Reduction of adrenergic neurotransmission with clonidine aggravates spike-wave seizures and alters activity in the cortex and the thalamus in WAG/Rij rats

Brain Research Bulletin

Volumn 64, Issue 6, 2005, Pages 533-540

  Sitnikova, Evgenia ^a   Luijtelaar, Gilles Van ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Absence epilepsy; Clonidine; EEG; Noradrenaline; Spectrum; SWD

Indexed keywords

CLONIDINE;

ABSENCE; ADRENERGIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DRUG EFFECT; ELECTRIC ACTIVITY; ELECTROENCEPHALOGRAM; EPILEPSY; EPILEPTIC DISCHARGE; FRONTAL CORTEX; GENETIC MODEL; GRAND MAL SEIZURE; MALE; NEOCORTEX; NEUROTRANSMISSION; NONHUMAN; NORADRENERGIC SYSTEM; OCCIPITAL CORTEX; PRIORITY JOURNAL; RAT; SEIZURE; SLEEP; SPIKE WAVE; THALAMUS; THALAMUS NUCLEUS; THALAMUS VENTRAL NUCLEUS; WAKEFULNESS;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; BRAIN MAPPING; CEREBRAL CORTEX; CLONIDINE; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; EPILEPSY, ABSENCE; EPINEPHRINE; MALE; RATS; RATS, INBRED STRAINS; RATS, MUTANT STRAINS; SLEEP; SPECTRUM ANALYSIS; THALAMUS; TIME FACTORS; WAKEFULNESS;

EID: 11444265104     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2004.11.004     Document Type: Article

References (50)

