Synthesis and evaluation of F-18 labeled 2′-deoxy-2′-fluoro-5- methyl-1-β-L-arabinofuranosyluracil (L-[18F]FMAU)

Bulletin of the Korean Chemical Society

Volumn 28, Issue 12, 2007, Pages 2449-2453

  Nam, Hyun Jo ^a   Byung, Seok Moon ^a,c   Su, Hee Hong ^b   Gwang, Il An ^b   Tae, Hyun Choi ^b   Gi, Jeong Cheon ^b   Cho, Jung Hyuck ^a   Kyung, Ho Yoo ^a   Kyo, Chul Lee ^b   Oh, Chang Hyun ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea Institute of Radiation and Medical Science   (South Korea)

^c Inha University   (South Korea)

Author keywords

D 18F FMAU; Fluorine 18; L 18F FMAU; Nucleoside; PET

Indexed keywords

CELLS; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RADIOACTIVE MATERIALS; SUGAR (SUCROSE); SYNTHESIS (CHEMICAL);

ANOMERIC RATIO; GENE IMAGING; RADIOACTIVE SAMPLES; RADIOCHEMICAL PURITY;

NUCLEOTIDES;

EID: 38049153763     PISSN: 02532964     EISSN: 12295949     Source Type: Journal    
DOI: 10.5012/bkcs.2007.28.12.2449     Document Type: Article

References (15)

1. Horn, D. M.; Neeb, L. A.; Colacino, J. M.; Richardson, F. C. Antiviral Res. 1997, 34, 71-74.
2. Colacino, J. M. Antiviral Res. 1996, 29, 125-139.
3. Alauddin, M. M.; Conti, P. S.; Fissekis, J. D. J. Label. Compd. Radiopharm. 2002, 45, 583-590.
4. Alauddin, M. M.; Ghosh, P.; Gelovani, J. G. J. Label. Compd. Radiopharm. 2006, 49, 1079-1088.
5. Samuelsson, L.; Långström, B. J. Label. Compd. Radiopharm. 2003, 46, 263-272.
6. Conti, P. S.; Alauddin, M. M.; Fissekis, J. D.; Watanabe, K. A. Nucl. Med. Biol. 1995, 22, 783-789.
7. Sun, H.; Sloan, A.; Mangner, T. J.; Vaishampayan, U.; Muzik, O.; Collins, J. M.; Douglas, K.; Shields, A. F. Eur. J. Nucl. Med. Mol. Imaging 2005, 32, 15-22.
8. Choi, S. R.; Zhuang, Z. P.; Chacko, A. M.; Acton, P. D.; Tjuvajev-Gelovani, J.; Doubrovin, M.; Chu, D. C. K.; Kung, H. F. Acad. Radiol. 2005, 12, 798-805.
9. Gumina, G.; Chong, Y.; Choo, H.; Song, G. Y.; Chu, C. K. Curr. Top. Med. Chem. 2002, 2, 1065-1086.
10. Reichman, U.; Watanabe, K. A.; Fox, J. J. Carbohydrate Res. 1975, 42, 233-240.
11. Pankiewicz, K. W.; Nawrot, B.; Gadler, H.; Price, R. W.; Watanabe, K. A. J. Med. Chem. 1987, 30, 2314-2316.
12. Tann, C. H.; Brodfuehrer, P. R.; Brundidge, S. P.; Sapino, C.; Howell, H. G. J. Org. Chem. 1985, 50, 3644-3647.
13. Pillarsetty, N.; Shangde, C.; Ageyeva, L.; Finn, R. D.; Blasberg, R. G. J. Med. Chem. 2006, 49, 5377-5381.
14. Du, J.; Choi, Y.; Lee, K.; Chun, B. K.; Hong, J. H.; Chu, C. K. Nucleosides Nucleotides 1999, 18, 187-195.
15. Chou, T. S.; Becke, L. M.; O'Toole, J. C.; Carr, M. A.; Parker, B. E. Tetrahedron Lett. 1996, 37, 17-20.