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Christiansen, C.1
Rodbro, P.2
Lund, M.3
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52
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85136378010
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• Yang YZ, Lewis J, Epstein S, Metz D: Long-term proton pump inhibitor therapy and risk of hip fracture. JAMA 2006, 296:2947-2953. PPIs reduce the production of gastric acid, which is needed to break down calcium supplements and other nutrients. The long-term use of these agents is associated with an increased risk of hip fractures. Although the increased risk was not large, many elderly individuals take both calcium supplements and use these agents chronically. Physicians should try to taper their patients off PPIs if they are no longer clinically indicated or separate the ingestion of calcium supplements and use of PPIs by 12 hours.
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• Yang YZ, Lewis J, Epstein S, Metz D: Long-term proton pump inhibitor therapy and risk of hip fracture. JAMA 2006, 296:2947-2953. PPIs reduce the production of gastric acid, which is needed to break down calcium supplements and other nutrients. The long-term use of these agents is associated with an increased risk of hip fractures. Although the increased risk was not large, many elderly individuals take both calcium supplements and use these agents chronically. Physicians should try to taper their patients off PPIs if they are no longer clinically indicated or separate the ingestion of calcium supplements and use of PPIs by 12 hours.
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