New-Onset Seizures: A Possible Association With Clonidine?

Pediatric Neurology

Volumn 38, Issue 2, 2008, Pages 147-149

  Feron, Frans J M ^a   Hendriksen, Jos G M ^b   Nicolai, Joost ^b   Vles, Johan S H ^b  

^a Regional Public Health Institute Maastricht   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; CLONIDINE; DIAZEPAM; METHYLPHENIDATE; MIDAZOLAM; PHENYTOIN;

ANAMNESIS; ARTICLE; ATTENTION DEFICIT DISORDER; CASE REPORT; CLINICAL FEATURE; DISEASE ASSOCIATION; DRUG DOSE INCREASE; DRUG WITHDRAWAL; ELECTROCARDIOGRAM; EPILEPTIC STATE; FAMILY HISTORY; FEMALE; HUMAN; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL EXAMINATION; PRIORITY JOURNAL; SCHOOL CHILD; SEIZURE;

ADRENERGIC ALPHA-AGONISTS; ANTICONVULSANTS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CEREBRAL PALSY; CHILD; CLONIDINE; FEMALE; HUMANS; SEIZURES; STATUS EPILEPTICUS;

EID: 38149059022     PISSN: 08878994     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pediatrneurol.2007.09.016     Document Type: Article

References (18)

1. Connor D.F. Stimulants. Other medications. In: Barkley R.A. (Ed). Attention-deficit hyperactivity disorder: A handbook for diagnosis and treatment. 3rd ed. (2006), Guilford Press, New York 606-47, 660-6
2. Gross-Tsur V., Shalev R.S., Badihi N., and Manor O. Efficacy of methylphenidate in patients with cerebral palsy and attention-deficit hyperactivity disorder (ADHD). J Child Neurol 17 (2002) 863-866
3. Hemmer S.A., Pasternak J.F., Zecker S.G., and Trommer B.L. Stimulant therapy and seizure risk in children with ADHD. Pediatr Neurol 24 (2001) 99-102
4. Connor D.F., Fletcher K.E., and Swanson J.M. A meta-analysis of clonidine for symptoms of attention-deficit hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 38 (1999) 1551-1559
5. Himpel S., Banaschewski T., Heise C.A., and Rothenberger A. The safety of non-stimulant agents for the treatment of attention-deficit hyperactivity disorder. Expert Opin Drug Safety 4 (2005) 311-321
6. Cantwell D.P., Swanson J., and Connor D.F. Case study: Adverse response to clonidine. J Am Acad Child Adolesc Psychiatry 36 (1997) 539-544
7. Klein-Schwartz W. Trends and toxic effects from pediatric clonidine exposures. Arch Pediatr Adolesc Med 156 (2002) 392-396
8. Schmitt H., Druschky K., Hummel C., and Stefan H. Detection of an epileptic mirror focus after oral application of clonidine. Br J Anaesth 83 (1999) 349-351
9. Ahmed S.U., Vallejo R., and Hord E.D. Seizures after a bier block with clonidine and lidocaine. Anesth Analg 99 (2004) 593-594
10. Scaramuzza A., Torresani P., Arisi D., and Rossoni R. Seizures following clonidine test for growth hormone reserve: Unusual presentation of benign partial epilepsy. J Pediatr Endocrinol Metab 13 (2000) 451-452
11. Sitnikova E., and van Luijtelaar G. Reduction of adrenergic neurotransmission with clonidine aggravates spike-waves seizures and alters activity in the cortex and the thalamus in WAG/Rij rats. Brain Res Bull 64 (2005) 533-540
12. Giorgi F.S., Ferrucci M., Lazzeri C., et al. A damage to locus coeruleus neurons converts sporadic seizures into self-sustaining limbic status epilepticus. Eur J Neurosci 17 (2003) 2593-2601
13. Arnsten A.F., Steere J.C., and Hunt R.D. The contribution of alpha-2 noradrenergic mechanisms to prefrontal cortical cognitive function. Arch Gen Psychiatry 53 (1996) 448-455
14. Szot P., Lester M., Laughlin M.L., Palmiter R.D., Liles L.C., and Weinshenker D. The anticonvulsant effects of alpha 2 adrenoreceptor agonists are mediated by distinct populations of alpha 2A-adrenoreceptors. Neuroscience 126 (2004) 795-803
15. 2-adrenoceptors in the modulatory effects of morphine on seizure susceptibility in mice. Epilepsia 43 (2002) 797-804
16. Maura G., Gemignani A., and Raiteri M. Alpha 2-adrenoreceptors in rat hypothalamus and cerebral cortex: Functional evidence for pharmacologically distinct subpopulations. Eur J Pharmacol 116 (1985) 335-339
17. Gobert A., Rivet J.M., Audinot V., Newman-Tancredi A., Cistarelli L., and Millan M.J. Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release. Neuroscience 84 (1998) 413-429
18. Docherty J.R. Age-related changes in adrenergic neuroeffector transmission. Auton Neurosci 96 (2002) 8-12