Synthesis of [18F]-labeled N-3(substituted) thymidine analogues: N-3([18F]fluorobutyl) thymidine ([18F]-FBT) and N-3([18F]fluoropentyl) thymidine ([18F]-FPT) for PET

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 49, Issue 12, 2006, Pages 1079-1088

  Alauddin, Mian M ^a,b   Ghosh, Pradip ^a   Gelovani, Juri G ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b Box 059   (United States)

Author keywords

Fluorine 18; PET; Thymidine; TK1

Indexed keywords

FLUORINE;

ACID HYDROLYSIS; CRUDE PRODUCTS; FLUORINE-18; MESYLATES; RADIOCHEMICAL PURITY; RADIOCHEMICAL YIELD; SPECIFIC ACTIVITY; SYNTHESIS TIME; THYMIDINE; TK1;

HYDROLYSIS;

1 4 TOLUENESULFONYL 4 BENZOYL N BUTANE; 1 4 TOLUENESULFONYL 5 BENZOYL N PENTANE; 1,4 BUTANEDIOL; 3',5' O BIS TETRAHYDROPYRANYL N 3(4 BENZOYL N BUTYL)THYMIDINE; 3',5' O BIS TETRAHYDROPYRANYL N 3(4 FLUORO N BUTYL)THYMIDINE; 3',5' O BIS TETRAHYDROPYRANYL N 3(4 HYDROXY N BUTYL)THYMIDINE; 3',5' O BIS TETRAHYDROPYRANYL N 3(4 METHANE SULFONYL N BUTYL)THYMIDINE; 3',5' O BIS TETRAHYDROPYRANYL N 3(5 BENZOYL N PENTYL)THYMIDINE; 3',5' O BIS TETRAHYDROPYRANYL N 3(5 HYDROXY N PENTYL)THYMIDINE; 3',5' O BIS TETRAHYDROPYRANYL N 3(5METHANESULFONYL N PENTYL)THYMIDINE; 3',5' O TETRAHYDROPYRANYL N 3(5 FLUORO N PENTYL)THYMIDINE; BUTANE; FLUORINE 18; N 3 FLUOROBUTYLTHYMIDINE F 18; N 3 FLUOROPENTYLTHYMIDINE F 18; N 3(4 FLUORO B BUTYL)THYMIDINE; N 3(5 FLUORO N PENTYL)THYMIDINE; PENTANE; THYMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 33846455125     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1127     Document Type: Article

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