Mesenchymal stem cells transduced by vascular endothelial growth factor gene for ischemic random skin flaps

Plastic and Reconstructive Surgery

Volumn 121, Issue 1, 2008, Pages 59-69

  Zheng, Yan ^a   Yi, Chenggang ^a   Xia, Wei ^a   Ding, Tan ^a   Zhou, Zhiqiang ^a   Han, Yan ^a   Guo, Shuzhong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROMETHYL 1,1' DIOCTADECYL 3,3,3',3' TETRAMETHYLINDOCARBOCYANINEPERCHLORATE; LIPOSOME; PERCHLORATE; PLASMID DNA; UNCLASSIFIED DRUG; VASCULOTROPIN 165;

ANALYTIC METHOD; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD FLOW; BONE MARROW; CAPILLARY DENSITY; CELL CULTURE; CELL ISOLATION; COMPARATIVE STUDY; CONTROLLED STUDY; GENE; GENETIC TRANSDUCTION; GRAFT SURVIVAL; ISCHEMIC RANDOM SKIN FLAP; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN FLAP; VASCULAR ENDOTHELIAL GROWTH FACTOR 165 GENE; VASCULAR ENDOTHELIAL GROWTH FACTOR GENE;

ANIMALS; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; ISCHEMIA; MESENCHYMAL STEM CELL TRANSPLANTATION; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RATS, SPRAGUE-DAWLEY; SKIN TRANSPLANTATION; SURGICAL FLAPS; TISSUE SURVIVAL; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 38049036269     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.prs.0000293877.84531.5a     Document Type: Article

References (34)