1. G. Aston-Jones, S.L. Foote, and F.E. Bloom Anatomy and physiology of locus coeruleus neurons: functional implications M. Ziegler C.R. Lake Norepinephrine. Frontiers of Clinical Neuroscience vol. 2 1984 Williams & Wilkins Baltimore 92 116
2. G. Avanzini, F. Panzica, and M. de Curtis The role of the thalamus in vigilance and epileptogenic mechanism Clin. Neurophysiol. 111 Suppl. 2 2000 19 26
3. S. Berthelsen, and W.A. Pettinger A functional basis for classification of alpha-adrenergic receptors Life Sci. 21 1977 595 606
4. P. Bischoff, D. Mahlstedt, I. Blanc, and J. Schulte am Esch Quantitative topographical electroencephalographic analysis after intravenous clonidine in healthy male volunteers Anesth. Analg. 86 1998 202 207
5. G. Buzsaki, I. Laszlovszky, A. Lajtha, and C. Vadasz Spike-and-wave neocortical patterns in rats: genetic and aminergic control Neuroscience 38 1990 323 333
6. G. Buzsaki, B. Kennedy, B.V. Solt, and M. Ziegler Noradrenergic control of thalamic oscillation: the role of alpha-2 receptors Eur. J. Neurosci. 3 1991 222 229
7. D.B. Bylund, D.C. Eikenberg, J.P. Hieble, S.Z. Langer, R.J. Lefkowitz, K.P. Minneman, P.B. Molinoff, R.R. Ruffolo Jr., and U. Trendelenburg International union of pharmacology nomenclature of adrenoceptors Pharmacol. Rev. 46 1994 121 136
8. M.I. Castro, and J.C. Eisenach Pharmacokinetics and dynamics of intravenous, intrathecal, and epidural clonidine in sheep Anesthesiology 71 1989 418 425
9. L. Cervo, and R. Samanin Clonidine causes antidepressant-like effects in rats by activating alpha 2-adrenoceptors outside the locus coeruleus Eur. J. Pharmacol. 193 1991 309 313
10. B. Civantos Calzada, and A. Aleixandre de Artinano Alpha-adrenoceptor subtypes Pharmacol. Res. 44 2001 195 208
11. A.M. Coenen, and E.L. van Luijtelaar Pharmacological dissociation of EEG and behavior: a basic problem in sleep-wake classification Sleep 14 1991 464 465
12. A.M. Coenen, and E.L. van Luijtelaar Genetic animal models for absence epilepsy: a review of the WAG/Rij strain of rats Behav. Genet. 33 2003 635 655
13. G.M. Drew, A.J. Gower, and A.S. Marriott Alpha 2-adrenoceptors mediate clonidine-induced sedation in the rat Brit. J. Pharmacol. 67 1979 133 141
14. W.H. Drinkenburg, A.M. Coenen, J.M. Vossen, and E.L. van Luijtelaar Spike-wave discharges and sleep-wake states in rats with absence epilepsy Epilepsy Res. 9 1991 218 224
15. G. Emilien Effect of drugs acting on monoaminergic and cholinergic systems on the quantified EEG of rats Neuropsychobiology 21 1989 205 215
16. D.J. Fontana, D.M. Schefke, and R.L. Commissaris Acute versus chronic clonidine treatment effects on conflict behavior in the rat Behav. Pharmacol. 1 1989 201 208
17. A.L. Frankhuyzen, and A.H. Mulder Pharmacological characterization of presynaptic alpha-adrenoceptors modulating [3H]noradrenaline and [3H]5-hydroxytryptamine release from slices of the hippocampus of the rat Eur. J. Pharmacol. 81 1982 97 106
18. N. French Alpha 2-adrenoceptors and I2 sites in the mammalian central nervous system Pharmacol. Therapeut. 68 1995 175 208
19. F.S. Giorgi, C. Pizzanelli, F. Biagioni, L. Murri, and F. Fornai The role of norepinephrine in epilepsy: from the bench to the bedside Neurosci. Biobehav. Rev. 28 2004 507 524
20. J.M. Gobert, V. Rivet, A. Audinot, L. Newman-Tancredi, M.J. Cistarelli, and Millan Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto-and heteroreceptor-mediated control of release Neuroscience 84 1998 413 429
21. H.K. Happe, C.L. Coulter, M.E. Gerety, J.D. Sanders, M. O'Rourke, D.B. Bylund, and L.C. Murrin Alpha-2 adrenergic receptor development in rat CNS: an autoradiographic study Neuroscience 123 2004 167 178
22. L.S. Jones, L.L. Gauger, and J.N. Davis Anatomy of brain alpha 1-adrenergic receptors: in vitro autoradiography with [125I]-heat J. Comp. Neurol. 231 1985 190 208
23. B.E. Jones, and R.Y. Moore Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study Brain Res. 127 1977 25 53
24. V.F. Kitchigina, E.V. Kutyreva, and E.S. Brazhnik Modulation of theta rhythmicity in the medial septal neurons and the hippocampal electroencephalogram in the awake rabbit via actions at noradrenergic alpha2-receptors Neuroscience 120 2003 509 521
25. H. Kleinlogel Spontaneous EEG paroxysms in the rat: effects of psychotropic and alpha-adrenergic agents Neuropsychobiology 13 1985 206 213
