Mechanical response of a calcified plaque model to fluid shear force

Annals of Biomedical Engineering

Volumn 34, Issue 10, 2006, Pages 1535-1541

  Lin, Tiantian C ^a   Tintut, Yin ^b   Lyman, Althea ^a   MacK, Wendy ^c   Demer, Linda L ^d   Hsiai, Tzung K ^a  

^a University of Southern California ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Calcifying vascular cells; Nodule; Shear stress, Plaque rupture; Vascular calcification

Indexed keywords

ATHEROSCLEROTIC PLAQUE; CONTROL CULTURES; FLUID SHEAR; FLUID SHEAR STRESS; IN-VITRO; LINEAR PORTIONS; MECHANICAL RESPONSE; MECHANICAL SHEAR; NODULE; PARALLEL-PLATE FLOW; PLAQUE RUPTURE; REPEATED MEASURES; SMOOTH MUSCLE CELLS; VASCULAR CALCIFICATION; VASCULAR CELLS; VEHICLE CONTROL;

BIOMINERALIZATION; CONTROL SYSTEM SYNTHESIS; MINERALOGY; PHOSPHOLIPIDS; SHEAR STRESS;

SHEAR FLOW;

ARTICLE; ATHEROSCLEROSIS; BIOLOGICAL MODEL; BIOMECHANICS; BIOMEDICAL ENGINEERING; BLOOD RHEOLOGY; CALCINOSIS; CELL CULTURE; HUMAN; IN VITRO STUDY; PATHOLOGY; PATHOPHYSIOLOGY; VASCULAR SMOOTH MUSCLE;

ATHEROSCLEROSIS; BIOMECHANICS; BIOMEDICAL ENGINEERING; CALCINOSIS; CELLS, CULTURED; HEMORHEOLOGY; HUMANS; MODELS, CARDIOVASCULAR; MUSCLE, SMOOTH, VASCULAR;

EID: 38049127755     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-006-9182-9     Document Type: Article

References (25)

