The role of shear stress in the generation of rupture-prone vulnerable plaques

Nature Clinical Practice Cardiovascular Medicine

Volumn 2, Issue 8, 2005, Pages 401-407

  Slager, C J ^a   Wentzel, J J ^a   Gijsen, F J H ^a   Schuurbiers, J C H ^a   van der Wal, A C ^c   van der Steen, A F W ^b   Serruys, P W ^b  

^a Hemodynamics Laboratory   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Arteries; Atherosclerosis; Flow remodeling; Shear stress; Vulnerable plaque

Indexed keywords

ARTERY BLOOD FLOW; ARTERY OCCLUSION; ARTERY THROMBOSIS; ARTERY WALL; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; DISEASE PREDISPOSITION; ENDOTHELIUM CELL; FEEDBACK SYSTEM; HEALING; HUMAN; MECHANICAL STRESS; NONHUMAN; PRIORITY JOURNAL; PROTECTION; REVIEW; RISK FACTOR; SHEAR STRESS; TENSILE STRENGTH; VASCULAR ENDOTHELIUM;

ARTERIOSCLEROSIS; BLOOD FLOW VELOCITY; ENDOTHELIUM, VASCULAR; HUMANS; RUPTURE; STRESS; VASCULAR PATENCY;

EID: 23244438869     PISSN: 17434297     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncpcardio0274     Document Type: Review

References (58)

