Induction of podoplanin by transforming growth factor-β in human fibrosarcoma

FEBS Letters

Volumn 582, Issue 2, 2008, Pages 341-345

  Suzuki, Hiroyuki ^a   Kato, Yukinari ^b   Kaneko, Mika Kato ^b   Okita, Yukari ^a   Narimatsu, Hisashi ^b   Kato, Mitsuyasu ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Fibrosarcoma; Platelet aggregation; Podoplanin; Smad; TGF

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; PODOPLANIN; SHORT HAIRPIN RNA; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CONTROLLED STUDY; FIBROSARCOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; THROMBOCYTE AGGREGATION; TUMOR CELL;

BASE SEQUENCE; CELL LINE; DNA PRIMERS; FIBROSARCOMA; FLOW CYTOMETRY; HUMANS; MEMBRANE GLYCOPROTEINS; PLATELET AGGREGATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 38049048241     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.12.028     Document Type: Article

References (25)

1. Breiteneder-Geleff S., Matsui K., Soleiman A., Meraner P., Poczewski H., Kalt R., Schaffner G., and Kerjaschki D. Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis. Am. J. Pathol. 151 (1997) 1141-1152
2. Schacht V., Ramirez M.I., Hong Y.K., Hirakawa S., Feng D., Harvey N., Williams M., Dvorak A.M., Dvorak H.F., Oliver G., and Detmar M. T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. EMBO J. 22 (2003) 3546-3556
3. Kato Y., Kaneko M.K., Kuno A., Uchiyama N., Amano K., Chiba Y., Hasegawa Y., Hirabayashi J., Narimatsu H., Mishima K., and Osawa M. Inhibition of tumor cell-induced platelet aggregation using a novel anti-podoplanin antibody reacting with its platelet-aggregation-stimulating domain. Biochem. Biophys. Res. Commun. 349 (2006) 1301-1307
4. Mishima K., Kato Y., Kaneko M.K., Nishikawa R., Hirose T., and Matsutani M. Increased expression of podoplanin in malignant astrocytic tumors as a novel molecular marker of malignant progression. Acta Neuropathol. (Berl.) 111 (2006) 483-488
5. Kato Y., Fujita N., Kunita A., Sato S., Kaneko M., Osawa M., and Tsuruo T. Molecular identification of aggrus/T1alpha as a platelet aggregation-inducing factor expressed in colorectal tumors. J. Biol. Chem. 278 (2003) 51599-51605
6. Kaneko M., Kato Y., Kunita A., Fujita N., Tsuruo T., and Osawa M. Functional sialylated O-glycan to platelet aggregation on aggrus (T1alpha/podoplanin) molecules expressed in Chinese hamster ovary cells. J. Biol. Chem. 279 (2004) 38838-38843
7. Kaneko M.K., Kato Y., Kitano T., and Osawa M. Conservation of a platelet activating domain of aggrus/podoplanin as a platelet aggregation-inducing factor. Gene 378 (2006) 52-57
8. Kaneko M.K., Kato Y., Kameyama A., Ito H., Kuno A., Hirabayashi J., Kubota T., Amano K., Chiba Y., Hasegawa Y., Sasagawa I., Mishima K., and Narimatsu H. Functional glycosylation of human podoplanin: glycan structure of platelet aggregation-inducing factor. FEBS Lett. 581 (2007) 331-336
9. Suzuki-Inoue K., Kato Y., Inoue O., Kaneko M.K., Mishima K., Yatomi Y., Narimatsu H., and Ozaki Y. Involvement of the snake toxin receptor CLEC-2 in podoplanin-mediated platelet activation by cancer cells. J. Biol. Chem. 282 (2007) 25993-26001
10. Kato Y., Kaneko M.K., Kunita A., Ito H., Kameyama A., Ogasawara S., Matsuura N., Hasegawa Y., Suzuki-Inoue K., Inoue O., Ozaki Y., and Narimatsu H. Molecular analysis of the pathophysiological binding of the platelet aggregation-inducing factor podoplanin to the C-type lectin-like receptor CLEC-2. Cancer Sci. 99 (2008) 54-61
11. Heldin C.H., Miyazono K., and ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 390 (1997) 465-471
12. Massague J., Seoane J., and Wotton D. Smad transcription factors. Gene Dev. 19 (2005) 2783-2810
13. Martin-Villar E., Megias D., Castel S., Yurrita M.M., Vilaro S., and Quintanilla M. Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition. J. Cell Sci. 119 (2006) 4541-4553
14. Groger M., Loewe R., Holnthoner W., Embacher R., Pillinger M., Herron G.S., Wolff K., and Petzelbauer P. IL-3 induces expression of lymphatic markers Prox-1 and podoplanin in human endothelial cells. J. Immunol. 173 (2004) 7161-7169
15. Goumans M.J., Valdimarsdottir G., Itoh S., Rosendahl A., Sideras P., and ten Dijke P. Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors. EMBO J. 21 (2002) 1743-1753
16. Chen C.R., Kang Y., and Massague J. Defective repression of c-myc in breast cancer cells: a loss at the core of the transforming growth factor beta growth arrest program. Proc. Natl. Acad. Sci. USA 98 (2001) 992-999
17. Akhurst R.J., and Derynck R. TGF-beta signaling in cancer - a double-edged sword. Trends Cell Biol. 11 (2001) S44-S51
18. Shirakihara T., Saitoh M., and Miyazono K. Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta. Mol. Biol. Cell. 18 (2007) 3533-3544
19. Peinado H., Quintanilla M., and Cano A. Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J. Biol. Chem. 278 (2003) 21113-21123
20. Kondo M., Cubillo E., Tobiume K., Shirakihara T., Fukuda N., Suzuki H., Shimizu K., Takehara K., Cano A., Saitoh M., and Miyazono K. A role for Id in the regulation of TGF-beta-induced epithelial-mesenchymal transdifferentiation. Cell Death Differ. 11 (2004) 1092-1101
21. Kang Y., Siegel P.M., Shu W., Drobnjak M., Kakonen S.M., Cordon-Cardo C., Guise T.A., and Massague J. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell. 3 (2003) 537-549
22. Kwak H.J., Park M.J., Cho H., Park C.M., Moon S.I., Lee H.C., Park I.C., Kim M.S., Rhee C.H., and Hong S.I. Transforming growth factor-beta1 induces tissue inhibitor of metalloproteinase-1 expression via activation of extracellular signal-regulated kinase and Sp1 in human fibrosarcoma cells. Mol. Cancer Res. 4 (2006) 209-220
23. Massague J., Blain S.W., and Lo R.S. TGFbeta signaling in growth control, cancer, and heritable disorders. Cell 103 (2000) 295-309
24. Hantusch B., Kalt R., Krieger S., Puri C., and Kerjaschki D. Sp1/Sp3 and DNA-methylation contribute to basal transcriptional activation of human podoplanin in MG63 versus Saos-2 osteoblastic cells. BMC Mol. Biol. 8 (2007) 20
25. Moustakas A., and Kardassis D. Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members. Proc. Natl. Acad. Sci. USA 95 (1998) 6733-6738