1. Lubiatowski, P., Goldman, C. K., Gurunluoglu, R., et al. Enhancement of epigastric skin flap survival by adenovirusmediated VEGF gene therapy. Plast. Reconstr. Surg. 109: 1986, 2002.
2. Kubota, Y., Kishi, K., Satoh, H., et al. Transplanted endothelial progenitor cells augment the survival areas of rat dorsal flaps. Cell Transplant. 12: 647, 2003.
3. Park, S., Tepper, O. M., Galiano, R. D., et al. Selective recruitment of endothelial progenitor cells to ischemic tissues with increased neovascularization. Plast. Reconstr. Surg. 113: 284, 2004.
4. Josko, J., Gwozdz, B., Jedrzejowska-Szypulka, H., et al. Vascular endothelial growth factor (VEGF) and its effect on angiogenesis. Med. Sci. Monit. 6: 1047, 2000.
5. Toole, G., MacKenzie, D., Lindeman, R., et al. Vascular endothelial growth factor gene therapy in ischaemic rat skin flaps. Br. J. Plast. Surg. 55: 55, 2002.
6. Waller, W., Lee, J., Zhang, F., et al. Gene therapy in flap survival. Microsurgery 24: 168, 2004.
7. Vale, P. R., Losordo, D. W., Milliken, C. E., et al. Left ventricular electromechanical mapping to assess efficacy of ph-VEGF(165) gene transfer for therapeutic angiogenesis in chronic myocardial ischemia. Circulation 102: 965, 2000.
8. Rosengart, T. K., Lee, L. Y., Patel, S. R., et al. Angiogenesis gene therapy: Phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease. Circulation 100: 468, 1999.
9. Matsumoto, R., Omura, T., Yoshiyama, M., et al. Vascular endothelial growth factor-expressing mesenchymal stem cell transplantation for the treatment of acute myocardial infarction. Arterioscler. Thromb. Vasc. Biol. 25: 1168, 2005.
10. Chavakis, E., and Dimmeler, S. Regulation of endothelial cell survival and apoptosis during angiogenesis. Arterioscler. Thromb. Vasc. Biol. 22: 887, 2002.
11. Dimmeler, S., and Zeiher, A. M. Endothelial cell apoptosis in angiogenesis and vessel regression. Circ. Res. 87: 434, 2000.
12. Zheng, Y., Yi, C. G., and Guo, S. Z. Progress of research on relationship of angiogenesis and apoptosis. Chin. J. Aesthet. Med. 14: 768, 2005.
13. Jiang, Y., Jahagirdar, B. N., Reinhardt, R. L., et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418: 41, 2002.
14. Pittenger, M. F., and Martin, B. J. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ. Res. 95: 9, 2004.
15. Dai, W., Hale, S. L., Martin, B. J., et al. Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: Short- and long-term effects. Circulation 112: 214, 2005.
16. Silva, G. V., Litovsky, S., Assad, J. A., et al. Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model. Circulation 111: 150, 2005.
17. Amado, L. C., Saliaris, A. P., Schuleri, K. H., et al. Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction. Proc. Natl. Acad. Sci. U.S.A. 102: 11474, 2005.
18. Weissberg, P. L., and Qasim, A. Stem cell therapy for myocardial repair. Heart 91: 696, 2005.
19. Wu, X., Huang, L., Zhou, Q., et al. Mesenchymal stem cells participating in ex vivo endothelium repair and its effect on vascular smooth muscle cells growth. Int. J. Cardiol. 105: 274, 2005.
20. Simman, R., Craft, C., and Mckinney, B. Improved survival of ischemic random skin flaps through the use of bone marrow nonhematopoietic stem cells and angiogenic growth factors. Ann. Plast. Surg. 54: 546, 2005.
21. Yi, C. G., Xia, W., Zheng, Y., et al. Transplantation of endothelial progenitor cells transferred by vascular endothelial growth factor gene for vascular regeneration of ischemic flaps. J. Surg. Res. 135: 100, 2006.
22. Kalka, C., Masuda, H., Takahashi, T., et al. Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc. Natl. Acad. Sci. U.S.A. 97: 3422, 2000.
23. Schmeisser, A., and Strasser, R. H. Phenotypic overlap between hematopoietic cells with suggested angioblastic potential and vascular endothelial cells. J. Hematother. Stem Cell Res. 11: 69, 2002.
24. Urbich, C., and Dimmeler, S. Endothelial progenitor cells: Characterization and role in vascular biology. Circ. Res. 95: 343, 2004.
25. Asahara, T., Murohara, T., and Sullivan, A. Isolation of putative progenitor endothelial cells for angiogenesis. Science 275: 964, 1997.
26. Han, S. K., Chun, K. W., Gye, M. S., and Kim, W. K. The effect of human bone marrow stromal cells and dermal fibroblasts on angiogenesis. Plast. Reconstr. Surg. 117: 829, 2006.
27. Nagaya, N., Kangawa, K., Itoh, T., et al. Transplantation of mesenchymal stem cells improves cardiac function in a rat model of dilated cardiomyopathy. Circulation 112: 1128, 2005.
28. Oswald, J., Boxberger, S., Jorgensen, B., et al. Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells 22: 377, 2004.
29. Li, Q. F., Reis, E. D., Zhang, W. X., et al. Accelerated flap prefabrication with vascular endothelial growth factor. J. Reconstr. Microsurg. 16: 45, 2000.
30. Zang, F., Fischer, K., Komorowska-Timek, E., et al. Improvement of skin paddle survival by application of vascular endothelial growth factor in a rat TRAM flap model. Ann. Plast. Surg. 46: 314, 2001.
31. Zhang, F., Waller, W., and Lineaweaver, W. C. Growth factors and flap survival. Microsurgery 24: 162, 2004.
32. Wang, Y., Haider, H. K., Ahmad, N., et al. Combining pharmacological mobilization with intramyocardial delivery of bone marrow cells over-expressing VEGF is more effective for cardiac repair. J. Mol. Cell. Cardiol. 40: 736, 2006.
33. Losordo, D. W., and Dimmeler, S. Therapeutic angiogenesis and vasculogenesis for ischemic disease: Part I. Angiogenic cytokines. Circulation 109: 2487, 2004.
34. Kawamoto, A., Murayama, T., Kusano, K., et al. Synergistic effect of bone marrow mobilization and vascular endothelial growth factor-2 gene therapy in myocardial ischemia. Circulation 110: 1398, 2004.