26. S.Z. Langer Presynaptic regulation of catecholamine release Biochem. Pharmacol. 23 1974 1793 1800
27. B. Lannes, G. Micheletti, M. Vergnes, C. Marescaux, A. Depaulis, and J.M. Warter Relationship between spike-wave discharges and vigilance levels in rats with spontaneous petit mal-like epilepsy Neurosci. Lett. 94 1988 187 191
28. C. Marescaux, M. Vergnes, and A. Depaulis Neurotransmission in rats' spontaneous generalized nonconvulsive epilepsy Epilepsy Res. Suppl. 8 1992 335 343
29. G. Maura, A. Gemignani, and M. Raiteri Alpha 2-adrenoceptors in rat hypothalamus and cerebral cortex: functional evidence for pharmacologically distinct subpopulations Eur. J. Pharmacol. 116 1985 335 339
30. D.A. McCormick Cholinergic and noradrenergic modulation of thalamocortical processing Trends Neurosci. 12 1989 215 221
31. D.A. McCormick, H.C. Pape, and A. Williamson Actions of norepinephrine in the cerebral cortex and thalamus: implications for function of the central noradrenergic system Prog. Brain Res. 88 1991 293 305
32. G. Micheletti, J.M. Warter, C. Marescaux, A. Depaulis, C. Tranchant, L. Rumbach, and M. Vergnes Effects of drugs affecting noradrenergic neurotransmission in rats with spontaneous petit mal-like seizures Eur. J. Pharmacol. 135 1987 397 402
33. I.S. Midzianovskaia, G.D. Kuznetsova, A.M.L. Coenen, A.M. Spiridonov, and E.L.J.M. van Luijtelaar Electrophysiological, pharmacological characteristics of two types of spike-wave discharges in WAG/Rij rats Brain Res. 911 2001 62 70
34. A. Nuñez, R. Curro Dossi, D. Contreras, and M. Steriade Intracellular evidence for incompatibility between spindle and delta oscillations in thalamocortical neurons of cat Neuroscience 48 1992 75 85
35. T. Osaka, and H. Matsumura Noradrenaline inhibits preoptic sleep-active neurons through alpha 2-receptors in the rat Neurosci. Res. 21 1995 323 330
36. R.H. Pastel, and J.D. Fernstrom The effects of clonidine on EEG wavebands associated with sleep in the rat Brain Res. 300 1984 243 255
37. G. Paxinos, and C. Watson The Rat Brain in Stereotaxic Coordinates 2nd ed. 1986 Academic Press New York
38. W.B. Pickworth, L.G. Sharpe, and V.N. Gupta Morphine-like effects of clonidine on the EEG, slow wave sleep and behavior in the dog Eur. J. Pharmacol. 81 1982 551 557
39. R.R. Ruffolo Jr., and J.P. Hieble Alpha-adrenoceptors Pharmacol Therapeut. 61 1994 1 64
40. J. Scheibner, A.U. Trendelenburg, L. Hein, and K. Starke Alpha 2-adrenoceptors modulating serotonin release: a study in alpha-2 adrenoceptor subtype-deficient mice Brit. J. Pharmacol. 132 2001 925 933
41. W.F. Seidel, M. Maze, W.C. Dement, and D.M. Edgar Alpha-2 adrenergic modulation of sleep: time-of-day-dependent pharmacodynamic profiles of dexmedetomidine and clonidine in the rat J. Pharmacol. Exp. Ther. 275 1995 263 273
42. M. Steriade Neuronal Substrates of Sleep and Epilepsy 2003 Cambridge University Press Cambridge, New York p. 522
43. M. Steriade, and M. Deschenes The thalamus as a neuronal oscillator Brain Res. Rev. 8 1984 1 63
44. T.H. Svensson, B.S. Bunney, and G.K. Aghajanian Inhibition of both noradrenergic and serotonergic neurons in brain by the alpha-adrenergic agonist clonidine Brain Res. 92 1975 291 306
45. L.W. Swanson, and B.K. Hartman The central adrenergic system. An immunofluorescence study of the location of cell bodies and their efferent connections in the rat utilizing dopamine-beta-hydroxylase as a marker J. Comp. Neurol. 163 1975 467 505
46. E.L.J.M. van Luijtelaar Spike-wave discharges and sleep spindles in rats Acta Neurobiol. Exp. (Warsz) 57 1997 113 121
47. E.L.J.M. van Luijtelaar, and A.M.L. Coenen Two types of electrocortical paroxysms in an inbred strain of rats Neurosci. Lett. 70 1986 393 397
48. E.L.J.M. van Luijtelaar, and A.M.L. Coenen Circadian rhythmicity in absence epilepsy in rats Epilepsy Res. 2 1988 331 336
49. G. Vantini, B.D. Perry, R.B. Guchhait, D.C. U'Prichard, and J.M. Stolk Brain epinephrine systems: detailed comparison of adrenergic and noradrenergic metabolism, receptor number and in vitro regulation, in two inbred rat strains Brain Res. 296 1984 49 65
50. D. Weinshenker, and P. Szot The role of catecholamines in seizure susceptibility: New results using genetically-engineered mice Pharmacol. Therapeut. 94 2002 213 233