Insulin-inhibited and stimulated cultured vascular smooth muscle cell migration are related to divergent effects on protein phosphatase-2A and autonomous calcium/calmodulin-dependent protein kinase II

Atherosclerosis

Volumn 196, Issue 1, 2008, Pages 227-233

  Yang, Ming ^a   Kahn, Andrew M ^a  

^a Department of Internal Medicine   (United States)

Author keywords

Angiotension II; Calcium calmodulin dependent protein kinase II; Cyclic GMP; Insulin; Nitric oxide; Protein phosphatase 2A; Vascular smooth muscle cell migration

Indexed keywords

APOCYNIN; CYCLIC GMP; INSULIN; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE (CALCIUM,CALMODULIN) II;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

5'-GUANYLIC ACID; ANGIOTENSIN II; ANIMALS; AORTA, THORACIC; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL MOVEMENT; CELLS, CULTURED; INSULIN; MALE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NITRIC OXIDE; PROTEIN PHOSPHATASE 2; RATS; RATS, SPRAGUE-DAWLEY;

EID: 38049081547     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2007.04.050     Document Type: Article

References (34)

1. Stout R.W. Insulin and atheroma-20-year perspective. Diabetes Care 13 (1990) 631-654
2. Asakura Y., Suzuki M., Nonogi H., et al. Restenosis after percutaneous transluminal coronary angioplasty in patients with non-insulin-dependent diabetes mellitus (NIDDM). J Cardiovasc Risk 5 5-6 (1998) 331-334
3. Osani H., Kanayama H., Miyazaki Y., et al. Usefulness of enhanced insulin secretion during an oral glucose tolerance test as a predictor of restenosis after direct percutaneous transluminal coronary angioplasty during acute myocardial infarction in patients without diabetes mellitus. Am J Cardiol 81 (1998) 698-701
4. Casscells W. Migration of smooth muscle and endothelia cells; critical events in restenosis. Circulation 86 (1992) 723-729
5. Kahn A.M., Allen J.C., Seidel C.L., and Zhang S. Insulin inhibits migration of vascular smooth muscle cells with nitric oxide synthase. Hypertension 35 Part 2 (2000) 303-306
6. Zhang S., Yang Y., Kone B.C., Allen J.C., and Kahn A.M. Insulin-stimulated cyclic GMP inhibits vascular smooth muscle cell migration by inhibiting Ca/calmodulin-dependent protein kinase II. Circulation 107 (2003) 1539-1544
7. Yang M., Foster E., and Kahn A.M. Insulin-stimulated NAD(P)H oxidase activity increases migration of cultured vascular smooth muscle cells. Am J Hypertens 18 (2005) 1329-1334
8. Lundberg M.S., Curto K.A., Bilato C., Monticone R.E., and Crow M.T. Regulation of vascular smooth muscle migration by mitogen-activated protein kinase and calcium/calmodulin-dependent protein kinase II signaling pathways. J Mol Cell Cardiol 30 (1998) 2377-2384
9. Pauly R.R., Bilato C., Sollott S.J., et al. Role of calcium/calmodulin-dependent protein kinase II in the regulation of vascular smooth muscle cell migration. Circulation 15 91 (1995) 1107-1115
10. 2+/calmodulin-dependent protein kinase II in vascular smooth muscle cells. J Biol Chem 2 271 (1996) 2506-2513
11. 2+/calmodulin-dependent protein kinase II. J Biol Chem 278 (2001) 3719-3722
12. Knapp J., Aleth S., Balzer F., Schmitz W., and Neumann J. Calcium-independent activation of the contractile apparatus in smooth muscle of mouse aorta by protein phosphatase inhibition. Naunyn-Schmiedeberg's Arch Pharmacol 366 (2002) 562-569