1. Virmani R et al. (2000) Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 20: 1262-1275
2. Hansson GK et al. (1989) Detection of activated T lymphocytes in the human atherosclerotic plaque. Am J Pathol 135: 169-175
3. Stary HC et al. (1995) A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 92: 1355-1374
4. Falk E et al. (1995) Coronary plaque disruption. Circulation 92: 657-671
5. van der Wal AC et al. (1994) Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. Circulation 89: 36-44
6. Stary HC et al. (1994) A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 89: 2462-2478
7. Canto JG and Iskandrian AE (2003) Major risk factors for cardiovascular disease: debunking the "only 50%" myth. JAMA 290: 947-979
8. VanderLaan PA et al. (2004) Site specificity of atherosclerosis: site-selective responses to atherosclerotic modulators. Arterioscler Thromb Vasc Biol 24: 12-22
9. Walburn FJ and Schneck DJ (1976) A constitutive equation for whole human blood. Biorheology 13: 201-210
10. Kamiya A and Togawa T (1980) Adaptive regulation of wall shear stress to flow change in the canine carotid artery. Am J Physiol 239: H14-H21
11. Doriot PA et al. (2000) In vivo measurements of wall shear stress in human coronary arteries. Coron Artery Dis 11: 495-502
12. Malek AM et al. (1999) Hemodynamic shear stress and its role in atherosclerosis. JAMA 282: 2035-2042
13. Fisher AB et al. (2001) Endothelial cellular response to altered shear stress. Am J Physiol Lung Cell Mol Physiol 281: L529-L533
14. Langille BL et al. (1989) Adaptations of carotid arteries of young and mature rabbits to reduced carotid blood flow. Am J Physiol 256 (Pt 2): H931-H939
15. Malek AM and Izumo S (1995) Control of endothelial cell gene expression by flow. J Biomech 28: 1515-1528
16. Hove JR et al. (2003) Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis. Nature 421: 172-127
17. Velican C and Velican D (1976) Coronary arteries in children up to the age of ten years II. Intimal thickening and its role in atherosclerotic involvement. Med Interne 14: 17-24
18. Stary HC et al. (1992) A definition of the intima of human arteries and of its atherosclerosis-prone regions. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 85: 391-405
19. Millonig G et al. (2001) Network of vascular-associated dendritic cells in intima of healthy young individuals. Arterioscler Thromb Vasc Biol 21: 503-508
20. Stary HC (2000) Lipid and macrophage accumulations in arteries of children and the development of atherosclerosis. Am J Clin Nutr 72 (Suppl): 1297S-1306S
21. Kinlay S et al. (2001) Endothelial function and coronary artery disease. Curr Opin Lipidol 12: 383-289
22. Munzel T and Keaney JF Jr (2001) Are ACE inhibitors a "magic bullet" against oxidative stress? Circulation 104: 1571-1574
23. Rieder MJ et al. (1977) Suppression of angiotensin-converting enzyme expression and activity by shear stress. Circ Res 80: 312-319
24. Hecker M et al. (1992) Role of endothelium-derived bradykinin in the control of vascular tone. J Cardiovasc Pharmacol 20 (Suppl 9): S55-S61
25. Chen XL et al. (2003) Laminar flow induction of antioxidant response element-mediated genes in endothelial cells. A novel anti-inflammatory mechanism. J Biol Chem 278: 703-711
26. Libby P et al. (2002) Inflammation and atherosclerosis. Circulation 105: 1135-1143
27. Tedgui A and Mallat Z (2001) Anti-inflammatory mechanisms in the vascular wall. Circ Res 88: 877-887
28. Dimmeler S et al. (1996) Shear stress inhibits apoptosis of human endothelial cells. FEBS Lett 399: 71-74
29. Inoue N et al. (1996) Shear stress modulates expression of Cu/Zn superoxide dismutase in human aortic endothelial cells. Circ Res 79: 32-37
30. Glagov S et al. (1987) Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med 316: 1371-1375
31. Zarins CK et al. (1987) Shear stress regulation of artery lumen diameter in experimental atherogenesis. J Vasc Surg 5: 413-420
32. Kubis N et al. (2001) Adaptive common carotid arteries remodeling after unilateral internal carotid artery occlusion in adult patients. Cardiovasc Res 50: 597-602
33. Bentzon JF et al. (2003) Expansive remodeling is a response of the plaque-related vessel wall in aortic roots of ApoE-deficient mice: an experiment of nature. Arterioscler Thromb Vasc Biol 23: 257-262
34. Varnava AM and Davies MJ (2001) Relation between coronary artery remodelling (compensatory dilatation) and stenosis in human native coronary arteries. Heart 86: 207-211
35. Clarijs JA et al. (1997) Compensatory enlargement in coronary and femoral arteries is related to neither the extent of plaque-free vessel wall nor lesion eccentricity. A postmortem study. Arterioscler Thromb Vasc Biol 17: 2617-2621
36. von Birgelen C et al. (1998) Atherosclerotic coronary lesions with inadequate compensatory enlargement have smaller plaque and vessel volumes: observations with three-dimensional intravascular ultrasound in vivo. Heart 79: 137-142
37. Ito K et al. (2002) Effect of disease eccentricity on compensatory remodeling of coronary arteries: evidence from intravascular ultrasound before interventions. Int J Cardiol 86: 99-105
38. Pasterkamp G et al. (1998) Relation of arterial geometry to luminal narrowing and histologic markers for plaque vulnerability: the remodeling paradox. J Am Coll Cardiol 32: 655-662
39. Smits PC et al. (1999) Angioscopic complex lesions are predominantly compensatory enlarged: an angioscopy and intracoronary ultrasound study. Cardiovasc Res 41: 458-464
40. Girerd X et al. (1996) Remodeling of the radial artery in response to a chronic increase in shear stress. Hypertension 27: 799-803
41. Burrig KF (1991) The endothelium of advanced arteriosclerotic plaques in humans. Arterioscler Thromb 11: 1678-1689
42. Tricot O et al. (2000) Relation between endothelial cell apoptosis and blood flow direction in human atherosclerotic plaques. Circulation 101: 2450-2453
43. Green DJ et al. (2004) Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol 561: 1-25
44. Mann GV et al. (1965) Physical fitness and immunity to heart disease in Masai. Lancet 2: 1308-1310
45. Mann GV et al. (1972) Atherosclerosis in the Masai. Am J Epidemiol 95: 26-37
46. Schoenhagen P et al. (2000) Extent and direction of arterial remodeling in stable versus unstable coronary syndromes: an intravascular ultrasound study. Circulation 101: 598-603
47. Richardson PD et al. (1989) Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques. Lancet 2: 941-944
48. Davies MJ and Thomas A (1984) Thrombosis and acute coronary-artery lesions in sudden cardiac ischemic death. N Engl J Med 310: 1137-1140
49. Burke AP et al. (2001) Healed plaque ruptures and sudden coronary death: evidence that subclinical rupture has a role in plaque progression. Circulation 103: 934-940
50. Ambrose JA et al. (1988) Angiographic progression of coronary artery disease and the development of myocardial infarction. J Am Coll Cardiol 12: 56-62
51. Yokoya K et al. (1999) Process of progression of coronary artery lesions from mild or moderate stenosis to moderate or severe stenosis: A study based on four serial coronary arteriograms per year. Circulation 100: 903-909
52. Cheng GC et al. (1993) Distribution of circumferential stress in ruptured and stable atherosclerotic lesions. A structural analysis with histopathological correlation. Circulation 87: 1179-1187
53. Beach KW et al. (1993) Carotid artery intraplaque hemorrhage and stenotic velocity. Stroke 24: 314-319
54. Burke AP et al. (2002) Morphological predictors of arterial remodeling in coronary atherosclerosis. Circulation 105: 297-303
55. Wentzel JJ et al. (2003) Extension of increased atherosclerotic wall thickness into high shear stress regions is associated with loss of compensatory remodeling. Circulation 108: 17-23
56. Slager CJ et al. (2000) True 3-dimensional reconstruction of coronary arteries in patients by fusion of angiography and IVUS (ANGUS) and its quantitative validation. Circulation 102: 511-516
57. Krams R et al. (1997) Evaluation of endothelial shear stress and 3D geometry as factors determining the development of atherosclerosis and remodeling in human coronary arteries in vivo. Combining 3D reconstruction from angiography and IVUS (ANGUS) with computational fluid dynamics. Arterioscler Thromb Vasc Biol 17: 2061-2065
58. Stone PH et al. (2003) Effect of endothelial shear stress on the progression of coronary artery disease, vascular remodeling, and in-stent restenosis in humans: in vivo 6-month follow-up study. Circulation 108: 438-444