1. Abedin, M., Y. Tintut, and L. L. Demer. Vascular calcification: Mechanisms and clinical ramifications. Arterioscler. Thromb. Vasc. Biol. 24:1161-1170, 2004.
2. Alpert, J. S. The pathophysiology of acute myocardial infarction. Cardiology 76:85-95, 1989.
3. Detrano, R., T. Hsiai, S. Wang, G. Puentes, J. Fallavollita, P. Shields, W. Stanford, C. Wolfkiel, D. Georgiou, M. Budoff, and J. Reed. Prognostic value of coronary calcification and angiographic stenoses in patients undergoing coronary angiography. J. Am. Coll. Cardiol. 27:285-290, 1996.
4. Ehara, S., Y. Kobayashi, M. Yoshiyama, K. Shimada, Y. Shimada, D. Fukuda, Y. Nakamura, H. Yamashita, H. Yamagishi, K. Takeuchi, T. Naruko, K. Haze, A. E. Becker, J. Yoshikawa, and M. Ueda. Spotty circulation typifies the culprit plaque in patients with acute myocardial infarction: an intravascular ultrasound study. Circulation 110:3424-3429, 2004.
5. Falk, E., P. Shah, and V. Fuster. Coronary plaque disruption. Circulation 92:657-671, 1995.
6. Farrington-Rock, C., N. J. Crofts, M. J. Doherty, B. A. Ashton, C. Griffin-Jones, and A. E. Canfield. Chondrogenic and adipogenic potential of microvascular pericytes. Circulation 110:2226-2232, 2004.
7. Fiorino, A. S. Electron-beam computed tomography, coronary artery calcium, and evaluation of patients with coronary artery disease. Ann. Intern. Med. 128:839-847, 1998.
8. Fujii K., G. Carlier, G. S. Mintz, W. Wijns, A. Colombo, D. Bose, R. Erbel, J. de Ribamar Costa Jr., M. Kimura, K. Sano, R. A. Costa, J. Lui, G. W. Stone, J. W. Moses, M. B. Leon. Intravascular ultrasound study of patterns of calcium in ruptured coronary plaques. Am. J. Cardiol. 96:352-357, 2005. 1540 LIN et al.
9. Garfinke, A., Y. Tintut, D. Petrasek, K. Bostrom, and L. L. Demer. Pattern formation by vascular mesenchymal cells. Proc. Natl. Acad. Sci. 101:9247-9250, 2004.
10. Gimbrone, M. A. and R. S. Cotran. Human vascular smooth muscle in culture: Growth and ultrastructure. Lab. Invest. 33:16-27, 1975.
11. Hillsley, M. V. and J. A. Frangos. Alkaline phosphatase in osteoblasts is down-regulated by pulsatile fluid flow. Calcif. Tissue Int. 60:48-53, 1997.
12. Hsiai, T. K., S. K. Cho, H. M. Honda, S. Hama, M. Navab, L. L. Demer, and C. Ho. Endothelial cell dynamics under pulsating flows: Significance of high versus low shear stress slew rates. Ann. Biomed. Eng. 30:646-656, 2002.
13. Huang, H., R. Virmani, H. Younis, A. P. Burke, R. D. Kamm, and R. T. Lee. The impact of calcification on the biomechanical stability of atherosclerotic plaques. Circulation 103:1051-1056, 2001.
14. Jono, S., Y. Nishizawa, A. Shioi, and H. Morii. Parathyroid hormone-related peptide as a local regulator of vascular calcification: Its inhibitory action on in vitro calcification by bovine vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 17:1135-1142, 1997.
15. Norvell, S. M., M. Alvarez, J. P. Bidwell, and F. M. Pavalko. Fluid shear stress induces beta-catenin signaling in osteoblasts. Calcif. Tissue Int. 75:396-404, 2004.
16. Proudfoot, D., J. N. Skepper, C. M. Shanahan, and P. L. Weissberg. Calcification of human vascular cells in vitro is correlated with high levels of matrix Gla protein and low levels of osteopontin expression. Arterioscler. Thromb. Vasc. Biol. 18:379-388, 1998.
17. Rioufol, G., G. Finet, I. Ginon, X. André-Fouët, R. Rossi, E. Vialle, E. Desjoyaux, G. Convert, J. F. Huret, and T. Tabib. Multiple atherosclerotic plaque rupture in acute coronary syndrome: A three-vessel intravascular ultrasound study. Circulation 106:804-808, 2002.
18. Shao, J., S. Cheng, J. M. Pingsterhaus, N. Charlton-Kachigian, A. P. Lowy, and D. A. Towler. Msx2 promotes cardiovascular calcification by activating paracrine Wnt signals. J. Clin. Invest. 115:1210-1220, 2005.
19. Shioi, A., Y. Nishizawa, S. Jono, H. Koyama, M. Hosoi, and H. Morii. b-Glycerophosphate accelerates calcification in cultured bovine vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 15:2003-2009, 1995.
20. Slager, C. J., J. J. Wentzel, F. J. H. Gijisen, J. C. H. Schuurbiers, A. C. van der Wal, A. F. W. van der Steen, and P. W. Serruys. The role of shear stress in the generation of rupture-prone vulnerable plaques. Nat. Clin. Prac. Cardiovasc. Med. 2:401-405, 2005.
21. Sorescu, G. P., M. Sykes, D. Weiss, M. O. Platt, A. Saha, J. Hwang, N. Boyd, Y. C. Boo, J. D. Vega, W. R. Taylor, and H. Jo. Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response. J. Biol. Chem. 278:31128-33135, 2003.
22. Speer, M. Y. and C. M. Giachelli. Regulation of cardiovascular calcification. Cardiovasc. Pathol. 13:63-70, 2004.
23. Tang, D., C. Yang, S. Kobayashi, J. Zheng, and R. P. Vito. Effect of stenosis on blood flow and artery compression: A three-dimensional fluid-structure interaction model. Ann. Biomed. Eng. 31:1182-1193, 2003.
24. Tintut, Y., Z. Alfonso, T. Saini, K. Radcliff, K. Watson, K. Bostrom, and L. L. Demer. Mutilineage potential of cells from the artery wall. Circulation 108:2505-2510, 2003.
25. Vattikuti, R. and D. A. Towler. Osteogenic regulation of vascular calcification: An early perspective. Am. J. Physiol. Endocrinol. Metab. 286:E686-E696, 2004.