A meta-analysis of clonidine for symptoms of attention-deficit hyperactivity disorder

Journal of the American Academy of Child and Adolescent Psychiatry

Volumn 38, Issue 12, 1999, Pages 1551-1559

  Connor, Daniel F ^a   Fletcher, Kenneth E ^a   Swanson, James M ^b  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Attention deficit hyperactivity disorder; Clonidine; Meta analysis

Indexed keywords

CLONIDINE;

ARTICLE; ATTENTION DEFICIT DISORDER; CLINICAL TRIAL; COMORBIDITY; DRUG EFFICACY; DRUG SAFETY; HUMAN; HYPOTENSION; IRRITABILITY; META ANALYSIS; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; SEDATION; SKIN IRRITATION; SLEEP DISORDER; XEROSTOMIA;

EID: 0032695861     PISSN: 08908567     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004583-199912000-00017     Document Type: Article

References (28)

1. Blumenthal S, Epps RP, Heavenrich R et al. (1977), Report of the Task Force on Blood Pressure Control in Children. Pediatrics 59(suppl):797-820
2. Cantwell DP, Swanson J, Connor DF (1997), Clonidine use in children: clinical consideration of adverse responses. J Am Acad Child Adolesc Psychiatry 36:539-544
3. Chandran KS (1994), EKG and clonidine (letter). J Am Acad Child Adolesc Psychiatry 33:1351-1352
4. Cohen J (1988), Statistical Power Analysis for the Behavioral Sciences, 2nd ed. Hillsdale, NJ: Erlbaum
5. Connor DF, Barkley RA, Davis HT (in press), A pilot study of methylphenidate, clonidine, or the combination in ADHD comorbid with aggressive oppositional defiant or conduct disorder. Clin Pediatr (Phila)
6. Fankhauser M, Karumanchi V, German M, Yates A, Karumanchi S (1992), A double-blind placebo-controlled study of the efficacy of transdermal clonidine in autism. J Clin Psychiatry 53:77-82
7. Geller B, Reising D, Leonard HL, Riddle MA, Walsh TB (1999), Critical review of tricyclic antidepressant use in children and adolescents. J Am Acad Child Adolesc Psychiatry 38:513-516
8. Gunning B (1992a), Trial group 2: a controlled trial of clonidine in hyperkinetic children. Dissertation, Department of Child/Adolescent Psychiatry, Academic Hospital, Rotterdam, the Netherlands
9. Gunning B (1992b), Trial group 3: a controlled trial of clonidine in hyperkinetic children. Dissertation, Department of Child/Adolescent Psychiatry, Academic Hospital, Rotterdam, the Netherlands
10. Harmon RJ, Riggs PD (1996), Clonidine for posttraumatic stress disorder in preschool children. J Am Acad Child Adolesc Psychiatry 35:1247-1249
11. Hedges LV, Olkin I (1985), Statistical Methods for Meta-Analysis. New York: Academic Press, pp 265-283
12. Hunt RD (1987), Treatment effects of oral and transdermal clonidine in relation to methylphenidate: an open pilot study in ADD-H. Psychopharmacol Bull 23:111-114
13. Hunt RD, Minderaa RB, Cohen DJ (1985), Clonidine benefits children with attention deficit disorder and hyperactivity: report of a double-blind placebo-crossover therapeutic trial. J Am Acad Child Psychiatry 24: 617-629
14. Jaselskis CA, Cook EH, Fletcher KE, Leventhal BL (1992), Clonidine treatment of hyperactive and impulsive children with autistic disorder. J Clin Psychopharmacol 12:322-327
15. Jensen PS, Bhatara VS, Vitiello B, Hoagwood K, Feil M, Burke LB (1999), Psychoactive medication prescribing practices for US children: gaps between research and clinical practice. J Am Acad Child Adolesc Psychiatry 38:557-565
16. Leckman JF, Hardin MT, Riddle MA, Stevenson J, Ort SI, Cohen DJ (1991), Clonidine treatment of Gilles de la Tourette's syndrome. Arch Gen Psychiatry 48:324-328
17. Prince JB, Wilens TE, Biederman J, Spencer TJ, Wozniak JR (1996), Clonidine for sleep disturbances associated with attention-deficit hyperactivity disorder: a systematic chart review of 62 cases. J Am Acad Child Adolesc Psychiatry 35:599-605
18. Rosenthal R (1991), Meta-Analytic Procedures for Social Research. Kewbury Park, CA: Sage
19. Rosenthal R (1994), Parametric measures of effect size. In: The Handbook of Research Synthesis, Cooper H, Hedges LV, eds. New York: Russell Sage Foundation, pp 231-244
20. Rosenthal R (1995), Writing meta-analytic reviews. Psychol Bull 118:183-192
21. Schvehla TJ, Mandoki MW, Sumner GS (1994), Clonidine therapy for comorbid attention deficit hyperactivity disorder and conduct disorder: preliminary findings in a children's inpatient unit. South Med J 87:692-695
22. Singer HS, Brown J, Quaskey S, Rosenberg LA, Mellits ED, Denckla MB (1995), The treatment of attention-deficit hyperactivity disorder in Tourette's syndrome: a double-blind placebo-controlled study with clonidine and desipramine. Pediatrics 95:74-80
23. Steingard R, Biederman J, Spencer T, Wilens T, Gonzales A (1993), Comparison of clonidine response in the treatment of attention-deficit hyperactivity disorder with and without comorbid tic disorders. J Am Acad Child Adolesc Psychiatry 32:350-353
24. Steingard R, Goldberg M, Lee D, DeMaso DR (1994), Adjunctive clonazepam treatment of tic symptoms in children with comorbid tic disorders and ADHD. J Am Acad Child Adolesc Psychiatry 33:394-399
25. Swanson JM, Connor DF, Cantwell D (1999), Debate: combining methylphenidate and clonidine: ill-advised. J Am Acad Child Adolesc Psychiatry 38:617-619
26. Swanson JM, McBurnett K, Christian DL, Wigal T (1995), Stimulant medications and the treatment of children with ADHD. Adv Clin Child Psychol 17:265-232
27. Wilber JA (1980), Clonidine: an introduction. J Cardiovasc Pharmacol 2:S1-S3
28. Wilens TE, Spencer TJ (1999), Debate: combining methylphenidate and clonidine: a clinically sound medication option. J Am Acad Child Adolesc Psychiatry 38:614-616