13. Colbran R.J. Protein phosphatases and calcium/calmodulin-dependent protein kinase II-dependent synaptic plasticity. J Neurosci 24 (2004) 8404-8409
14. 2+/calmodulin-dependent protein kinase II in vascular smooth muscle cells. Am J Path 161 (2002) 1893-1901
15. Rao R.K., and Clayton L.W. Regulation of protein phosphatase 2A by hydrogen peroxide and glutathionylation. Biochem Biophys Res Commun 293 (2002) 610-615
16. Griendling K.K., Minieri C.A., Ollerenshaw J.D., and Alexander R.W. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 74 (1994) 1141-1148
17. Lassegue B., and Clempus R.E. Vascular NAD(P)H oxidases: specific features, expression, and regulation. Am J Physiol 285 (2003) R277-R297
18. Cohen P., Klumpp S., and Schelling D.L. An improved procedure for identifying and quantiating protein phosphatases in mammalian tissues. FEBS Lett 250 (1989) 596-600
19. Knap J., Boknik P., Lüss I., et al. The protein phosphatase inhibitor cantharidin alters vascular endothelial cell permeability. J Pharmacol Exp Ther 289 (1999) 1480-1486
20. Kahn A.M., Allen J.C., Seidel C.L., et al. Insulin increases NO-stimulated guanylate cyclase activity in cultured VSMC while raising redox potential. Am J Physiol Endocrinol Metab 278 (2000) E627-E633
21. + redox state increases NAD(P)H oxidase activity in cultured rat vascular smooth muscle cells. Am J Hypertens 19 (2006) 587-592
22. Hart B.A., and Simons J.M. Metabolic activation of phenols by stimulated neutrophils: a concept for a selective type of anti-inflammatory drug. Biotechnol Ther 3 (1992) 119-135
23. Meyer J.W., and Schmitt M.E. A central role for the endothelial NADPH oxidase in atherosclerosis. FEBS Lett 472 (1992) 1-4
24. Jacob A., Molkentin J.D., Smolenski A., Lohmann S.M., and Begum N. Insulin inhibits PDGF-directed VSMC migration via NO/cGMP increase of MKP-1 and its inactivation of MAPKs. Am J Physiol 283 (2002) C704-C713
25. Low Wang C.C., Gurevich I., and Draznin B. Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways. Diabetes 52 (2003) 2562-2569
26. 2 levels: essential role of cGMP. Am J Physiol 286 (2004) H2103-H2112
27. Knapp J., Bokník P., Huke S., et al. The mechanism of action of cantharidin in smooth muscle. Br J Pharmacol 123 (1998) 911-919
28. Honkanen R.E. Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A. FEBS Lett 330 (1993) 283-286
29. Moreno H., Vega-Saenz de Miera E., Nadal M.S., Amarillo Y., and Rudy B. Modulation of Kv3 potassium channels expressed in CHO cells by a nitric oxide-activated phosphatase. J Physiol 5303 (2001) 345-358
30. + currents by cGMP-dependent protein kinase in tracheal smooth muscle and Chinese hamster ovary cells. J Biol Chem 271 (1996) 19760-19767
31. Howe C.J., LaHair M.M., McCubrey J.A., and Frankin R.A. Redox regulation of the calcium/calmodulin-dependent protein kinases. J Biol Chem 279 (2004) 44573-44581
32. Nguyen A., Peng C., and Cai H. Role of CaMKII in hydrogen perioxide activation of ERK1/2, p38 MAPK, HSP27 and actin reorganization in endothelial cells. FEBS Lett 572 (2004) 307-313
33. Duff J.L., Monia B.P., and Berk B.C. Mitogen-activated protein (MAP) kinase is regulated by the MAP kinase phosphatase (MKP-1) in vascular smooth muscle cells. J Biol Chem 270 (1995) 7161-7166
34. Graf K., Xi X., Yang D., et al. Mitogen-activated protein kinase activation is involved in platelet-derived growth factor-directed migration by vascular smooth muscle cells. Hypertension 29 (1997) 334-339