tumor cells of human melanoma surgical specimens. J. Interferon Cytokine Res. 15, 331-340.
9. Burke, F., Relf, M., Negus, R., Balkwill, F. (1996) A cytokine profile of normal and malignant ovary. Cytokine 8, 578-585.
10. Mangge, H., Kenzian, H., Gallistl, S., Neuwirth, G., Liebmann, P., Kaulfersch, W., Beaufort, F., Muntean, W., Schauenstein, K. (1995) Serum cytokines in juvenile rheumatoid arthritis. Correlation with conventional inflammation parameters and clinical subtypes. Arthritis Rheum. 38, 211-220.
11. Lundberg, I., Ulfgren, A. K., Nyberg, P., Andersson, U., Klareskog, L. (1997) Cytokine production in muscle tissue of patients with idiopathic inflammatory myopathies. Arthritis Rheum. 40, 865-874.
12. Kawaguchi, Y., Hara, M., Wright, T. M. (1999) Identification of an IL1A gene segment that determines aberrant constitutive expression of interleukin-1 α in systemic sclerosis. J. Clin. Invest. 103, 1253-1260.
13. Kronborg, G., Hansen, M. B., Svenson, M., Fomsgaard, A., Hoiby, N., Bendtzen, K. (1993) Cytokines in sputum and serum from patients with cystic fibrosis and chronic Pseudomonas aeruginosa infection as markers of destructive inflammation in the lungs. Pediatr. Pulmonol. 15, 292-297.
14. Sandborg, C. I., Berman, M. A., Imfeld, K. L., Cesario, T. C., Zaldivar Jr., F. (1990) Interleukin-1 and a 7-kDa T-cell inhibitory monokine reflect disease activity in infection with HIV-1. J. Acquir. Immune Defic. Syndr. 3, 1148-1154.
15. Tomimatsu, S., Ichikura, T., Mochizuki, H. (2001) Significant correlation between expression of interleukin-1α and liver metastasis in gastric carcinoma. Cancer 91, 1272-1276.
16. Huleihel, M., Maymo, E., Piura, B., Prinsloo, I., Benharroch, D., Yanai-Inbar, I., Glezerman, M. (1997) Distinct patterns of expression of interleukin-1 α and β by normal and cancerous human ovarian tissues. Eur. Cytokine Netw. 8, 179-187.
17. Ensoli, B., Nakamura, S., Salahuddin, S. Z., Biberfeld, P., Larsson, L., Beaver, B., Wong-Staal, F., Gallo, R. C. (1989) Kaposi's sarcoma cells: long-term culture with growth factor from retrovirus-infected CD4 T cells. Science 243, 223-226.
18. Kumar, S., Vinci, J. M., Millis, A. J., Baglioni, C. (1993) Expression of interleukin-1 α and β in early passage fibroblasts from aging individuals. Exp. Gerontol. 28, 505-513.
19. Chirivi, R. G., Garofalo, A., Padura, I. A., Mantovani, A., Giavazz, R. (1993) Interleukin 1 receptor antagonist inhibits the augmentation of metastasis induced by interleukin 1 or lipopolysaccharide in a human melanoma/nude mouse system. Cancer Res. 53, 5051-5054.
20. Krasagakis, K., Garbe, C., Orfanos, C. E. (1993) Cytokines in human melanoma cells: synthesis, autocrine stimulation and regulatory functions - an overview. Melanoma Res. 3, 425-433.
21. Lu, C., Rak, J. W., Kobayashi, H., Kerbel, R. S. (1993) Increased resistance to oncostatin M-induced growth inhibition of human melanoma cell lines derived from advanced-stage lesions. Cancer Res. 53, 2708-2711.
22. Onozaki, K., Matsushima, K., Aggarwal, B. B., Oppenheim, J. J. (1985) Human interleukin 1 is a cytocidal factor for several tumor cell lines. J. Immunol. 135, 3962-3968.
23. Endo, Y., Matsushima, K., Onozaki, K., Oppenheim, J. J. (1988) Role of ornithine decarboxylase in the regulation of cell growth by IL-1 and tumor necrosis factor. J. Immunol. 141, 2342-2348.
24. Araki, M., Yano, T., Hayashi, H., Takii, T., Suzuki, K., Onozaki, K. (1994) Resistance to the anti-proliferative effect of IL-1 on human melanoma cell line is associated with endogenous production of IL-1 and IL-6. Int. J. Cancer 56, 275-280.
25. Hayashi, H., Shimizu, R., Fujii, K., Itoh, S., Yang, D., Onozaki, K. (1997) Resistance to IL-1 anti-proliferative effect, accompanied by characteristics of advanced melanoma, permits invasion of human melanoma cells in vitro, but not metastasis in the nude mouse. Int. J. Cancer 71, 416-421.
26. Kimura, H., Inukai, Y., Takii, T., Furutani, Y., Shibata, Y., Hayashi, H., Sakurada, S., Okamoto, T., Inoue, J., Oomoto, Y., Onozaki, K. (1998) Molecular analysis of constitutive IL-1α gene expression in human melanoma cells: autocrine stimulation through NF-κB activation by endogenous IL-1α. Cytokine 10, 872-879.
27. Botella, L. M., Sanchez-Elsner, T., Sanz-Rodriguez, F., Kojima, S., Shimada, J., Guerrero-Esteo, M., Cooreman, M. P., Ratziu, V., Langa, C., Vary, C. P., Ramirez, J. R., Friedman, S., Bernabeu, C. (2002) Transcriptional activation of endoglin and transforming growth factor-β signaling components by cooperative interaction between Sp1 and KLF6: their potential role in the response to vascular injury. Blood 100, 4001-4010.
28. Udvadia, A. J., Templeton, D. J., Horowitz, J. M. (1995) Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression. Proc. Natl. Acad. Sci. USA 92, 3953-3957.
29. Ohata, H., Tetsuka, T., Hayashi, H., Onozaki, K., Okamoto, T. (2003) 3-Methylcholanthrene activates human immunodeficiency virus type 1 replication via aryl hydrocarbon receptor. Microbiol. Immunol. 47, 363-370.
30. Tamaki, A., Hayashi, H., Nakajima, H., Takii, T., Katagiri, D., Miyazawa, K., Hirose, K., Onozaki, K. (2004) Polycyclic aromatic hydrocarbon increases mRNA level for interleukin 1 β in human fibroblast-like synoviocyte line via aryl hydrocarbon receptor. Biol. Pharm. Bull. 27, 407-410.
31. Suske, G. (1999) The Sp-family of transcription factors. Gene 238, 291-300.
32. Reisinger, K., Kaufmann, R., Gille, J. (2003) Increased Sp1 phosphorylation as a mechanism of hepatocyte growth factor (HGF/SF)-induced vascular endothelial growth factor (VEGF/VPF) transcription. J. Cell Sci. 116, 225-238.
33. Lagger, G., Doetzlhofer, A., Schuettengruber, B., Haidweger, E., Simboeck, E., Tischler, J., Chiocca, S., Suske, G., Rotheneder, H., Wintersberger, E., Seiser, C. (2003) The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene. Mol. Cell. Biol. 23, 2669-2679.
34. De Ruijter, A. J., van Gennip, A. H., Caron, H. N., Kemp, S., van Kuilenburg, A. B. (2003) Histone deacetylases (HDACs): characterization of the classical HDAC family. Biochem. J. 370, 737-749.
35. Zhu, W. G., Srinivasan, K., Dai, Z., Duan, W., Druhan, L. J., Ding, H., Yee, L., Villalona-Calero, M. A., Plass, C., Otterson, G. A. (2003) Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter. Mol. Cell. Biol. 23, 4056-4065.
36. Bouwman, P., Philipsen, S. (2002) Regulation of the activity of Sp1-related transcription factors. Mol. Cell. Endocrinol. 195, 27-38.
37. Zhang, F., Su, K., Yang, X., Bowe, D. B., Paterson, A. J., Kudlow, J. E. (2003) O-GlcNAc modification is an endogenous inhibitor of the proteasome. Cell 115, 715-725.
38. Shi, Q., Le, X., Abbruzzese, J. L., Peng, Z., Qian, C. N., Tang, H., Xiong, Q., Wang, B., Li, X. C., Xi, K. (2001) Constitutive Sp1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma. Cancer Res. 61, 4143-4154.
39. Gottlieb, T. M., Jackson, S. P. (1993) The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72, 131-142.
40. Suzuki, T., Kimura, A., Nagai, R., Horikoshi, M. (2000) Regulation of interaction of the acetyltransferase region of p300 and the DNA-binding domain of Sp1 on and through DNA binding. Genes Cells 5, 29-41.
41. Yang, X., Su, K., Roos, M. D., Chang, Q., Paterson, A. J., Kudlow, J. E. (2001) O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability. Proc. Natl. Acad. Sci. USA 98, 6611-6616.
42. Trisciuoglio, D., Iervolino, A., Candiloro, A., Fibbi, G., Fanciul, M., Zangemeister-Wittke, U., Zupi, G., Del Bufalo, D. (2004) bcl-2 induction of urokinase plasminogen activator receptor expression in human cancer cells through Sp1 activation: involvement of ERK1/ERK2 activity. J. Biol. Chem. 279, 6737-6745.
43. Juan, L. J., Shia, W. J., Chen, M. H., Yang, W. M., Seto, E., Lin, Y. S., Wu, C. W. (2000) Histone deacetylases specifically down-regulate p53-dependent gene activation. J. Biol. Chem. 275, 20436-20443.
44. Doetzlhofer, A., Rotheneder, H., Lagger, G., Koranda, M., Kurtev, V., Brosch, G., Wintersberger, E., Seiser, C. (1999) Histone deacetylase 1 can repress transcription by binding to Sp1. Mol. Cell. Biol. 19, 5504-5511.
45. Yamashita, Y., Shimada, M., Harimoto, N., Rikimaru, T., Shirabe, K., Tanaka, S., Sugimachi, K. (2003) Histone deacetylase inhibitor trichostatin A induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells. Int. J. Cancer 103, 572-576.
46. Barnes, P. J., Ito, K., Adcock, I. M. (2004) Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase. Lancet 363, 731-733.
47. Cosio, B. G., Mann, B., Ito, K., Jazrawi, E., Barnes, P. J., Chung, K. F. (2004) Histone acetylase and deacetylase activity in alveolar macrophages and blood monocytes in asthma. Am. J. Respir. Crit. Care Med. 170, 141-147.
48. Ito, K., Lims, S., Caramori, G., Chung, K. F., Barnes, M., Adcock, I. M., Barnes, P. J. (2001) Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression and inhibits glucocorticoid actions in alveolar macrophages. FASEB J. 15, 1110-1112.